Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Severe left ventricular hypertrophy and marked cardiac fibrosis in Danon disease

Stokes MB, Taylor AJ, McLean CA, D'Arcy CE, Mariani JA

(2016), Int J Cardiol, 221,

Genome-wide meta-analyses of breast, ovarian, and prostate cancer association studies identify multiple new susceptibility loci shared by at least two cancer types

Kar SP, Beesley J, Amin Al Olama A, Michailidou K, Tyrer J, Kote-Jarai Z, Lawrenson K, Lindstrom S, Ramus SJ, Thompson DJ; ABCTB Investigators., Kibel AS, Dansonka-Mieszkowska A, Michael A, Dieffenbach AK, Gentry-Maharaj A, Whittemore AS, Wolk A, Monteiro

(2016), Cancer Discov, 6(9),

Synthesis of Oxorhenium(V) and Oxotechnetium(V) complexes that bind to amyloid-β plaques

Hayne DJ, White JM, McLean CA1, Villemagne VL, Barnham KJ, Donnelly PS

(2016), Inorg Chem, 55(16),

Genetically predicted Body Mass Index and breast cancer risk: Mendelian randomization analyses of data from 145,000 women of European descent

Guo Y, Warren Andersen S, Shu XO, Michailidou K, Bolla MK, Wang Q, Garcia-Closas M, Milne RL, Schmidt MK, Chang-Claude J, Dunning A, Bojesen SE, Ahsan H, Aittomäki K, Andrulis IL, Anton-Culver H, Arndt V, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bogdanov

(2016), PLoS Med, 13(8),

Transferrin protects against Parkinsonian neurotoxicity and is deficient in Parkinson’s substantia nigra

Ayton S, Lei P, McLean C, Bush AI, Finkelstein DI

(2016), Signal Transduct Targeted Ther, 1(2016),

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

Southey MC, Goldgar DE, Winqvist R, Pylkäs K, Couch F, Tischkowitz M, Foulkes WD, Dennis J, Michailidou K, van Rensburg EJ, Heikkinen T, Nevanlinna H, Hopper JL, DÖrk T, Claes KB, Reis-Filho J, Teo ZL, Radice P, Catucci I, Peterlongo P, Tsimiklis H, Odefr

(2016), J Med Genet, 53(12),

Nigral dopaminergic PAK4 prevents neurodegeneration in rat models of Parkinson's disease

Won SY, Park MH, You ST, Choi SW, Kim HK, McLean C, Bae SC, Kim SR, Jin BK, Lee KH, Shin EY, Kim EG

(2016), Sci Transl Med, 8(367),

Rubidium and potassium levels are altered in Alzheimer's disease brain and blood but not in cerebrospinal fluid

Roberts BR, Doecke JD, Rembach A, Yévenes LF, Fowler CJ, McLean CA, Lind M, Volitakis I, Masters CL, Bush AI, Hare DJ; AIBL research group

(2016), Acta Neuropathol Commun, 4(1),

Isavuconazole as salvage therapy for mucormycosis

Graves R, Morrissey CO, Wei A, Coutsouvelis J, Ellis S, Pham A, Gooi J, Ananda-Rajah M

(2016), Med Mycol Case Rep, 11,

An assessment of clinical pathways and missed opportunities for the diagnosis of nodular melanoma versus superficial spreading melanoma

Cicchiello M, Lin MJ, Pan Y, McLean C, Kelly JW

(2016), Australas J Dermatol, 57(2),

Interferon beta-1a long-term therapy related to pulmonary arterial hypertension in multiple sclerosis patients

Fok A, Williams T, McLean CA, Butler E

(2016), Mult Scler J, 22(11),

Testicular loss following bacterial epididymo-orchitis:case report and literature review

Fehily SR, Trubiano JA, McLean C, Teoh BW, Grummet JP, Cherry CL, Vujovic O

(2015), Can Urol Assoc J, 9(3-4), E148-51

INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival

Rynkiewicz NK, Fedele CG, Chiam K, Gupta R, Kench JG, Ooms LM, McLean CA, Giles GG, Horvath LG, Mitchell CA

(2015), Prostate, 75(1), 92-102

Probable fenofibrate-induced acute generalized exanthematous pustulosis

Power AE, Graudins LV, McLean CA, Hopper I

(2015), Am J Health Syst Pharm, 72(23), 2061-3

Immunological markers for prognostication in cytogenetically normal acute myeloid leukemia

Ling VY, Lee D, McQuilten Z, Avery S, Low M, Cody SH, Nguyen T, McLean C, Gorniak M, Wei A, Ting SB

(2015), Am J Hematol, 90(12), E219-20

Autoimmune disease leading to pulmonary AL amyloidosis and pulmonary hypertension

Ellender CM, McLean C, Williams TJ, Snell GI, Whitford HM

(2015), Respirol Case Rep, 3(2), 78-81

Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model

Brown FC, Conway AJ, Cerruti L, Collinge JE, McLean C, Wiley JS, Kile BT, Jane SM, Curtis DJ

(2015), Blood, 126(26), 2863-70

Tools for translational epigenetic studies involving formalin-fixed paraffin-embedded human tissue: applying the Infinium HumanMethyation450 Beadchip assay to large population-based studies

Wong EM, Joo JE, McLean CA, Baglietto L, English DR, Severi G, Hopper JL, Milne RL, FitzGerald LM, Giles GG, Southey MC

(2015), BMC Res Notes, 8, 543

Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS

Soo KY, Halloran M, Sundaramoorthy V, Parakh S, Toth RP, Southam KA, McLean CA, Lock P, King A, Farg MA, Atkin JD

(2015), Acta Neuropathol, 130(5), 679-97

The inositol polyphosphate 5-phosphatase PIPP regulates AKT1-dependent breast cancer growth and metastasis

Ooms LM, Binge LC, Davies EM, Rahman P, Conway JR, Gurung R, Ferguson DT, Papa A, Fedele CG, Vieusseux JL, Chai RC, Koentgen F, Price JT, Tiganis T, Timpson P, McLean CA, Mitchell CA

(2015), Cancer Cell, 28(2), 155-69

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