Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals.

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Analysis of infection loads in Mycoplasma genitalium clinical specimens by use of a commercial diagnostic test

Murray, Gerald L.; Danielewski, Jennifer; Bodiyabadu, Kaveesha; Machalek, Dorothy A.; Bradshaw, Catriona S.; Costa, Anna Maria; Birnie, Josh; Garland, Suzanne M.

(2019), J CLIN MICROBIOL, 57(9), e00344-19.

DOI: 10.1128/JCM.00344-19

MAIT cells upregulate α4β7 in response to acute simian immunodeficiency Virus/Simian HIV infection but are resistant to peripheral depletion in pigtail macaques

Juno, Jennifer A.; Wragg, Kathleen M.; Amarasena, Thakshila; Meehan, Bronwyn S.; Mak, Jeffrey Y.W.; Liu, Ligong; Fairlie, David P.; McCluskey, James; Eckle, Sidonia B.G.; Kent, Stephen J.

(2019), J IMMUNOL, 202(7), 2105-2120.

DOI: 10.4049/jimmunol.1801405

Influenza Virus Infection Enhances Antibody-Mediated NK Cell Functions via Type I Interferon-Dependent Pathways

Jegaskanda, Sinthujan; Vanderven, Hillary A.; Tan, Hyon Xhi; Alcantara, Sheilajen; Wragg, Kathleen M.; Parsons, Matthew S.; Chung, Amy W.; Juno, Jennifer A.; Kent, Stephen J.

(2019), J VIROL, 93(5), e02090-18.

DOI: 10.1128/JVI.02090-18

A population-based analysis of invasive fungal disease in haematology-oncology patients using data linkage of state-wide registries and administrative databases

Valentine, Jake C.; Morrissey, C. Orla; Tacey, Mark A.; Liew, Danny; Patil, Sushrut; Peleg, Anton Y.; Ananda-Rajah, Michelle R.

(2019), BMC INFECT DIS, 19(1), 274

DOI: 10.1186/s12879-019-3901-y

Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198

Hawkey, Jane; Le Hello, Simon; Doublet, Benoît; Granier, Sophie A.; Hendriksen, Rene S.; Florian Fricke, W.; Ceyssens, Pieter Jan; Gomart, Camille; Billman-Jacobe, Helen; Holt, Kathryn E.; Weill, François Xavier

(2019), MICROBIOL GENOMICS, 5(7), 269

DOI: 10.1099/mgen.0.000269

Escherichia coli harboring mcr-1 in a cluster of liver transplant recipients

Macesic, Nenad; Khan, Sabrina; Giddins, Marla J.; Freedberg, Daniel E.; Whittier, Susan; Green, Daniel A.; Furuya, E. Yoko; Verna, Elizabeth C.; Annavajhala, Medini K.; Gomez-Simmonds, Angela; Uhlemann, Anne Catrin

(2019), ANTIMICROB AGENTS CH, 63(6), e02680-18.

DOI: 10.1128/AAC.02680-18

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

Rees, Vanessa E.; Deveson Lucas, Deanna S.; López-Causapé, Carla; Huang, Yuling; Kotsimbos, Tom; Bulitta, Jürgen B.; Rees, Murray C.; Barugahare, Adele; Peleg, Anton Y.; Nation, Roger L.; Oliver, Antonio; Boyce, John D.; Landersdorfer, Cornelia B.

(2019), ANTIMICROB AGENTS CH, 63(4), e02538-18.

DOI: 10.1128/AAC.02538-18

Improving immunological insights into the ferret model of human viral infectious disease

Wong, Julius; Layton, Daniel; Wheatley, Adam K.; Kent, Stephen J.

(2019), INFLUENZA OTHER RESP, 13(6), 535-546.

DOI: 10.1111/irv.12687

Perturbation of mucosal-associated invariant T cells and iNKT cells in HIV infection

Juno, Jennifer A.; Phetsouphanh, Chansavath; Klenerman, Paul; Kent, Stephen J.

(2019), CURR OPIN HIV AIDS, 14(2), 77-84.

DOI: 10.1097/COH.0000000000000526

Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae

Wyres, Kelly L.; Wick, Ryan R.; Judd, Louise M.; Froumine, Roni; Tokolyi, Alex; Gorrie, Claire L.; Lam, Margaret M.C.; Duchêne, Sebastián; Jenney, Adam; Holt, Kathryn E.

(2019), PLOS GENET, 15(4), e1008114.

DOI: 10.1371/journal.pgen.1008114

Performance of neural network basecalling tools for Oxford Nanopore sequencing

Wick, Ryan R.; Judd, Louise M.; Holt, Kathryn E.

(2019), GENOME BIOL, 20(1), 129

DOI: 10.1186/s13059-019-1727-y

Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals

Feng, Yen Chen Anne; Howrigan, Daniel P.; Abbott, Liam E.; Tashman, Katherine; Cerrato, Felecia; Singh, Tarjinder; Heyne, Henrike; Byrnes, Andrea; Churchhouse, Claire; Watts, Nick; Solomonson, Matthew; Lal, Dennis; Heinzen, Erin L.; Dhindsa, Ryan S.; Stanley, Kate E.; Cavalleri, Gianpiero L.; Hakonarson, H.; Helbig, Ingo; Krause, Roland; May, Patrick; Weckhuysen, S.; Petrovski, Slavé; Kamalakaran, Sitharthan; Sisodiya, Sanjay M.; Cossette, Patrick; Cotsapas, C.; De Jonghe, P.; Dixon-Salazar, T.; Guerrini, R.; Kwan, Patrick; Marson, Anthony G.; Stewart, R.; Depondt, Chantal; Dlugos, Dennis J.; Scheffer, Ingrid E.; Striano, Pasquale; Freyer, Catharine; McKenna, K.; Regan, Brigid M.; Bellows, Susannah T.; Leu, Costin; Bennett, Caitlin A.; Johns, Esther M.C.; Macdonald, Alexandra; Shilling, Hannah; Burgess, Rosemary; Weckhuysen, Dorien; Bahlo, Melanie; O'Brien, Terence J.; Todaro, Marian; Stamberger, Hannah; Andrade, Danielle M.; Sadoway, Tara R.; Mo, K.; Krestel, H.; Gallati, Sabina; Papacostas, Savvas S.; Kousiappa, Ioanna; Tanteles, George A.; Štěrbová, Katalin; Vlčková, Markéta; Sedláčková, L.; Laššuthová, P.; Klein, Karl Martin; Rosenow, F.; Reif, Philipp S.; Knake, Susanne; Kunz, Wolfram S.; Zsurka, Gábor; Elger, Christian E.; Bauer, Jürgen; Rademacher, Michael; Pendziwiat, Manuela; Muhle, Hiltrud; Rademacher, Annika; van Baalen, Andreas; von Spiczak, S.; Stephani, Ulrich; Afawi, Zaid; Korczyn, Amos D.; Kanaan, M.; Canavati, Christina; Kurlemann, Gerhard; Müller-Schlüter, K.; Kluger, Gerhard; Häusler, Martin; Blatt, Ilan; Lemke, Johannes R.; Krey, I.; Weber, Yvonne G.; Wolking, Stefan; Becker, Felicitas; Hengsbach, Christian; Rau, S.; Maisch, A. F.; Steinhoff, Bernhard J.; Schulze-Bonhage, Andreas; Schubert-Bast, Susanne; Schreiber, Herbert; Borggräfe, Ingo; Schankin, Christoph J.; Mayer, Thomas; Korinthenberg, Rudolf; Brockmann, Knut; Dennig, Dieter; Madeleyn, Rene; Kälviäinen, Reetta; Auvinen, Pia; Saarela, Anni; Linnankivi, T.; Lehesjoki, Anna Elina; Rees, Mark I.; Chung, Seo Kyung; Pickrell, William O.; Powell, Robert; Schneider, Natascha; Balestrini, Simona; Zagaglia, Sara; Braatz, Vera; Johnson, Michael R.; Auce, P.; Sills, Graeme J.; Baum, Larry W.; Sham, P. C.; Cherny, Stacey S.; Lui, Colin H.T.; Barišić, Nina; Delanty, Norman; Doherty, Colin P.; Shukralla, Arif; McCormack, Mark; El-Naggar, Hany; Canafoglia, L.; Franceschetti, Silvana; Castellotti, Barbara; Granata, Tiziana; Zara, Federico; Iacomino, Michele; Madia, Francesca; Vari, Maria Stella; Mancardi, Maria Margherita; Salpietro, Vincenzo; Bisulli, Francesca; Tinuper, P.; Licchetta, L.; Pippucci, Tommaso; Stipa, Carlotta; Minardi, Raffaella; Gambardella, Antonio; Labate, Angelo; Annesi, Grazia; Manna, Lorella; Gagliardi, Monica; Parrini, E.; Mei, Davide; Vetro, Annalisa; Bianchini, Claudia; Montomoli, Martino; Doccini, V.; Marini, C.; Suzuki, Toshimitsu; Inoue, Y.; Yamakawa, Kazuhiro; Tumiene, Birute; Sadleir, Lynette G.; King, Chontelle; Mountier, E.; Caglayan, S. Hande; Arslan, Mutluay; Yapıcı, Z.; Yis, Uluc; Topaloglu, Pınar; Kara, Bulent; Turkdogan, Dilsad; Gundogdu-Eken, Aslı; Bebek, Nerses; Uğur-İşeri, S.; Baykan, Betül; Salman, Barış; Haryanyan, G.; Yücesan, E.; Kesim, Yeşim; Özkara, Çiğdem; Poduri, Annapurna; Shiedley, Beth R.; Shain, Catherine; Buono, Russell J.; Ferraro, Thomas N.; Sperling, Michael R.; Lo, Warren; Privitera, Michael; French, Jacqueline A.; Schachter, Steven; Kuzniecky, Ruben I.; Devinsky, O.; Hegde, Manu; Khankhanian, P.; Helbig, Katherine L.; Ellis, Colin A.; Spalletta, Gianfranco; Piras, Fabrizio; Piras, Federica; Gili, Tommaso; Ciullo, Valentina; Reif, Andreas; McQuillin, Andrew; Bass, Nick; McIntosh, Andrew; Blackwood, Douglas; Johnstone, M.; Palotie, A.; Pato, Michele T.; Pato, Carlos N.; Bromet, Evelyn J.; Carvalho, Celia Barreto; Achtyes, Eric D.; Azevedo, Maria Helena; Kotov, R.; Lehrer, Douglas S.; Malaspina, Dolores; Marder, Stephen R.; Medeiros, Helena; Morley, Christopher P.; et al.

(2019), AM J HUM GENET, 105(2), 267-282

DOI: 10.1016/j.ajhg.2019.05.020

Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors

Ilsley, Melissa D.; Huang, Stephen; Magor, Graham W.; Landsberg, Michael J.; Gillinder, Kevin R.; Perkins, Andrew C.

(2019), BMC GENOMICS, 20(1), 417

DOI: 10.1186/s12864-019-5805-z

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, Ilaria; Wen, Ji; Meggendorfer, Manja; Choi, John K.; Shi, Lei; Pounds, Stanley B.; Carmichael, Catherine L.; Masih, Katherine E.; Morris, Sarah M.; Lindsley, R. Coleman; Janke, Laura J.; Alexander, Thomas B.; Song, Guangchun; Qu, Chunxu; Li, Yongjin; Payne-Turner, Debbie; Tomizawa, Daisuke; Kiyokawa, Nobutaka; Valentine, Marcus; Valentine, Virginia; Basso, Giuseppe; Locatelli, Franco; Enemark, Eric J.; Kham, Shirley K.Y.; Yeoh, Allen E.J.; Ma, Xiaotu; Zhou, Xin; Sioson, Edgar; Rusch, Michael; Ries, Rhonda E.; Stieglitz, Elliot; Hunger, Stephen P.; Wei, Andrew H.; To, L. Bik; Lewis, Ian D.; D’Andrea, Richard J.; Kile, Benjamin T.; Brown, Anna L.; Scott, Hamish S.; Hahn, Christopher N.; Marlton, Paula; Pei, Deqing; Cheng, Cheng; Loh, Mignon L.; Ebert, Benjamin L.; Meshinchi, Soheil; Haferlach, Torsten; Mullighan, Charles G.

(2019), NAT GENET, 51(4), 694-704.

DOI: 10.1038/s41588-019-0375-1

Meta-analysis of Grainyhead-like dependent transcriptional networks

Mathiyalagan, Nishanthi; Miles, Lee B.; Anderson, Peter J.; Wilanowski, Tomasz; Grills, Brian L.; McDonald, Stuart J.; Keightley, M. Cristina; Charzynska, Agata; Dabrowski, Michal; Dworkin, Sebastian

(2019), GENES-BASEL, 10(11, 876

DOI: 10.3390/genes10110876

Statistical modelling outcome of in vitro fertilization and intracytoplasmic sperm injection

Xu, Boyun; Liu, Chang; Qian, Lianfen; Qu, Yue; Su, Weijue; Xu, Jialing; Zhao, Junzhao

(2019), COMB CHEM HIGH T SCR, 22(4), 225-231.

DOI: 10.2174/1386207322666190404145448

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

Liu, You Dong; Yu, Liang; Ying, Le; Balic, Jesse; Gao, Hugh; Deng, Nian Tao; West, Alison; Yan, Feng; Ji, Cheng Bo; Gough, Daniel; Tan, Patrick; Jenkins, Brendan J.; Li, Ji Kun

(2019), INT J CANCER, 144(12), 3056-3069.

DOI: 10.1002/ijc.32060

Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1

Deuss, Felix A; Watson, Gabrielle M; Goodall, Katharine J; Leece, Isobel; Chatterjee, Sayantani; Fu, Zhihui; Thaysen-Andersen, Morten; Andrews, Daniel M; Rossjohn, Jamie; Berry, Richard

(2019), J BIOL CHEM, 294(33), 12534-12546.

DOI: 10.1074/jbc.RA119.009261

Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice

Daglas, Maria; Draxler, Dominik F.; Ho, Heidi; McCutcheon, Fiona; Galle, Adam; Au, Amanda E.; Larsson, Pia; Gregory, Julia; Alderuccio, Frank; Sashindranath, Maithili; Medcalf, Robert L.

(2019), CELL REP, 29(5), 1178-1191.e6.

DOI: 10.1016/j.celrep.2019.09.046

Ligand-Functionalized Poly(ethylene glycol) Particles for Tumor Targeting and Intracellular Uptake

Cui, Jiwei; Alt, Karen; Ju, Yi; Gunawan, Sylvia T.; Braunger, Julia A.; Wang, Ting Yi; Dai, Yunlu; Dai, Qiong; Richardson, Joseph J.; Guo, Junling; Björnmalm, Mattias; Hagemeyer, Christoph E.; Caruso, Frank

(2019), BIOMACROMOLECULES, 20(9), 3592-3600.

DOI: 10.1021/acs.biomac.9b00925

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