Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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How I treat acute myeloid leukemia in the era of new drugs

DiNardo CD, Wei AH

(2020), Blood, 135(2), 85-96

DOI: 10.1182/blood.2019001239

Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia

DiNardo CD, Jonas BA, Pullarkat V, Thirman MJ, Garcia JS, Wei AH, Konopleva M, Döhner H, Letai A, Fenaux P, Koller E, Havelange V, Leber B, Esteve J, Wang J, Pejsa V, Hájek R, Porkka K, Illés Á, Lavie D, Lemoli RM, Yamamoto K, Yoon SS, Jang JH, Yeh SP, Turgut M, Hong WJ, Zhou Y, Potluri J, Pratz KW

(2020), NEW ENGL J MED, 383(7), 617-29

DOI: 10.1056/NEJMoa2012971

notuzumab ozogamicin resistance associated with a novel CD22 truncating mutation in a case of B-acute lymphoblastic leukaemia

Ryland GL, Barraclough A, Fong CY, Fleming S, Bajel A, Hofmann O, Westerman D, Grimmond S, Blombery P

(2020), Brit J Haematol, 191(1), 123-6

DOI: 10.1111/bjh.16949

Cotargeting BCL-2 and MCL-1 in high-risk B-ALL

Moujalled DM, Hanna DT, Hediyeh-Zadeh S, Pomilio G, Brown L, Litalien V, Bartolo R, Fleming S, Chanrion M, Banquet S, Maragno AL, Kraus-Berthier L, Schoumacher M, Mullighan CG, Georgiou A, White CA, Lessene G, Huang DCS, Roberts AW, Geneste O, Rasmussen L, Davis MJ, Ekert PG, Wei A, Ng AP, Khaw SL

(2020), Blood Adv, 4(12), 2762-7

DOI: 10.1182/bloodadvances.2019001416

Development and Validation of a Population-Pharmacokinetic Model for Rurioctacog Alfa Pegol (Adynovate®): A Report on Behalf of the WAPPS-Hemo Investigators Ad Hoc Subgroup

Chelle P, Yeung CHT, Croteau SE, Lissick J, Balasa V, Ashburner C, Park YS, Bonanad S, Megías-Vericat JE, Nagao A, Wynn T, Corrales-Medina F, Tran H, Sharathkumar A, Chitlur M, Sarmiento S, Edginton A, Iorio A

(2020), Clin Pharmacokinet, 59(2), 245-56

DOI: 10.1007/s40262-019-00809-6

The Australian experience with switching to extended half-life factor VIII and IX concentrates: On behalf of the Australian Haemophilia Centre Directors' Organisation

Brennan Y, Parikh S, McRae S, Tran H

(2020), Haemophilia, 26(3), 529-35

DOI: 10.1111/hae.13970

Incidence of residual perfusion defects by lung scintigraphy in patients treated with rivaroxaban compared with warfarin for acute pulmonary embolism

Lim MS, Nandurkar D, Jong I, Cummins A, Tran H, Chunilal S

(2020), J THROMB THROMBOLYS, 49(2), 220-7

DOI: 10.1007/s11239-019-01944-4

Risk Stratification of Acute Pulmonary Embolism and Determining the Effect on Chronic Cardiopulmonary Complications: The REACH Study

Stevens H, Fang W, Clements W, Bloom J, McFadyen J, Tran H

(2020), TH Open, 40(1), e45-50

DOI: 10.1055/s-0040-1708558

Ischaemic stroke and transient ischaemic attack on anticoagulants: outcomes in the era of direct oral anticoagulants

Valente M, Leung S, Wu P, Oh DH, Tran H, Choi PMC

(2020), Intern Med J, 50(1), 110-3

DOI: 10.1111/imj.14652

Predicting the Risk of Recurrent Venous Thromboembolism: Current Challenges and Future Opportunities

Stevens H, Peter K, Tran H, McFadyen J

(2020), J Clin Med, 9(5), 1582

DOI: 10.3390/jcm9051582

Safety and Efficacy of Direct Oral Anticoagulants for Atrial Fibrillation in Patients with Renal Impairment

Jang SM, Bahjri K, Tran H

(2020), Pharmacy (Basel), 8(1), 30

DOI: 10.3390/pharmacy8010030

Interlaboratory validation of apixaban levels in ex vivo patient samples using a chromogenic anti-factor Xa assay

Singh J, Ong DM, Ling V, Lim MS, Malan E, Servadei P, Wallis A, Kelsey G, Chunilal S, Tran H

(2020), Int J Lab Hematol, 42(1), e23-6

Metastatic melanoma presenting as intravenous tumour thrombus

Nguyen J, Clements W, McLean C, Haydon A, Moore M, Yap KS, Mar V, Shackleton M

(2020), J MED IMAG RADIAT ON, 64(6), 814-6

DOI: 10.1111/1754-9485.13019

Characterization of the pathoimmunology of necrotizing enterocolitis reveals novel therapeutic opportunities

Cho, Steven X.; Rudloff, Ina; Lao, Jason C.; Pang, Merrin A.; Goldberg, Rimma; Bui, Christine B.; McLean, Catriona A.; Stock, Magdalena; Klassert, Tilman E.; Slevogt, Hortense; Mangan, Niamh E.; Cheng, Wei; Fischer, Doris; Gfroerer, Stefan; Sandhu, Manjee

(2020), NAT COMMUN, 11(1), 5794

DOI: 10.1038/s41467-020-19400-w

A 40-Year-Old Man with Persistent Febrile Neutropenia and Subsequent Rash

Meher-Homji, Zaal; North, Daniel; Stewart, James D.; Moir, Diana; Kalff, Anna; Fleming, Shaun; Ananda-Rajah, Michelle R.; Fuller, Andrew; Morrissey, C. Orla

(2020), CLIN INFECT DIS, 71(12), 3260-3262.

DOI: 10.1093/cid/ciaa562

Diagnostic testing for COVID-19

Griffin, David W.J.; Bramwell, Eliza; Cheng, Allen C.; Spelman, Denis W.

(2020), INTERN MED J, 50(12), 1594-1595.

DOI: 10.1111/imj.15083

RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML

Brown, Anna L.; Arts, Peer; Carmichael, Catherine L.; Babic, Milena; Dobbins, Julia; Chong, Chan Eng; Schreiber, Andreas W.; Feng, Jinghua; Phillips, Kerry; Wang, Paul P.S.; Ha, Thuong; Homan, Claire C.; King-Smith, Sarah L.; Rawlings, Lesley; Vakulin, Ca

(2020), BLOOD ADV, 4(6), 1131-1144.

DOI: 10.1182/bloodadvances.2019000901

Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML

DiNardo, C. D.; Tiong, I. S.; Quaglieri, A.; MacRaild, S.; Loghavi, S.; Brown, F. C.; Thijssen, R.; Pomilio, G.; Ivey, A.; Salmon, J. M.; Glytsou, C.; Fleming, S. A.; Zhang, Q.; Ma, H.; Patel, K. P.; Kornblau, S. M.; Xu, Z.; Chua, C. C.; Chen, Xufeng; Blo

(2020), BLOOD, 135(11), 791-803.

DOI: 10.1182/BLOOD.2019003988

Clinical acceleration of jak2 p.v617f driven myeloproliferative disease due to a new uncommon homozygous mpl p.y591d mutation

Ong, Jeremy; Lin, Jane I.; Mitchell, Helen; Morgan, Susan; Perkins, Andrew C.

(2020), HAEMATOLOGICA, 105(8), E428-E431.

DOI: 10.3324/haematol.2020.250969

Chemotherapy and Venetoclax in Elderly Acute Myeloid Leukemia Trial (CAVEAT)

Chua, Chong Chyn; Roberts, Andrew W.; Reynolds, John; Fong, Chun Yew; Ting, Stephen B.; Salmon, Jessica M.; MacRaild, Sarah; Ivey, Adam; Tiong, Ing Soo; Fleming, Shaun; Brown, Fiona C.; Loo, Sun; Majewski, Ian J.; Bohlander, Stefan K.; Wei, Andrew H.

(2020), J CLIN ONCOL, 38(30), 3506-3517.

DOI: 10.1200/JCO.20.00572

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