Skin Tissue Culture Laboratory
The work of the Skin Tissue Culture Laboratory in evaluating the role of dermal templates in physiologic wound closure as a scaffold for tissue repair has demonstrated significant differences between different scaffolds.
Differences in inflammatory response and vascularisation rates in a mouse model require further investigation to relate early responses to take rates, and longer term scarring outcomes.
This work informs a clinical trial, expected to commence in 2015, evaluating a novel synthetic dermal substitute. A clinical trial using cultured epithelial autografts produced in our laboratory is currently under way, and will provide further information of the role of dermis in the healing of burn injury.