Burns research

Clinical research focuses on the management and outcomes of patients with Toxic Epidermal Necrolysis (TENS); the effect of gender on mortality in burn patients; and fluid management and blood transfusion practices.

The Victorian Adult Burns Service at The Alfred provides the statewide service for adult patients with severe burn injuries.

Clinical research topics in 2015 have included gender differences in cytokine response to burn injury, troponin levels in patients with burns and the early microbiological profile of the burn wound.

A prospective trial is under way to test the validity of a predictive equation for dressing requirements, which will contribute to state disaster response preparation and planning. Laboratory research is focused on techniques for keratinocyte culture and tissue engineering for skin substitutes.

Postgraduate students

  • 3 PhD students
  • 3 Masters students

Publications

Wound healing and dermal regeneration in severe burn patients treated with NovoSorb® Biodegradable Temporising Matrix: A prospective clinical study

Lo CH, Brown JN, Dantzer EJG, Maitz PKM, Vandervord JG, Wagstaff MJD, Barker TM, Cleland H

(2022), Burns, 48(3), 529-38

DOI: 10.1016/j.burns.2021.07.014

erformance of BEAMS Risk of Death Score for Mortality Prediction in Australian and New Zealand Burns Patients

Lu P, Burrell A, Bailey M, Moore E, Pilcher D, Cleland H

(2022), J Burn Care Res, 43(6), 1434-9

DOI: 10.1093/jbcr/irac053

Biomarkers for the Early Diagnosis of Sepsis in Burns: Systematic Review and Meta-analysis

Li AT, Moussa A, Gus E, Paul E, Yii E, Romero L, Lin ZC, Padiglione A, Lo CH, Cleland H, Cheng AC

(2022), Ann Surg, 275(4), 654-62

DOI: 10.1097/SLA.0000000000005198

View all publications for Burns research