Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Platelets are not just for clots

McFadyen JD, Kaplan ZS

(2015), Transfus Med Rev, 29(2), 110-9

Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression

Martin A, Salvador F, Moreno-Bueno G, Floristán A, Ruiz-Herguido C, Cuevas EP, Morales S, Santos V, Csiszar K, Dubus P, Haigh JJ, Bigas A, Portillo F, Cano A

(2015), EMBO J, 34(8), 1090-109

14-3-3ζ coordinates adipogenesis of visceral fat

Lim GE, Albrecht T, Piske M, Sarai K, Lee JT, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD

(2015), Nat Commun, 6, 7671

NOX2 is critical for heterotypic neutrophil-platelet interactions during vascular inflammation

Kim K, Li J, Tseng A, Andrews RK, Cho J

(2015), Blood, 126(16), 1952-64

Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4

Kaplan ZS, Zarpellon A, Alwis I, Yuan Y, McFadyen J, Ghasemzadeh M, Schoenwaelder SM, Ruggeri ZM, Jackson SP

(2015), Nat Commun, 6, 7835

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

Horvay K, Jardé T, Casagranda F, Perreau VM, Haigh K, Nefzger CM, Akhtar R, Gridley T, Berx G, Haigh JJ, Barker N, Polo JM, Hime GR, Abud HE

(2015), EMBO J, 34(10), 1319-35

The dynamics of adult haematopoiesis in the bone and bone marrow environment

Ho MS, Medcalf RL, Livesey SA, Traianedes K

(2015), Br J Haematol, 170(4), 472-86

Particle generation, functionalization and sortase A-mediated modification with targeting of single-chain antibodies for diagnostic and therapeutic use

Hagemeyer CE, Alt K, Johnston AP, Such GK, Ta HT, Leung MK, Prabhu S, Wang X, Caruso F, Peter K

(2015), Nat Protoc, 10(1), 90-105

Nanoporous metal-phenolic particles as ultrasound imaging probes for hydrogen peroxide

Guo J, Wang X, Henstridge DC, Richardson JJ, Cui J, Sharma A, Febbraio MA, Peter K, de Haan JB, Hagemeyer CE, Caruso F

(2015), Adv Healthc Mater, 4(14), 2170-5

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling

Goossens S, Radaelli E, Blanchet O, Durinck K, Van der Meulen J, Peirs S, Taghon T, Tremblay CS, Costa M, Farhang Ghahremani M, De Medts J, Bartunkova S, Haigh K, Schwab C, Farla N, Pieters T, Matthijssens F, Van Roy N, Best JA, Deswarte K, Bogaert P, Carmichael C, Rickard A, Suryani S, Bracken LS, Alserihi R, Canté-Barrett K, Haenebalcke L, Clappier E, Rondou P, Slowicka K, Huylebroeck D, Goldrath AW, Janzen V, McCormack MP, Lock RB, Curtis DJ, Harrison C, Berx G, Speleman F, Meijerink JP, Soulier J, Van Vlierberghe P, Haigh JJ

(2015), Nat Commun, 6, 5794

Intravascular leukocyte migration through platelet thrombi: directing leukocytes to sites of vascular injury

Ghasemzadeh M, Hosseini E

(2015), Thromb Haemost, 113(6), 1224-35

Phosphorothioate backbone modifications of nucleotide-based drugs are potent platelet activators

Flierl U, Nero TL, Lim B, Arthur JF, Yao Y, Jung SM, Gitz E, Pollitt AY, Zaldivia MT, Jandrot-Perrus M, Schäfer A, Nieswandt B, Andrews RK, Parker MW, Gardiner EE, Peter K

(2015), J Exp Med, 212(2), 129-37

Novel biological insights in T-cell acute lymphoblastic leukemia

Durinck K, Goossens S, Peirs S, Wallaert A, Van Loocke W, Matthijssens F, Pieters T, Milani G, Lammens T, Rondou P, Van Roy N, De Moerloose B, Benoit Y, Haigh J, Speleman F, Poppe B, Van Vlierberghe P

(2015), Exp Hematol, 43(8), 625-39

The fibrinolytic system-more than fibrinolysis?

Draxler DF, Medcalf RL

(2015), Transfus Med Rev, 29(2), 102-9

Disseminated enteroviral infection associated with obinutuzumab

Dendle C, Gilbertson M, Korman TM, Golder V, Morand E, Opat S

(2015), Emerg Infect Dis, 21(9), 1661-3

Immunohistological description of nongestational ovarian choriocarcinoma in two female mice with conditional loss of Trp53 driven by the Tie2 promoter

Castiglioni V, Farhang Ghahremani M, Goossens S, De Maglie M, Ardizzone M, Haigh JJ, Radaelli E

(2015), Vet Pathol, 52(4), 752-6

Thrombin-induced reactive oxygen species generation in platelets: a novel role for protease-activated receptor 4 and GPIbα

Carrim N, Arthur JF, Hamilton JR, Gardiner EE, Andrews RK, Moran N, Berndt MC, Metharom P

(2015), Redox Biol, 6, 640-7

Comparison of intermittent and continuous extracorporeal treatments for the enhanced elimination of dabigatran

Bouchard J, Ghannoum M, Bernier-Jean A, Williamson D, Kershaw G, Weatherburn C, Eris JM, Tran H, Patel JP, Roberts DM

(2015), Clin Toxicol, 53(3), 156-63

Dendritic cell-mediated phagocytosis but not immune activation is enhanced by plasmin

Borg RJ, Samson AL, Au AE, Scholzen A, Fuchsberger M, Kong YY, Freeman R, Mifsud NA, Plebanski M, Medcalf RL

(2015), PLoS One, 10(7), e0131216

Strategies to rescue the consequences of inducible arginase-1 deficiency in mice

Ballantyne LL, Sin YY, St Amand T, Si J, Goossens S, Haenebalcke L, Haigh JJ, Kyriakopoulou L, Schulze A, Funk CD

(2015), PLoS One, 10(5), e0125967

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