Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Impact of rosuvastatin on atherosclerosis in people with HIV at moderate cardiovascular risk

Trevillyan, Janine M.; Dart, Anthony; Paul, Eldho; Cavassini, Matthias; Fehr, Jan; Staehelin, Cornelia; Dewar, Elizabeth M.; Hoy, Jennifer F.; Calmy, Alexandra

(2021), AIDS, 194, 110632

DOI: 10.1097/QAD.0000000000002764

Understanding how Victoria, Australia gained control of its second COVID-19 wave

Trauer, James M.; Lydeamore, Michael J.; Dalton, Gregory W.; Pilcher, David; Meehan, Michael T.; McBryde, Emma S.; Cheng, Allen C.; Sutton, Brett; Ragonnet, Romain

(2021), NAT COMMUN, 35(4), 619-624

DOI: 10.1038/s41467-021-26558-4

Hearing the voices of Australian healthcare workers during the COVID-19 pandemic

Ananda-Rajah, Michelle; Veness, Benjamin; Berkovic, Danielle; Parker, Catriona; Kelly, Greg; Ayton, Darshini

(2021), BMJ Leader, 5(1), 31-35

DOI: 10.1136/leader-2020-000386

Multiply spliced HIV RNA is a predictive measure of virus production ex vivo and in vivo following reversal of HIV latency

Zerbato, Jennifer M.; Khoury, Georges; Zhao, Wei; Gartner, Matthew J.; Pascoe, Rachel D.; Rhodes, Ajantha; Dantanarayana, Ashanti; Gooey, Megan; Anderson, Jenny; Bacchetti, Peter; Deeks, Steven G.; McMahon, James; Roche, Michael; Rasmussen, Thomas A.; Pur

(2021), EBIOMEDICINE, 65, 103241

DOI: 10.1016/j.ebiom.2021.103241

The Membrane Composition Defines the Spatial Organization and Function of a Major Acinetobacter baumannii Drug Efflux System

Zang, Maoge; MacDermott-Opeskin, Hugo; Adams, Felise G.; Naidu, Varsha; Waters, Jack K.; Carey, Ashley B.; Ashenden, Alex; McLean, Kimberley T.; Brazel, Erin B.; Jiang, Jhih-Hang; Panizza, Alessandra; Trappetti, Claudia; Paton, James C.; Peleg, Anton Y.;

(2021), MBIO, 12(3), e0107021

DOI: 10.1128/mBio.01070-21

Risk mapping for COVID-19 outbreaks in Australia using mobility data

Zachreson, Cameron; Mitchell, Lewis; Lydeamore, Michael J.; Rebuli, Nicolas; Tomko, Martin; Geard, Nicholas

(2021), J R SOC INTERFACE, 18(174), 20200657

DOI: 10.1098/rsif.2020.0657

Epigenetic scars of CD8+ T cell exhaustion persist after cure of chronic infection in humans

Yates, Kathleen B.; Tonnerre, Pierre; Martin, Genevieve E.; Gerdemann, Ulrike; Al Abosy, Rose; Comstock, Dawn E.; Weiss, Sarah A.; Wolski, David; Tully, Damien C.; Chung, Raymond T.; Allen, Todd M.; Kim, Arthur Y.; Fidler, Sarah; Fox, Julie; Frater, John;

(2021), NAT IMMUNOL, 22(8), 1020-1029

DOI: 10.1038/s41590-021-00979-1

Recovery of small plasmid sequences via Oxford Nanopore sequencing

Wick, Ryan; Judd, Louise M.; Wyres, Kelly L.; Holt, Kathryn E.

(2021), MICROBIOL GENOMICS, 7(8), 631

DOI: 10.1099/mgen.0.000631

Trycycler: consensus long-read assemblies for bacterial genomes

Wick, Ryan R.; Judd, Louise M.; Cerdeira, Louise T.; Hawkey, Jane; Méric, Guillaume; Vezina, Ben; Wyres, Kelly L.; Holt, Kathryn E.

(2021), GENOME BIOL, 22(1), 266

DOI: 10.1186/s13059-021-02483-z

Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain

Wheatley, Adam K.; Pymm, Phillip; Esterbauer, Robyn; Dietrich, Melanie H.; Lee, Wen Shi; Drew, Damien; Kelly, Hannah G.; Chan, Li Jin; Mordant, Francesca L.; Black, Katrina A.; Adair, Amy; Tan, Hyon Xhi; Juno, Jennifer A.; Wragg, Kathleen M.; Amarasena, T

(2021), CELL REP, 37(2, 109822), 1-e11

DOI: 10.1016/j.celrep.2021.109822

The Impact of the COVID-19 Pandemic on People Living with HIV in Victoria, Australia

Weerasuria, Mihiri P.; Ko, Christy; Ehm, Adam; O'Bryan, Jessica; McMahon, James; Woolley, Ian; Hoy, Jennifer F.; Lau, Jillian S.Y.

(2021), AIDS RES HUM RETROV, 37(4), 322-328

DOI: 10.1089/aid.2021.0007

Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity

Vu, Mai N.; Kelly, Hannah G.; Tan, Hyon Xhi; Juno, Jennifer A.; Esterbauer, Robyn; Davis, Thomas P.; Truong, Nghia P.; Wheatley, Adam K.; Kent, Stephen J.

(2021), ADV HEALTHC MATER, 10(10), 2002142

DOI: 10.1002/adhm.202002142

Context-aware genomic surveillance reveals hidden transmission of a carbapenemase-producing Klebsiella pneumoniae

Viehweger, Adrian; Blumenscheit, Christian; Lippmann, Norman; Wyres, Kelly L.; Brandt, Christian; Hans, Jörg B.; Hölzer, Martin; Irber, Luiz; Gatermann, Sören; Lübbert, Christoph; Pletz, Mathias W.; Holt, Kathryn E.; König, Brigitte

(2021), MICROBIOL GENOMICS, 7(12), 741

DOI: 10.1099/mgen.0.000741

Staphylococcus aureus Skin and Soft Tissue Infection Recurrence Rates in Outpatients

Vella, Venanzio; Galgani, Ilaria; Polito, Letizia; Arora, Ashwani Kumar; Creech, C. Buddy; David, Michael Z.; Lowy, Franklin D.; Macesic, Nenad; Ridgway, Jessica P.; Uhlemann, Anne Catrin; Bagnoli, Fabio

(2021), CLIN INFECT DIS, 73(5), E1045-E1053

DOI: 10.1093/cid/ciaa1717

Collateral Sensitivity to β-Lactam Drugs in Drug-Resistant Tuberculosis Is Driven by the Transcriptional Wiring of BlaI Operon Genes

Trigos, A. S.; Goudey, B. W.; Bedő, J.; Conway, T. C.; Faux, N. G.; Wyres, K. L.

(2021), MSPHERE, 6(3), e0024521

DOI: 10.1128/mSphere.00245-21

Pharmacodynamics of ceftazidime plus tobramycin combination dosage regimens against hypermutable Pseudomonas aeruginosa isolates at simulated epithelial lining fluid concentrations in a dynamic in vitro infection model

Tait, Jessica R.; Bilal, Hajira; Kim, Tae Hwan; Oh, Abigail; Peleg, Anton Y.; Boyce, John D.; Oliver, Antonio; Bergen, Phillip J.; Nation, Roger L.; Landersdorfer, Cornelia B.

(2021), J GLOB ANTIMICROB RE, 26, 55-63

DOI: 10.1016/j.jgar.2021.04.021

Population-based analysis of the epidemiological features of COVID-19 epidemics in Victoria, Australia, January 2020 – March 2021, and their suppression through comprehensive control strategies

Sullivan, Sheena G.; Brotherton, Julia M.L.; Lynch, Brigid M.; Cheung, Allison; Lydeamore, Michael; Stevenson, Mark; Firestone, Simon; Canevari, Jose; Nguyen, Huu Nghia Joey; Carville, Kylie S.; Clothier, Hazel J.; Goldsmith, Jessie; Tenneti, Naveen; Barn

(2021), Lancet Regional Health-Western Pacific, 17, 100297

DOI: 10.1016/j.lanwpc.2021.100297

Acceptability of Injectable Antiretroviral Therapy in Australian Travelers With HIV

Spring, Stephanie; O'Bryan, Jessica; McMahon, James; Woolley, Ian

(2021), JAIDS-J ACQ IMM DEF, 86(1), e13-e15

DOI: 10.1097/QAI.0000000000002501

Follow-up and Clinical Outcomes of Human Immunodeficiency Virus (HIV)-Exposed Infants in A Low-Prevalence Setting in A Multidisciplinary Model of Care in Australia

Shepherd, Kathryn; Giles, Michelle; Blyth, Karen; O'keeffe, Fiona; Bordun, Louise; Connell, Tom G.; Bryant, Penelope A.

(2021), J PEDIAT INF DIS SOC, 10(1), 14-21

DOI: 10.1093/jpids/piaa010

Genome-wide analysis provides a deeper understanding of the population structure of the Salmonella enterica serotype Paratyphi B complex in Bangladesh

Rahman, Sadia Isfat Ara; Taylor-Brown, Alyce; Khanam, Farhana; Khan, Ashraful Islam; Horesh, Gal; Dyson, Zoe A.; Begum, Yasmin Ara; Chowdhury, Emran Kabir; Qadri, Firdausi; Dougan, Gordon; Thomson, Nicholas R.

(2021), MICROBIOL GENOMICS, 7(9),

DOI: 10.1099/mgen.0.000617