Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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The effect of CPAP in normalizing daytime sleepiness, quality of life, and neurocognitive function in patients with moderate to severe OSA

Antic NA, Catcheside P, Buchan C, Hensley M, Naughton MT, Rowland S, Williamson B, Windler S, McEvoy RD

(2011), Sleep, 34(1), 111-9

Methods to measure the kinetics of protease inhibition by serpins

Horvath AJ, Lu BG, Pike RN, Bottomley SP

(2011), Methods Enzymol, 501, 223-35

Plasminogen activator inhibitor type 2: still an enigmatic serpin but a model for gene regulation

Medcalf R

(2011), Methods Enzymol, 499, 105-34

Phosphatidylinositol(4,5)bisphosphate coordinates actin-mediated mobilization and translocation of secretory vesicles to the plasma membrane of chromaffin cells

Wen PJ, Osborne SL, Zanin M, Low PC, Wang HT, Schoenwaelder SM, Jackson SP, Wedlich-Söldner R, Vanhaesebroeck B, Keating DJ, Meunier FA

(2011), Nat Commun, 2, 491

Prothrombin complex concentrates used alone in urgent reversal of warfarin anticoagulation

Tran H, Collecutt M, Whitehead S, Salem HH

(2011), Intern Med J, 41(4), 337-43

Structural and hydrodynamic simulation of an acute stenosis-dependent thrombosis model in mice

Tovar-Lopez FJ, Rosengarten G, Khoshmanesh K, Westein E, Jackson SP, Nesbitt WS, Mitchell A

(2011), J Biomech, 44(6), 1031-9

Allelic imbalance of tissue-type plasminogen activator (t-PA) gene expression in human brain tissue

Tjarnlund-Wolf A, Hultman K, Curtis MA, Faull RL, Medcalf RL, Jern C

(2011), Thromb Haemost, 105(6), 945-53

Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF-ΚB pathway

Stankovic S, Gugasyan R, Kyparissoudis K, Grumont R, Banerjee A, Tsichlis P, Gerondakis S, Godfrey DI

(2011), Immunol Cell Biol, 89(2), 294-303

Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

Schoenwaelder SM, Jarman KE, Gardiner EE, Hua M, Qiao J, White MJ, Josefsson EC, Alwis I, Ono A, Willcox A, Andrews RK, Mason KD, Salem HH, Huang DC, Kile BT, Roberts AW, Jackson SP

(2011), Blood, 118(6), 1663-74

Managing multiple myeloma in the elderly: are we making progress?

Quach H, Prince HM, Spencer A

(2011), Expert Rev Hematol, 4(3), 301-15

Asparaginase in the management of adult acute lymphoblastic leukaemia: is it used appropriately?

Patil S, Coutsouvelis J, Spencer A

(2011), Cancer Treat Rev, 37(3), 202-7

Rapid platelet accumulation leading to thrombotic occlusion

Para A, Bark D, Lin A, Ku D

(2011), Ann Biomed Eng, 39(7), 1961-71

Personalized therapy in multiple myeloma according to patient age and vulnerability: a report of the European Myeloma Network (EMN)

Palumbo A, Bringhen S, Ludwig H, Dimopoulos MA, Bladé J, Mateos MV, Rosiñol L, Boccadoro M, Cavo M, Lokhorst H, Zweegman S, Terpos E, Davies F, Driessen C, Gimsing P, Gramatzki M, Hàjek R, Johnsen HE, Leal Da Costa F, Sezer O, Spencer A, Beksac M, Morgan

(2011), Blood, 118(17), 4519-29

Thrombin-induced activation of astrocytes in mixed rat hippocampal cultures is inhibited by soluble thrombomodulin

Niego B, Samson AL, Petersen KU, Medcalf RL

(2011), Brain Res, 1381, 38-51

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation

Nguyen NY, Maxwell MJ, Ooms LM, Davies EM, Hilton AA, Collinge JE, Hilton DJ, Kile BT, Mitchell CA, Hibbs ML, Jane SM, Curtis DJ

(2011), Blood, 117(20), 5362-71

The role of the bone marrow microenvironment in multiple myeloma

Monaghan K, Spencer A

(2011), Eur J Clin Med Oncol, 3(2), 8

CYT997 causes apoptosis in human multiple myeloma

Monaghan K, Khong T, Smith G, Spencer A

(2011), Invest New Drugs, 29(2), 232-5

Antiplatelet drugs, anticoagulants and elective surgery

Merriman E, Tran H

(2011), Aust Prescr, 34(5), 139-43

Plasminogen activation-based thrombolysis for ischaemic stroke: the diversity of targets may demand new approaches

Medcalf RL

(2011), Curr Drug Targets, 12(12), 1772-81

The anti-leukemic effect and molecular mechanisms of novel hydroxamate and benzamide histone deacetylase inhibitors with 5-aza-cytidine

Liu HB, Mayes PA, Perlmutter P, McKendrick JJ, Dear AE

(2011), Int J Oncol, 38(5), 1421-5

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