Clinical Haematology research

Our Clinical Haematology service is affiliated with the laboratory and clinical research conducted by the Australian Centre for Blood Diseases (ACBD).

ACBD is a leading national and international blood diseases centre with recognised research, treatment, and educational programs for blood diseases. ACBD is affiliated with The Alfred, Monash University, Eastern Health and Southern Health.

Research is divided into two main groups:

  • Blood cancers and stem cells
  • Haemostasis and thrombosis

Australian Centre for Blood Diseases

For more information about our research groups, teaching and education programs, visit the Australian Centre for Blood Diseases.

Publications

UHRF1/UBE2L6/UBR4-mediated ubiquitination regulates EZH2 abundance and thereby melanocytic differentiation phenotypes in melanoma

Kuser Abali, Gamze; Zhang, Youfang; Szeto, Pacman; Zhao, Peinan; Masoumi Moghaddam, Samar; Fedele, Clare Grace; Leece, Isobel Anne Murrell; Huang, Cheng; Cheung, Yi Ting; Ameratunga, Malaka; Noguchi, Fumihito; Andrews, Miles Cameron Gregory; Wong, Nichola

(2023), Oncogene, 42(17), 1360–1373

DOI: 10.1038/s41388-023-02631-8

Prehospital Tranexamic Acid for Severe Trauma

PATCH-Trauma Investigators and the ANZICs Clinical Trials Group; Gruen, R; Mitra, B; Bernard, SA; McArthur, C; Burns, B; Gantner, D; Maegele, MG.; Cameron, P; Dicker, BL.; Forbes, AB; Hurford, S.; Martin, CA; Mazur, SM; Medcalf RL; Murray LJ, Myles PS, Ng SJ, Pitt V, Rashford S,... Young PJ

(2023), New England Journal of Medicine, 389(2), 127-136

DOI: 10.1056/NEJMoa2215457

Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes

Sparbier, Christina E.; Gillespie, Andrea; Gomez, Juliana; Kumari, Nishi; Motazedian, Ali; Chan, Kah Lok; Bell, Charles C.; Gilan, Omer; Chan, Yih Chih; Popp, Sarah; Gough, Daniel James; Eckersley-Maslin, Melanie A.; Dawson, Sarah-Jane; Lehner, Paul J.; S

(2023), Nature Cell Biology, 25(2), 258-272

DOI: 10.1038/s41556-022-01056-x

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