Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Safety and Efficacy of Tenecteplase in Older Patients with Large Vessel Occlusion

Yogendrakumar, Vignan; Churilov, Leonid; Mitchell, Peter J; Kleinig, Timothy J; Yassi, Nawaf; Thijs, Vincent; Wu, Teddy Y; Shah, Darshan G; Ng, Felix C; Dewey, Helen M; Wijeratne, Tissa; Yan, Bernard; Desmond, Patricia M; Parsons, Mark W; Donnan,

(2022), NEUROLOGY, 98(12), E1292-E1301

DOI: 101212/WNL0000000000013302

Serious Cardiac Arrhythmias Detected by Subcutaneous Long-term Cardiac Monitors in Patients With Drug-Resistant Epilepsy

Sivathamboo, Shobi; Liu, Zining; Sutherland, Fiona; Minato, Erica; Casillas-Espinosa, Pablo; Jones, Nigel Charles; Todaro, Marian; Seneviratne, Udaya; Cahill, Varduhi; Yerra, Raju; French, Christopher R; Nicolo, John-Paul; Perucca, Piero; Kwan, Patrick;

(2022), NEUROLOGY, 98(19), e1923-e1932

DOI: 101212/WNL0000000000200173

Early and progressive dysfunction revealed by in vivo neurite imaging in the rNLS8 TDP-43 mouse model of ALS

Zamani, Akram; Walker, Adam K; Rollo, Ben; Ayers, Katie L; Farah, Raysha; O'Brien, Terence J; Wright, David K

(2022), NEUROIMAGE-CLIN, 34, 103016

DOI: 101016/jnicl2022103016

Brain tissue microstructural and free-water composition 13 years after very preterm birth

Kelly, Claire; Dhollander, Thijs; Harding, Ian H; Khan, Wasim; Beare, Richard; Cheong, Jeanie LY; Doyle, Lex W; Seal, Marc; Thompson, Deanne K; Inder, Terrie E; Anderson, Peter J

(2022), NEUROIMAGE, 254, 119168

DOI: 101016/jneuroimage2022119168

Cortical thinning 3 years after ischaemic stroke is associated with cognitive impairment and APOE e4

Salah Khlif, Mohamed; Egorova-Brumley, Natalia; Bird, Laura J; Werden, Emilio; Brodtmann, Amy

(2022), NEUROIMAGE-CLIN, 36, 103200

DOI: 101016/jnicl2022103200

Characterising seizure development, behavioural comorbidities and neuroinflammation in a self-sustained electrical status epilepticus model of mesial temporal lobe epilepsy in C57BL/6J mice

Thergarajan, Peravina; Hudson, Matthew R; Carmichael, Irena; Clasadonte, Jérôme; Dedeurwaerdere, Stefanie; O'Brien, Terence J; Jones, Nigel C; Ali, Idrish

(2022), NEUROBIOL DIS, 168, 105688

DOI: 101016/jnbd2022105688

Treatment with Multiple Therapeutic Classes of Medication Is Associated with Survival after Stroke

Kilkenny, Monique F; Olaiya, Muideen T; Dalli, Lachlan L; Kim, Joosup; Andrew, Nadine E; Sanfilippo, Frank M; Thrift, Amanda G; Nelson, Mark; Pearce, Christopher; Sanders, Lauren; Dewey, Helen; Clissold, Benjamin; Grimley, Rohan; Cadilhac, Dominique

(2022), NEUROEPIDEMIOLOGY, 56(1), 66-74

DOI: 101159/000520823

Interictal and seizure-onset EEG patterns in malformations of cortical development: A systematic review

Shakhatreh, Lubna; Janmohamed, Mubeen; Baker, Ana Antonic; Willard, Anna; Laing, Joshua; Rychkova, Maria; Chen, Zhibin; Kwan, Patrick; O'Brien, Terence J; Perucca, Piero

(2022), NEUROBIOL DIS, 174, 105863

DOI: 101016/jnbd2022105863

Hypothalamic effective connectivity at rest is associated with body weight and energy homeostasis

Voigt, Katharina; Andrews, Zane B; Harding, Ian H; Razi, Adeel; Verdejo-García, Antonio

(2022), NETW NEUROSCI, 6(4), 1316-1333

DOI: 101162/netn_a_00266

Establishment and recall of SARS-CoV-2 spike epitope-specific CD4+ T cell memory

Wragg, Kathleen M; Lee, Wen Shi; Koutsakos, Marios; Tan, Hyon-Xhi; Amarasena, Thakshila; Reynaldi, Arnold; Gare, Grace; Konstandopoulos, Penny; Field, Kirsty R; Esterbauer, Robyn; Kent, Helen E; Davenport, Miles P; Wheatley, Adam K; Kent, Stephen J;

(2022), NAT IMMUNOL, 23(5), 768-780

DOI: 101038/s41590-022-01175-5

Disentangling the relative importance of T cell responses in COVID-19

Kent, Stephen J; Khoury, David S; Reynaldi, Arnold; Juno, Jennifer A; Wheatley, Adam K; Stadler, Eva; John Wherry, E; Triccas, James; Sasson, Sarah C; Cromer, Deborah; Davenport, Miles P

(2022), NAT REV IMMUNOL, 22(6), 387-397

DOI: 101038/s41577-022-00716-1

Time is of the essence for vaccine success

Quast, Isaak; Tarlinton, David

(2022), NAT IMMUNOL, 23(11), 1517–1519

DOI: 101038/s41590-022-01347-3

Immunological dysfunction persists for 8 months following initial mild-to-moderate SARS-CoV-2 infection

Phetsouphanh, Chansavath; Darley, David R; Wilson, Daniel B; Howe, Annett; Munier, C Mee Ling; Patel, Sheila K; Juno, Jennifer A; Burrell, Louise M; Kent, Stephen J; Dore, Gregory J; Kelleher, Anthony D; Matthews, Gail V

(2022), NAT IMMUNOL, 23(2), 210-216

DOI: 101038/s41590-021-01113-x

Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection

Di Pietro, Andrea; Polmear, Jack; Cooper, Lucy; Damelang, Timon; Hussain, Tabinda; Hailes, Lauren; O’Donnell, Kristy; Udupa, Vibha; Mi, Tian; Preston, Simon; Shtewe, Areen; Hershberg, Uri; Turner, Stephen J; La Gruta, Nicole L; Chung, Amy W; Tarlinton,

(2022), NAT IMMUNOL, 23(1), 86-98

DOI: 101038/s41590-021-01077-y

Distinct increase in antimicrobial resistance genes among Escherichia coli during 50 years of antimicrobial use in livestock production in China

Yang, Lu; Shen, Yingbo; Jiang, Junyao; Wang, Xueyang; Shao, Dongyan; Lam, Margaret MC; Holt, Kathryn E; Shao, Bing; Wu, Congming; Shen, Jianzhong; Walsh, Timothy R; Schwarz, Stefan; Wang, Yang; Shen, Zhangqi

(2022), NAT FOOD, 3(3), 197-205

DOI: 101038/s43016-022-00470-6

A Shigella sonnei clone with extensive drug resistance associated with waterborne outbreaks in China

Qiu, Shaofu; Liu, Kangkang; Yang, Chaojie; Xiang, Ying; Min, Kaiyuan; Zhu, Kunpeng; Liu, Hongbo; Du, Xinying; Yang, Mingjuan; Wang, Ligui; Sun, Yong; Zhou, Haijian; Mahe, Muti; Zhao, Jiayong; Li, Shijun; Yu, Deshan; Hawkey, Jane; Holt, Kathryn E; Baker,

(2022), NAT COMMUN, 13(1), 7365

DOI: 101038/s41467-022-35136-1

Deep proteomic profiling unveils arylsulfatase A as a non-alcoholic steatohepatitis inducible hepatokine and regulator of glycemic control

Montgomery, Magdalene K; Bayliss, Jacqueline; Nie, Shuai; De Nardo, William; Keenan, Stacey N; Miotto, Paula M; Karimkhanloo, Hamzeh; Huang, Cheng; Schittenhelm, Ralf B; Don, Anthony S; Ryan, Andrew; Williamson, Nicholas A; Ooi, Geraldine J; Brown,

(2022), NAT COMMUN, 13(1), 1259

DOI: 101038/s41467-022-28889-2

Paratype: a genotyping tool for Salmonella Paratyphi A reveals its global genomic diversity

Tanmoy, Arif M; Hooda, Yogesh; Sajib, Mohammad SI; da Silva, Kesia E; Iqbal, Junaid; Qamar, Farah N; Luby, Stephen P; Dougan, Gordon; Dyson, Zoe A; Baker, Stephen; Garrett, Denise O; Andrews, Jason R; Saha, Samir K; Saha, Senjuti

(2022), NAT COMMUN, 13(1), 7912

DOI: 101038/s41467-022-35587-6

Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression

Larivière, Sara; Royer, Jessica; Rodríguez-Cruces, Raúl; Paquola, Casey; Caligiuri, Maria Eugenia; Gambardella, Antonio; Concha, Luis; Keller, Simon S; Cendes, Fernando; Yasuda, Clarissa L; Bonilha, Leonardo; Gleichgerrcht, Ezequiel; Focke, Niels K; Do

(2022), NAT COMMUN, 13(1), 4320

DOI: 101038/s41467-022-31730-5

SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity

Zhang, Wuji; Chua, Brendon Y; Selva, Kevin J; Kedzierski, Lukasz; Ashhurst, Thomas M; Haycroft, Ebene R; Shoffner-Beck, Suzanne K; Hensen, Luca; Boyd, David F; James, Fiona; Mouhtouris, Effie; Kwong, Jason C; Chua, Kyra YL; Drewett, George; Copae

(2022), NAT COMMUN, 13(1), 2774

DOI: 101038/s41467-022-30088-y

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