Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Effect of a resuscitation quality improvement programme on outcomes from out-of-hospital cardiac arrest

Nehme, Ziad; Ball, Jocasta; Stephenson, Michael; Walker, Tony; Stub, Dion; Smith, Karen

(2021), RESUSCITATION, 162, 236-244

DOI: 10.1016/j.resuscitation.2021.03.007

Attenuating PI3K/Akt- mTOR pathway reduces dihydrosphingosine 1 phosphate mediated collagen synthesis and hypertrophy in primary cardiac cells

Magaye, Ruth R.; Savira, Feby; Hua, Yue; Xiong, Xin; Huang, Li; Reid, Christopher; Flynn, Bernard L.; Kaye, David; Liew, Danny; Wang, Bing H.

(2021), INT J BIOCHEM CELL B, 134, 105952

DOI: 10.1016/j.biocel.2021.105952

Effects of lignocaine vs. opioids on antiplatelet activity of ticagrelor

Fernando, Himawan; Duong, Thy; Huynh, Kevin; Noonan, Jonathan; Shaw, James; Duffy, Stephen J.; Nehme, Ziad; Smith, Karen; Myles, Paul S.; Meikle, Peter J.; Peter, Karlheinz; Stub, Dion

(2021), EUR HEART J, 42(39), 4025-4036

DOI: 10.1093/eurheartj/ehab557

Outcomes of Percutaneous Coronary Intervention in Patients With Rheumatoid Arthritis

Dawson, Luke P.; Dinh, Diem; O'Brien, Jessica; Duffy, Stephen J.; Guymer, Emma; Brennan, Angela; Clark, David; Oqueli, Ernesto; Hiew, Chin; Freeman, Melanie; Reid, Christopher M.; Ajani, Andrew E.; ,

(2021), AM J CARDIOL, 140, 39-46

DOI: 10.1016/j.amjcard.2020.10.048

Adverse impact of chronic kidney disease on clinical outcomes following percutaneous coronary intervention

Bloom, Jason E.; Dinh, Diem T.; Noaman, Samer; Martin, Catherine; Lim, Michael; Bachelor, Riley; Zheng, Wayne; Reid, Christopher; Brennan, Angela; Lefkovits, Jeffrey; Cox, Nicholas; Duffy, Stephen J.; Chan, William

(2021), CATHETER CARDIO INTE, 97(6), E801-E809

DOI: 10.1002/ccd.29436

Impact of emergency medical service delays on time to reperfusion and mortality in STEMI

Alrawashdeh, Ahmad; Nehme, Ziad; Williams, Brett; Smith, Karen; Brennan, Angela; Dinh, Diem T.; Liew, Danny; Lefkovits, Jeffrey; Stub, Dion

(2021), Open heart, 8(1), e001654

DOI: 10.1136/openhrt-2021-001654

Colchicine in Patients With Acute Coronary Syndrome

Tong, David C.; Bloom, Jason E.; Quinn, Stephen; Nasis, Arthur; Hiew, Chin; Roberts-Thomson, Philip; Adams, Heath; Sriamareswaran, Rumes; Htun, Nay M.; Wilson, William; Stub, Dion; van Gaal, William; Howes, Laurie; Yeap, Allysha; Yip, Brian; Wu, Sam; Pere

(2021), CIRCULATION, 144(19), 1584-1586

DOI: 10.1161/CIRCULATIONAHA.121.054610

Renal ACE2 (Angiotensin-Converting Enzyme 2) Expression Is Modulated by Dietary Fiber Intake, Gut Microbiota, and Their Metabolites

Snelson, Matthew; Muralitharan, Rikeish R.; Dinakis, Evany; Nakai, Michael; Jama, Hamdi A.; Shihata, Waled A.; Johnson, Chad; Kaye, David M.; Mackay, Charles R.; Burrell, Louise M.; Coughlan, Melinda T.; Marques, Francine Z.

(2021), HYPERTENSION, 77(6), e53-e55

DOI: 10.1161/HYPERTENSIONAHA.121.17039

Microbial Interventions to Control and Reduce Blood Pressure in Australia (MICRoBIA)

Rhys-Jones, Dakota; Climie, Rachel E.; Gill, Paul A.; Jama, Hamdi A.; Head, Geoffrey A.; Gibson, Peter R.; Kaye, David M.; Muir, Jane G.; Marques, Francine Z.

(2021), TRIALS, 22(1), 496

DOI: 10.1186/s13063-021-05468-2

Gender Differences in Healthy Lifestyle Adherence Following Percutaneous Coronary Intervention for Coronary Artery Disease

Perera, Sheneli; Aslam, Anum; Stehli, Julia; Kaye, David; Layland, Jamie; Nicholls, Stephen J.; Cameron, James; Zaman, Sarah

(2021), HEART LUNG CIRC, 30(1), E37-E40

DOI: 10.1016/j.hlc.2020.06.024

Essential Hypertension Is Associated with Changes in Gut Microbial Metabolic Pathways

Nakai, Michael; Ribeiro, Rosilene V.; Stevens, Bruce R.; Gill, Paul; Muralitharan, Rikeish R.; Yiallourou, Stephanie; Muir, Jane; Carrington, Melinda; Head, Geoffrey A.; Kaye, David M.; Marques, Francine Z.

(2021), HYPERTENSION, 78(3), 804-815

DOI: 10.1161/HYPERTENSIONAHA.121.17288

Dihydrosphingosine driven enrichment of sphingolipids attenuates TGFβ induced collagen synthesis in cardiac fibroblasts

Magaye, Ruth R.; Savira, Feby; Xiong, Xin; Huynh, Kevin; Meikle, Peter J.; Reid, Christopher; Flynn, Bernard L.; Kaye, David; Liew, Danny; Wang, Bing H.

(2021), International journal of cardiology. Heart & vasculature, 35, 100837

DOI: 10.1016/j.ijcha.2021.100837

Estimating the economic impacts of percutaneous coronary intervention in Australia

Lee, Peter; Brennan, Angela L.; Stub, Dion; Dinh, Diem T.; Lefkovits, Jeffrey; Reid, Christopher M.; Zomer, Ella; Liew, Danny

(2021), BMJ OPEN, 11(12), 53305

DOI: 10.1136/bmjopen-2021-053305

Old drug, new trick: Tilorone, a Broad-Spectrum Antiviral Drug as a Potential Anti-Fibrotic Therapeutic for the Diseased Heart

Horlock, Duncan; Kaye, David M.; Winbanks, Catherine E.; Gao, Xiao Ming; Kiriazis, Helen; Donner, Daniel G.; Gregorevic, Paul; McMullen, Julie R.; Bernardo, Bianca C.

(2021), PHARMACEUTICALS-BASE, 14(3), 263

DOI: 10.3390/ph14030263

The Gut Microbiota and Their Metabolites in Human Arterial Stiffness

Dinakis, Evany; Nakai, Michael; Gill, Paul A.; Yiallourou, Stephanie; Sata, Yusuke; Muir, Jane; Carrington, Melinda; Head, Geoffrey A.; Kaye, David M.; Marques, Francine Z.

(2021), HEART LUNG CIRC, 30(11), 1716-1725

DOI: 10.1016/j.hlc.2021.07.022

The gut microbiome of heart failure with preserved ejection fraction

Beale, Anna L.; O’Donnell, Joanne A.; Nakai, Michael E.; Nanayakkara, Shane; Vizi, Donna; Carter, Kaye; Dean, Eliza; Ribeiro, Rosilene V.; Yiallourou, Stephanie; Carrington, Melinda J.; Marques, Francine Z.; Kaye, David M.

(2021), J AM HEART ASSOC, 10(13), e020654

DOI: 10.1161/JAHA.120.020654

Previous Pre-Eclampsia, Gestational Diabetes and Hypertension Place Women at High Cardiovascular Risk

Aslam, Anum; Perera, Sheneli; Watts, Monique; Kaye, David; Layland, Jaime; Nicholls, Stephen J.; Cameron, James; Zaman, Sarah

(2021), HEART LUNG CIRC, 30, 154-157

DOI: 10.1016/j.hlc.2020.06.022

Impact of a mass media campaign on presentations and ambulance use for acute coronary syndrome

Eastwood K, Howell S, Nehme Z, Finn J, Smith K, Cameron P, Stub D, Bray JE

(2021), Open Heart, 8(2), e001792

DOI: 10.1136/openhrt-2021-001792

Association between pre-hospital chest pain severity and myocardial injury in ST elevation myocardial infarction: A post-hoc analysis of the AVOID study

Fernando H, Nehme Z, Peter K, Bernard S, Stephenson M, Bray JE, Myles PS, Stub R, Cameron P, Ellims AH, Taylor AJ, Kaye DM, Smith K, Stub D

(2021), International journal of cardiology. Heart & vasculature, 37, 100899

DOI: 10.1016/j.ijcha.2021.100899

Out-of-hospital cardiac arrest outcomes in emergency departments

Kempster K, Howell S, Bernard S, Smith K, Cameron P, Finn J, Stub D, Morley P, Bray J

(2021), Resuscitation, 166, 21-30

DOI: 10.1016/j.resuscitation.2021.07.003

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