Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Clopidogrel Resistance: case reports of CYP2C19 gene variants in suspected coronary stent thrombosis

Dick RJ, Dear AE, Byron KA

(2011), Heart Lung Circ, 20(10), 657-8

The catalytic class I(A) PI3K isoforms play divergent roles in breast cancer cell migration

De Laurentiis A, Pardo OE, Palamidessi A, Jackson SP, Schoenwaelder SM, Reichmann E, Scita G, Arcaro A

(2011), Cell Signal, 23(3), 529-41

Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis

Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM

(2011), Cancer Cell, 20(5), 635-48

High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction

Cranmer SL, Ashworth KJ, Yao Y, Berndt MC, Ruggeri ZM, Andrews RK, Jackson SP

(2011), Blood, 117(9), 2718-27

Critical role of cRel subunit of NF-ΚB in sepsis survival

Courtine E, Pène F, Cagnard N, Toubiana J, Fitting C, Brocheton J, Rousseau C, Gerondakis S, Chiche JD, Ouaaz F, Mira JP

(2011), Infect Immun, 79(5), 1848-54

The NF-ΚB transcription factor c-Rel is required for Th17 effector cell development in experimental autoimmune encephalomyelitis

Chen G, Hardy K, Pagler E, Ma L, Lee S, Gerondakis S, Daley S, Shannon MF

(2011), J Immunol, 187(9), 4483-91

The unique and cooperative roles of the Grainy head-like transcription factors in epidermal development reflect unexpected target gene specificity

Boglev Y, Wilanowski T, Caddy J, Parekh V, Auden A, Darido C, Hislop NR, Cangkrama M, Ting SB, Jane SM

(2011), Dev Biol, 349(2), 512-22

TNF receptor-associated factor 4 (TRAF4) is a novel binding partner of glycoprotein Ib and glycoprotein VI in human platelets

Arthur JF, Shen Y, Gardiner EE, Coleman L, Murphy D, Kenny D, Andrews RK, Berndt MC

(2011), J Thromb Haemost, 9(1), 163-72

Soluble glycoprotein VI is raised in the plasma of patients with acute ischemic stroke

Al-Tamimi M, Gardiner EE, Thom JY, Shen Y, Cooper MN, Hankey GJ, Berndt MC, Baker RI, Andrews RK

(2011), Stroke, 42(2), 498-500

A GPIb-IX-V complex signaling environment

Gardiner EE

(2010), J Thromb Haemost, 8(5), 1075-6

Early hippocampal oxidative stress is a direct consequence of seizures in the rapid electrical amygdala kindling model

Sashindranath M, McLean KJ, Trounce IA, Cotton RG, Cook MJ

(2010), Epilepsy Res, 90(3), 285-94

The thienopyridine class of antiplatelet drugs

Kaplan Z, Al-Daher S, Salem H

(2010), Med Today, 11(8), LF to check in library

PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading

Zeller KS, Idevall-Hagren O, Stefansson A, Velling T, Jackson SP, Downward J, Tengholm A, Johansson S

(2010), Cell Signal, 22(12), 1838-48

Nerve growth factor inhibits metalloproteinase-disintegrins and blocks ectodomain shedding of platelet glycoprotein VI

Wijeyewickrema LC, Gardiner EE, Gladigau EL, Berndt MC, Andrews RK

(2010), J Biol Chem, 285(16), 11793-9

A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood

Tovar-Lopez FJ, Rosengarten G, Westein E, Khoshmanesh K, Jackson SP, Mitchell A, Nesbitt WS

(2010), Lab Chip, 10(3), 291-302

Transgenic, inducible RNAi in megakaryocytes and platelets in mice

Takiguchi M, James C, Josefsson EC, Carmichael CL, Premsrirut PK, Lowe SW, Hamilton JR, Huang DC, Kile BT, Dickins RA

(2010), J Thromb Haemost, 8(12), 2751-6

The plasminogen activator inhibitor 2 transcript is destabilized via a multi-component 3' UTR localized adenylate and uridylate-rich instability element in an analogous manner to cytokines and oncogenes

Stasinopoulos S, Mariasegaram M, Gafforini C, Nagamine Y, Medcalf RL

(2010), FEBS J, 277(5), 1331-44

No longer the poor relations

Spencer A

(2010), Blood, 116(19), 3685-6

Phosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces

Schoenwaelder SM, Ono A, Nesbitt WS, Lim J, Jarman K, Jackson SP

(2010), J Biol Chem, 285(4), 2886-96

Generation and characterization of mice with null mutation of the chloride intracellular channel 1 gene

Qiu MR, Jiang L, Matthaei KI, Schoenwaelder SM, Kuffner T, Mangin P, Joseph JE, Low J, Connor D, Valenzuela SM, Curmi PM, Brown LJ, Mahaut-Smith M, Jackson SP, Breit SN

(2010), Genesis, 48(2), 127-36

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