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Alfred Health research outcomes are published in a wide range of peer reviewed journals.
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Publication Details
A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen
Conway AJ, Brown FC, Fullinfaw RO, Kile BT, Jane SM, Curtis DJ
(2017), Dis Model Mech, 10(8), 1005-13
DOI: 10.1242/dmm.029116
Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression
Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin GH, Wang J, Ng V, Xia B, Witkowski MT, Mitchell-Flack M, Grillo I, Bakogianni S, Ndiaye-Lobry D, MartÃn MT, Guillamot M, Banh RS, Xu M, Figueroa ME, Dickins RA, Abdel-Wahab O, Park CY, Tsirigos A, Neel BG, Aifantis I
(2017), Cell, 170(6), 1079-95.e20
Generation of an inducible mouse model to reversibly silence Stat3
Alorro MG, Pierce TP, Eissmann MF, Dijkstra C, Dickins RA, Ernst M, Buchert M, Masson F
(2017), Genesis, 55(4), e23023
DOI: 10.1002/dvg.23023
Self-Assembled Nanoparticles from Phenolic Derivatives for Cancer Therapy
Dai Y, Guo J, Wang TY, Ju Y, Mitchell AJ, Bonnard T, Cui J, Richardson JJ, Hagemeyer CE, Alt K, Caruso F
(2017), Adv Healthc Mater, 6(16), 1700467
Application of a strain rate gradient microfluidic device to von Willebrand's disease screening
Brazilek RJ, Tovar-Lopez FJ, Wong AKT, Tran H, Davis AS, McFadyen JD, Kaplan Z, Chunilal S, Jackson SP, Nandurkar H, Mitchell A, Nesbitt WS
(2017), Lab Chip, 17(15), 2595-608
DOI: 10.1039/c7lc00498b
Decreased levels of platelet-derived soluble glycoprotein VI detected prior to the first diagnosis of coronary artery disease in HIV-positive individuals.
Trevillyan JM, Gardiner EE, Andrews RK, Maisa A, Hearps AC, Al-Tamimi M, Crowe SM, Hoy JF
(2017), Platelets, 28(3), 301-4
Platelet hyperreactivity in diabetes: focus on GPVI signaling-are useful drugs already available?
Arthur JF, Jandeleit-Dahm K, Andrews RK
(2017), Diabetes, 66(1), 7-13
DOI: 10.2337/db16-1098
High-density lipoprotein delivered after myocardial infarction increases cardiac glucose uptake and function in mice
Heywood SE, Richart AL, Henstridge DC, Alt K, Kiriazis H, Zammit C, Carey AL, Kammoun HL, Delbridge LM, Reddy M, Chen YC, Du XJ, Hagemeyer CE, Febbraio MA, Siebel AL, Kingwell BA
(2017), Sci Transl Med, 9(411), eaam6084
Shear-sensitive nanocapsule drug release for site-specific inhibition of occlusive thrombus formation
Molloy CP, Yao Y, Kammoun H, Bonnard T, Hoefer T, Alt K, Tovar-Lopez F, Rosengarten G, Ramsland PA, van der Meer AD, van den Berg A, Murphy AJ, Hagemeyer CE, Peter K, Westein E
(2017), J Thromb Haemost, 15(5), 972-82
DOI: 10.1111/jth.13666
Pharmacokinetics and safety of carfilzomib in patients with relapsed multiple myeloma and end-stage renal disease (ESRD): an open-label, single-arm, phase I study
Quach H, White D, Spencer A, Ho PJ, Bhutani D, White M, Inamdar S, Morris C, Ou Y, Gyger M
(2017), Cancer Chemother Pharmacol, 79(6), 1067-76
Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation
Stone RM, Mandrekar SJ, Sanford BL, Laumann K, Geyer S, Bloomfield CD, Thiede C, Prior TW, Dàhner K, Marcucci G, Lo-Coco F, Klisovic RB, Wei A, Sierra J, Sanz MA, Brandwein JM, de Witte T, Niederwieser D, Appelbaum FR, Medeiros BC, Tallman MS, Krauter J, Schlenk RF, Ganser A, Serve H, Ehninger G, Amadori S, Larson RA, Dàhner H
(2017), N Engl J Med, 377(5), 454-64
An individualised risk-adapted protocol of pre- and post transplant zoledronic acid reduces bone loss after allogeneic stem cell transplantation: results of a phase II prospective trial
Grigg A, Butcher B, Khodr B, Bajel A, Hertzberg M, Patil S, D'Souza AB, Ganly P, Ebeling P, Wong E
(2017), Bone Marrow Transplant, 52(9), 1288-93
DOI: 10.1038/bmt.2017.108
Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results
Hughes TP, Leber B, Cervantes F, Spector N, Pasquini R, Clementino NCD, Schwarer AP, Dorlhiac-Llacer PE, Mahon FX, Rea D, Guerci-Bresler A, Kamel-Reid S, Bendit I, Acharya S, Glynos T, Dalal D, Branford S, Lipton JH
(2017), Leukemia, 31(11), 2529-31
DOI: 10.1038/leu.2017.247
Platelet-targeted delivery of peripheral blood mononuclear cells to the ischemic heart restores cardiac function after ischemia-reperfusion injury
Ziegler M, Wang X, Lim B, Leitner E, Klingberg F, Ching V, Yao Y, Huang D, Gao XM, Kiriazis H, Du XJ, Haigh JJ, Bobik A, Hagemeyer CE, Ahrens I, Peter K
(2017), Theranostics, 7(13), 3192-206
DOI: 10.7150/thno.19698
Development of a novel strategy to target CD39 antithrombotic activity to the endothelial-platelet microenvironment in kidney ischemia-reperfusion injury
Sashindranath M, Dwyer KM, Dezfouli S, Selan C, Crikis S, Lu B, Yuan Y, Hickey MJ, Peter K, Robson SC, Cowan PJ, Nandurkar HH
(2017), Purinergic Signal, 13(2), 259-65
Novel thrombolytic drug based on thrombin cleavable microplasminogen coupled to a single-chain antibody specific for activated GPIIb/IIIa
Bonnard T, Tennant Z, Niego B, Kanojia R, Alt K, Jagdale S, Law LS, Rigby S, Medcalf RL, Peter K, Hagemeyer CE
(2017), J Am Heart Assoc, 6(2), e004535
An evidence-based approach to myeloma bone disease
Bingham N, Reale A, Spencer A
(2017), Curr Hematol Malig Rep, 12(2), 109-18
The incidence and natural history of dasatinib complications in the treatment of chronic myeloid leukemia
Fox LC, Cummins KD, Costello B, Yeung D, Cleary R, Forsyth C, Tatarczuch M, Burbury K, Motorna O, Shortt J, Fleming S, McQuillan A, Schwarer A, Harrup R, Holmes A, Ratnasingam S, Chan KL, Hsu WH, Ashraf A, Putt F, Grigg A
(2017), Blood Adv, 1(13), 802-11
Neutrophil macroaggregates promote widespread pulmonary thrombosis after gut ischemia
Yuan Y, Alwis I, Wu MCL, Kaplan Z, Ashworth K, Bark D Jr, Pham A, Mcfadyen J, Schoenwaelder SM, Josefsson EC, Kile BT, Jackson SP
(2017), Sci Transl Med, 9(409), eaam5861
Anti-fibrinolytics
Draxler DF, Medcalf RL, Gruen RL
(2016), In: Gonzalez E, Moore HB, Moore EE (eds), Trauma Induced Coagulopathy, Springer International Publishing,