Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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β-amyloid in biological samples: not all Aβ detection methods are created equal

Adlard PA, Li QX, McLean C, Masters CL, Bush AI, Fodero-Tavoletti M, Villemagne V, Barnham KJ

(2014), Front Aging Neurosci, 6, 203

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, Eriksson M, Klevebring D,

(2014), Nat Commun, 4, 4999

MicroRNA related polymorphisms and breast cancer risk

Khan S, Greco D, Michailidou K, Milne RL, Muranen TA, Heikkinen T, Aaltonen K, Dennis J, Bolla MK, Liu J, Hall P, Irwanto A, Humphreys K, Li J, Czene K, Chang-Claude J, Hein R, Rudolph A, Seibold P, Flesch-Janys D, Fletcher O, Peto J, dos Santos Silva I,

(2014), PLoS One, 9(11), e109973

Epigenome-wide methylation in DNA from peripheral blood as a marker of risk for breast cancer

Severi G, Southey MC, English DR, Jung CH, Lonie A, McLean C, Tsimiklis H, Hopper JL, Giles GG, Baglietto L

(2014), Breast Cancer Res Treat, 148(3), 665-73

Mutations in RAB39B cause X-linked intellectual disability and early-onset Parkinson disease with α-synuclein pathology

Wilson GR, Sim JC, McLean C, Giannandrea M, Galea CA, Riseley JR, Stephenson SE, Fitzpatrick E, Haas SA, Pope K, Hogan KJ, Gregg RG, Bromhead CJ, Wargowski DS, Lawrence CH, James PA, Churchyard A, Gao Y, Phelan DG, Gillies G, Salce N, Stanford L, Marsh AP

(2014), Am J Hum Genet, 95(6), 729-35

A 67-year-old man with painful diplopia: question

Fok A, McLean CA, Chandra RV, Seneviratne U

(2014), J Clin Neurosci, 21(12), 2227, 2260

Creutzfeldt-Jakob disease surveillance in Australia, update to December 2013

Klug GM, Boyd A, Sarros S, Stehmann C, Simpson M, McLean CA, Masters CL, Collins SJ

(2014), Commun Dis Intell Q Rep, 38(4), E348-55

Preoperative sepsis and postoperative thrombosis

Myles PS

(2014), Br Med J, 349, g5444

Generalizability of anaesthesia study populations

Myles PS

(2014), Br J Anaesth, 113(4), 535-6

Untangling the triple low: causal inference in anesthesia research

Myles PS

(2014), Anesthesiology, 121(1), 1-3

Antifibrinolytics, aspirin and cardiac surgery: evidence, guidelines and implications for current research

Myles PS

(2014), Anaesth Intensive Care, 42(3), 293-7

Meaningful outcome measures in cardiac surgery

Myles PS

(2014), J Extra Corpor Technol, 46(1), 23-7

Ethical and scientific considerations for patient enrollment into concurrent clinical trials

Myles PS, Williamson E, Oakley J, Forbes A

(2014), Trials, 15, 470

A cohort and database study of airway management in patients undergoing thyroidectomy for retrosternal goitre

Gilfillan N, Ball CM, Myles PS, Serpell J, Johnson WR, Paul E

(2014), Anaesth Intensive Care, 42(6), 700-8

Perioperative aspirin and clonidine and risk of acute kidney injury: a randomized clinical trial

Garg AX, Kurz A, Sessler DI, Cuerden M, Robinson A, Mrkobrada M, Parikh CR, Mizera R, Jones PM, Tiboni M, Font A, Cegarra V, Gomez MF, Meyhoff CS, VanHelder T, Chan MT, Torres D, Parlow J, Clanchet Mde N, Amir M, Bidgoli SJ, Pasin L, Martinsen K, Malaga G

(2014), JAMA, 312(21), 2254-64

Evaluation of differences in patient and physician perception of benefit and risks of aspirin and antifibrinolytic therapy in cardiac surgery

Myles PS, Thompson G, Fedorow C, Farrington C, Sheridan N

(2014), Anaesth Intensive Care, 42(5), 592-8

The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial

Myles PS, Leslie K, Chan MT, Forbes A, Peyton PJ, Paech MJ, Beattie WS, Sessler DI, Devereaux PJ, Silbert B, Schricker T, Wallace S; ANZCA Trials Group for the ENIGMA-II investigators

(2014), Lancet, 384(9952), 1446-54

Aspirin and clonidine in non-cardiac surgery: acute kidney injury substudy protocol of the Perioperative Ischaemic Evaluation (POISE) 2 randomised controlled trial

Garg AX, Kurz A, Sessler DI, Cuerden M, Robinson A, Mrkobrada M, Parikh C, Mizera R, Jones PM, Tiboni M, Rodriguez RG, Popova E, Rojas Gomez MF, Meyhoff CS, Vanhelder T, Chan MT, Torres D, Parlow J, de Nadal Clanchet M, Amir M, Bidgoli SJ, Pasin L, Martin

(2014), BMJ Open, 4(2), e004886

A pilot study for a prospective, randomized, double-blind trial of the influence of anesthetic depth on long-term outcome

Short TG, Leslie K, Campbell D, Chan MT, Corcoran T, O'Loughlin E, Frampton C, Myles P

(2014), Anesth Analg, 118(5), 981-6

Does anaesthesia with nitrous oxide affect mortality or cardiovascular morbidity? A systematic review with meta-analysis and trial sequential analysis

Imberger G, Orr A, Thorlund K, Wetterslev J, Myles P, MØller AM

(2014), Br J Anaesth, 112(3), 410-26