Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Augmentation with pre-emptive macrogol-based osmotic laxative does not significantly improve standard bowel preparation in unselected patients

Mangira, Dileep; Ket, Shara; Dwyer, Jeremy; Secomb, Robyn; Reynolds, John; Brown, Gregor

(2019), JGH Open, 3(5), 374-380.

DOI: 10.1002/jgh3.12170

Beneficial response to mycophenolate mofetil by patients with autoimmune hepatitis who have failed standard therapy, is predicted by older age and lower immunoglobulin G and INR levels

Nicoll, Amanda J.; Roberts, Stuart K.; Lim, Ricky; Mitchell, Joanne; Weltman, Martin; George, Jacob; Wigg, Alan; Stuart, Katherine; Gow, Paul; MacQuillan, Gerry; Tse, Edmund; Levy, Miriam; Sood, Siddharth; Zekry, Amany; Cheng, Wendy; Mitchell, Jonathan; Skoien, Richard; Sievert, William; Strasser, Simone I.; McCaughan, Geoffrey W.; ,

(2019), ALIMENT PHARM THER, 49(10), 1314-1322.

DOI: 10.1111/apt.15248

Higher Mucosal Healing with Tumor Necrosis Factor Inhibitors in Combination with Thiopurines Compared to Methotrexate in Crohn’s Disease

Vasudevan, Abhinav; Raghunath, Ajay; Anthony, Shane; Scanlon, Cian; Sparrow, Miles P.; Gibson, Peter R.; van Langenberg, Daniel R.

(2019), DIGEST DIS SCI, 64(6), 1622-1631.

DOI: 10.1007/s10620-018-5422-8

The intestinal vitamin D receptor in inflammatory bowel disease

Garg, Mayur; Royce, Simon G.; Tikellis, Chris; Shallue, Claire; Sluka, Pavel; Wardan, Hady; Hosking, Patrick; Monagle, Shaun; Thomas, Merlin; Lubel, John S.; Gibson, Peter R.

(2019), THER ADV GASTROENTER, (12), 1-15.

DOI: 10.1177/1756284818822566

Multiunit cluster firing patterns of piriform cortex and mediodorsal thalamus in absence epilepsy

Young, James C.; Nasser, Helen M.; Casilla-Espinosa, Pablo; O'Brien, Terence J.; Jackson, Graeme D.; Paolini, Antonio G.

(2019), EPILEPSY BEHAV, (97), 229-243

DOI: 10.1016/j.yebeh.2019.05.032

Repeated mild traumatic brain injuries induce persistent changes in plasma protein and magnetic resonance imaging biomarkers in the rat

Wright, David K.; Brady, Rhys D.; Kamnaksh, Alaa; Trezise, Jack; Sun, Mujun; McDonald, Stuart J.; Mychasiuk, Richelle; Kolbe, Scott C.; Law, Meng; Johnston, Leigh A.; O'Brien, Terence J.; Agoston, Denes V.; Shultz, Sandy R.

(2019), SCI REP-UK, 9(1), 14626

DOI: 10.1038/s41598-019-51267-w

Targeting high-mobility group box protein 1 (HMGB1) in pediatric traumatic brain injury

Webster, Kyria M.; Shultz, Sandy R.; Ozturk, Ezgi; Dill, Larissa K.; Sun, Mujun; Casillas-Espinosa, Pablo; Jones, Nigel C.; Crack, Peter J.; O'Brien, Terence J.; Semple, Bridgette D.

(2019), EXP NEUROL, 320, 112979

DOI: 10.1016/j.expneurol.2019.112979

Sleep-disordered breathing among patients admitted for inpatient video-EEG monitoring

Sivathamboo, Shobi; Farrand, Sarah; Chen, Zhibin; White, Elise J.; Pattichis, Andrew Andreas; Hollis, Callum; Carino, John; Roberts, Caitlin J.; Minogue, Thomas; Jones, Nigel C.; Yerra, Raju; French, Christopher; Perucca, Piero; Kwan, Patrick; Velakoulis, Dennis; O'Brien, Terence J.; Goldin, Jeremy

(2019), NEUROLOGY, 92(3), e194-e204

DOI: 10.1212/WNL.0000000000006776

Harmonization of pipeline for detection of HFOs in a rat model of post-traumatic epilepsy in preclinical multicenter study on post-traumatic epileptogenesis

Santana-Gomez, Cesar; Andrade, Pedro; Hudson, Matthew R.; Paananen, Tomi; Ciszek, Robert; Smith, Gregory; Ali, Idrish; Rundle, Brian K.; Ndode-Ekane, Xavier Ekolle; Casillas-Espinosa, Pablo M.; Immonen, Riikka; Puhakka, Noora; Jones, Nigel; Brady, Rhys D.; Perucca, Piero; Shultz, Sandy R.; Pitkänen, Asla; O'Brien, Terence J.; Staba, Richard

(2019), EPILEPSY RES, 156, 106110

DOI: 10.1016/j.eplepsyres.2019.03.008

Epilepsy and seizure-related deaths

Panelli, Rosemary J.; O'Brien, Terence J.

(2019), EPILEPSY BEHAV, (98), 266-272

DOI: 10.1016/j.yebeh.2019.07.003

Harmonization of lateral fluid-percussion injury model production and post-injury monitoring in a preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis

Ndode-Ekane, Xavier Ekolle; Santana-Gomez, Cesar; Casillas-Espinosa, Pablo M.; Ali, Idrish; Brady, Rhys D.; Smith, Gregory; Andrade, Pedro; Immonen, Riikka; Puhakka, Noora; Hudson, Matthew R.; Braine, Emma L.; Shultz, Sandy R.; Staba, Richard J.; O'Brien, Terence J.; Pitkänen, Asla

(2019), EPILEPSY RES, (151), 7-16

DOI: 10.1016/j.eplepsyres.2019.01.006

The utility of an automated and ambulatory device for detecting and differentiating epileptic and psychogenic non-epileptic seizures

Naganur, Vaidehi D.; Kusmakar, Shitanshu; Chen, Zhibin; Palaniswami, Marimuthu S.; Kwan, Patrick; O'Brien, Terence J.

(2019), Epilepsia Open, 4(2), 309-317

DOI: 10.1002/epi4.12327

Uveitis in Patients with Multiple Sclerosis in Clinical Trials of Fingolimod

Lim, Lyndell L.; Silva, Diego G.; Lo, Tiffany C.; Pimentel, Ronald S.; Butzkueven, Helmut; Hall, Anthony J.

(2019), OPHTHALMOLOGY, 126(3), 438-444

DOI: 10.1016/j.ophtha.2018.10.013

Harmonization of pipeline for preclinical multicenter plasma protein and miRNA biomarker discovery in a rat model of post-traumatic epileptogenesis

Kamnaksh, Alaa; Puhakka, Noora; Ali, Idrish; Smith, Gregory; Aniceto, Roxanne; McCullough, Jesse; Das Gupta, Shalini; Ndode-Ekane, Xavier Ekolle; Brady, Rhys; Casillas-Espinosa, Pablo; Hudson, Matt; Santana-Gomez, Cesar; Immonen, Riikka; Abreu, Pedro Andrade de; Jones, Nigel; Shultz, Sandy; Staba, Richard J.; O'Brien, Terence J.; Agoston, Denes; Pitkänen, Asla

(2019), EPILEPSY RES, (149), 92-101

DOI: 10.1016/j.eplepsyres.2018.11.009

The selective TrkA agonist, gambogic amide, promotes osteoblastic differentiation and improves fracture healing in mice

Johnstone, Maddison R.; Brady, Rhys D.; Schuijers, Johannes A.; Church, Jarrod E.; Orr, David; Quinn, Julian M.W.; McDonald, Stuart J.; Grills, Brian L.

(2019), J MUSCULOSKEL NEURON, 19(1), 94-103

Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis

Immonen, Riikka; Smith, Gregory; Brady, Rhys D.; Wright, David; Johnston, Leigh; Harris, Neil G.; Manninen, Eppu; Salo, Raimo; Branch, Craig; Duncan, Dominique; Cabeen, Ryan; Ndode-Ekane, Xavier Ekolle; Gomez, Cesar Santana; Casillas-Espinosa, Pablo M.; Ali, Idrish; Shultz, Sandy R.; Andrade, Pedro; Puhakka, Noora; Staba, Richard J.; O'Brien, Terence J.; Toga, Arthur W.; Pitkänen, Asla; Gröhn, Olli

(2019), EPILEPSY RES, (150), 46-57

DOI: 10.1016/j.eplepsyres.2019.01.001

Multicenter study demonstrates radiomic features derived from magnetic resonance perfusion images identify pseudoprogression in glioblastoma

Elshafeey, Nabil; Kotrotsou, Aikaterini; Hassan, Ahmed; Elshafei, Nancy; Hassan, Islam; Ahmed, Sara; Abrol, Srishti; Agarwal, Anand; El Salek, Kamel; Bergamaschi, Samuel; Acharya, Jay; Moron, Fanny E.; Law, Meng; Fuller, Gregory N.; Huse, Jason T.; Zinn, Pascal O.; Colen, Rivka R.

(2019), NAT COMMUN, 10(1), 3170

DOI: 10.1038/s41467-019-11007-0

Informatics tools to assess the success of procedural harmonization in preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis

Ciszek, Robert; Ndode-Ekane, Xavier Ekolle; Gomez, Cesar Santana; Casillas-Espinosa, Pablo M.; Ali, Idrish; Smith, Gregory; Puhakka, Noora; Lapinlampi, Niina; Andrade, Pedro; Kamnaksh, Alaa; Immonen, Riikka; Paananen, Tomi; Hudson, Matthew R.; Brady, Rhys D.; Shultz, Sandy R.; O'Brien, Terence J.; Staba, Richard J.; Tohka, Jussi; Pitkänen, Asla

(2019), EPILEPSY RES, (150), 17-26

DOI: 10.1016/j.eplepsyres.2018.12.010

Selective serotonin reuptake inhibitors and risk of epilepsy after traumatic brain injury – A population based cohort study

Christensen, Jakob; Pedersen, Henrik Schou; Fenger-Grøn, Morten; Fann, Jesse R.; Jones, Nigel C.; Vestergaard, Mogens

(2019), PLOS ONE, 14(7), e0219137

DOI: 10.1371/journal.pone.0219137

Harmonization of the pipeline for seizure detection to phenotype post-traumatic epilepsy in a preclinical multicenter study on post-traumatic epileptogenesis

Casillas-Espinosa, Pablo M.; Andrade, Pedro; Santana-Gomez, Cesar; Paananen, Tomi; Smith, Gregory; Ali, Idrish; Ciszek, Robert; Ndode-Ekane, Xavier Ekolle; Brady, Rhys D.; Tohka, Jussi; Hudson, Matthew R.; Perucca, Piero; Braine, Emma L.; Immonen, Riikka; Puhakka, Noora; Shultz, Sandy R.; Jones, Nigel C.; Staba, Richard J.; Pitkänen, Asla; O'Brien, Terence J.

(2019), EPILEPSY RES, 156, 106131

DOI: 10.1016/j.eplepsyres.2019.04.011

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