Hypertension research

Many patients with high blood pressure try to follow a healthy diet, exercise, and take medications — yet their blood pressure is still high.  

A/Prof Walton is coordinating the SPYRAL Hypertension study, a multi-centre, international, randomised, interventional study, using renal denervation.  The purpose of the Trial is to provide information about the safety and efficacy of the investigational Symplicity Spyral™ catheter and the Symplicity G3™ generator to help reduce blood pressure.   To be eligible for the Trial, patients must be between the ages of 20 and 80 and have uncontrolled hypertension, with readings of 150-180/90mmHg.

Current publications

Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial

View the publication at The Lancet
A/Prof Antony Walton

Dr Tony Walton is Deputy Director and Head of Catheter Laboratory in the Department of Cardiology.  He is a clinician, interventional cardiologist who specialises in structural heart procedures.

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A/Prof Ingrid Hopper

Associate Professor Ingrid Hopper is a consultant physician at Alfred Health.

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Prof Murray Esler
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