Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Targeting HSP 90 induces apoptosis and inhibits critical survival and proliferation pathways in multiple myeloma

Khong T, Spencer A

(2011), Mol Cancer Ther, 10(10), 1909-17

The role of platelets in atherothrombosis

Kaplan ZS, Jackson SP

(2011), Hematology Am Soc Hematol Educ Program, 2011, 51-61

Arterial thrombosis - insidious, unpredictable and deadly

Jackson SP

(2011), Nat Med, 17(11), 1423-36

PPARγ-independent thiazolidinedione-mediated inhibition of NUR77 expression in vascular endothelial cells

Hu Y, Liu HB, Simpson RW, Dear AE

(2011), J Endocrinol, 208(1), R1-7

Collagen surfaces to measure thrombus formation under flow: possibilities for standardization

Heemskerk JW, Sakariassen KS, Zwaginga JJ, Brass LF, Jackson SP, Farndale RW; Biorheology Subcommittee of the SSC of the ISTH

(2011), J Thromb Haemost, 9(4), 856-8

A sensitized RNA interference screen identifies a novel role for the PI3K p110γ isoform in medulloblastoma cell proliferation and chemoresistance

Guerreiro AS, Fattet S, Kulesza DW, Atamer A, Elsing AN, Shalaby T, Jackson SP, Schoenwaelder SM, Grotzer MA, Delattre O, Arcaro A

(2011), Mol Cancer Res, 9(7), 925-35

c-Rel controls multiple discrete steps in the thymic development of Foxp3+ CD4 regulatory T cells

Grigoriadis G, Vasanthakumar A, Banerjee A, Grumont R, Overall S, Gleeson P, Shannon F, Gerondakis S

(2011), PLoS One, 6(10), e26851

Persistent complement-dependent anti-AnWj in a lymphoproliferative disorder: a case study and review

Grigoriadis G, Condon J, Green K, Anderson MA, Borosak M, Wood E

(2011), Immunohematology, 27(3), 83-8

NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights

Gough SM, Slape CI, Aplan PD

(2011), Blood, 118(24), 6247-57

A GLP-1 receptor agonist liraglutide inhibits endothelial cell dysfunction and vascular adhesion molecule expression in an ApoE-/- mouse model

Gaspari T, Liu H, Welungoda I, Hu Y, Widdop RE, Knudsen LB, Simpson RW, Dear AE

(2011), Diab Vasc Dis Res, 8(2), 117-24

A synthetic haemoglobin-based oxygen carrier and the reversal of cardiac hypoxia secondary to severe anaemia following trauma

Fitzgerald MC, Chan JY, Ross AW, Liew SM, Butt WW, Baguley D, Salem HH, Russ MK, Deasy C, Martin KE, Mathew JK, Rosenfeld JV

(2011), Med J Aust, 194(9), 471-3

The planar cell polarity pathway in vertebrate epidermal development, homeostasis and repair

Dworkin S, Jane SM, Darido C

(2011), Organogenesis, 7(3), 202-8

Clopidogrel Resistance: case reports of CYP2C19 gene variants in suspected coronary stent thrombosis

Dick RJ, Dear AE, Byron KA

(2011), Heart Lung Circ, 20(10), 657-8

The catalytic class I(A) PI3K isoforms play divergent roles in breast cancer cell migration

De Laurentiis A, Pardo OE, Palamidessi A, Jackson SP, Schoenwaelder SM, Reichmann E, Scita G, Arcaro A

(2011), Cell Signal, 23(3), 529-41

Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis

Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM

(2011), Cancer Cell, 20(5), 635-48

High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction

Cranmer SL, Ashworth KJ, Yao Y, Berndt MC, Ruggeri ZM, Andrews RK, Jackson SP

(2011), Blood, 117(9), 2718-27

Critical role of cRel subunit of NF-ΚB in sepsis survival

Courtine E, Pène F, Cagnard N, Toubiana J, Fitting C, Brocheton J, Rousseau C, Gerondakis S, Chiche JD, Ouaaz F, Mira JP

(2011), Infect Immun, 79(5), 1848-54

The NF-ΚB transcription factor c-Rel is required for Th17 effector cell development in experimental autoimmune encephalomyelitis

Chen G, Hardy K, Pagler E, Ma L, Lee S, Gerondakis S, Daley S, Shannon MF

(2011), J Immunol, 187(9), 4483-91

The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity

Boglev Y, Wilanowski T, Caddy J, Parekh V, Auden A, Darido C, Hislop NR, Cangkrama M, Ting SB, Jane SM

(2011), Dev Biol, 349(2), 512-22

TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets

Arthur JF, Shen Y, Gardiner EE, Coleman L, Murphy D, Kenny D, Andrews RK, Berndt MC

(2011), J Thromb Haemost, 9(1), 163-72

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