Research publications | Alfred Health

Role of purinergic signalling in endothelial dysfunction and thrombo-inflammation in ischaemic stroke and cerebral small vessel disease

Lee, Natasha Ting; Ong, Lin Kooi; Gyawali, Prajwal; Nassir, Che Mohd Nasril Che Mohd; Mustapha, Muzaimi; Nandurkar, Harshal H.; Sashindranath, Maithili

(2021), BIOMOLECULES, 11(7), 994

DOI: 10.3390/biom11070994

Effects of water stably-enriched with oxygen as a novel method of tissue oxygenation on mitochondrial function, and as adjuvant therapy for type 2 diabetes in a randomized placebo-controlled trial

Khoo, Joan; Hagemeyer, Christoph; Henstridge, Darren C.; Kumble, Sumukh; Wang, Ting-Yi; Xu, Rong; Gani, Linsey; King, Thomas; Soh, Shui-Boon; Puar, Troy; Au, Vanessa; Tan, Eberta; Tay, Tunn Lin; Kam, Carmen; Teo, Eng-Kiong

(2021), PLOS ONE, 16(7), e0254619

DOI: 10.1371/journal.pone.0254619

Plasminogen: an enigmatic zymogen

Keragala, Charithani B.; Medcalf, Robert L.

(2021), BLOOD, 137(21), 2881-2889

DOI: 10.1182/blood.2020008951

Broad-based influenza-specific cd8+ t cell response without the typical immunodominance hierarchy and its potential implication

Huang, Miaojuan; Xu, Rong; Triffon, Cristina; Mifsud, Nicole; Chen, Weisan

(2021), VIRUSES-BASEL, 13(6), 1080

DOI: 10.3390/v13061080

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

Hogg, Simon J.; Motorna, Olga; Cluse, Leonie A.; Johanson, Timothy M.; Coughlan, Hannah D.; Raviram, Ramya; Myers, Robert M.; Costacurta, Matteo; Todorovski, Izabela; Pijpers, Lizzy; Bjelosevic, Stefan; Williams, Tobias; Huskins, Shannon N.; Kearney, Cono

(2021), MOL CELL, 81(10), 2183-2200e13

DOI: 10.1016/j.molcel.2021.04.015

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro

Hoefer, Thomas; Rana, Akshita; Niego, Be'eri; Jagdale, Shweta; Albers, Hugo J.; Gardiner, Elizabeth E.; Andrews, Robert K.; van der Meer, Andries D.; Hagemeyer, Christoph e.; Westein, Erik

(2021), HAEMATOLOGICA, 106(11), 2874-2884

DOI: 10.3324/haematol.2020.250761

Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome

Greening, David W.; Notaras, Michael; Chen, Maoshan; Xu, Rong; Smith, Joel D.; Cheng, Lesley; Simpson, Richard J.; Hill, Andrew F.; van den Buuse, Maarten

(2021), MOL PSYCHIATR, 26(8), 4431-4447

DOI: 10.1038/s41380-019-0617-8

Deletion of IKK2 in haematopoietic cells of adult mice leads to elevated interleukin-6, neutrophilia and fatal gastrointestinal inflammation

Fischer, Karla C.; Daunt, Carmel P.; Tremblay, Cédric S.; Dias, Sheila; Vince, James E.; Jabbour, Anissa M.

(2021), CELL DEATH DIS, 12(1), 28

DOI: 10.1038/s41419-020-03298-9

Collagen-targeted peptides for molecular imaging of diffuse cardiac fibrosis

Ezeani, Martin; Noor, Asif; Alt, Karen; Lal, Sean; Donnelly, Paul S.; Hagemeyer, Christoph E.; Niego, Be’Eri

(2021), J AM HEART ASSOC, 10(18), e022139

DOI: 10.1161/JAHA.121.022139

Important factors in implementation of lineage-specific chimerism analysis for routine use

Das, Tongted P.; Kipp, David A.; Kliman, David S.; Patil, Sushrut S.; Curtis, David J.; O’Brien, Maureen E.; Swain, Michael I.; Widjaja, Jacqueline M.L.; Cooke, Jade L.; Ziino, Melinda N.; Spencer, Andrew

(2021), BONE MARROW TRANSPL, 56(4), 946-948

DOI: 10.1038/s41409-020-01089-6

CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation

Chüeh, Anderly C.; Advani, Gahana; Foroutan, Momeneh; Smith, Jai; Ng, Nadia; Nandurkar, Harshal; Lio, Daisy S.; Zhu, Hong Jian; Chong, Yuh Ping; Verkade, Heather; Fujita, Donald J.; Bjorge, Jeffrey; Basheer, Faiza; Lim, Jet Phey; Luk, Ian; Dhillon, Amarde

(2021), ONCOGENE, 40, 3015-3029

DOI: 10.1038/s41388-021-01755-z

The Patients’ Perspective: Hematological Cancer Patients' Experiences of Adverse Events as Part of Care

Bryant, Jamie; Carey, Mariko; Sanson-Fisher, Rob; Turon, Heidi; Wei, Andrew; Kuss, Bryone

(2021), J PATIENT SAF, 17(5), e387-e392

DOI: 10.1097/PTS.0000000000000347

Serine Biosynthesis Is a Metabolic Vulnerability in FLT3-ITD-Driven Acute Myeloid Leukemia

Bjelosevic, Stefan; Gruber, Emily; Newbold, Andrea; Shembrey, Carolyn; Devlin, Jennifer R.; Hogg, Simon J.; Kats, Lev; Todorovski, Izabela; Fan, Zheng; Abrehart, Thomas C.; Pomilio, Giovanna; Wei, Andrew; Gregory, Gareth P.; Vervoort, Stephin J.; Brown, K

(2021), CANCER DISCOV, 11(6), 1582-1599

DOI: 10.1158/2159-8290.CD-20-0738

Blood apheresis technologies-a critical review on challenges towards efficient blood separation and treatment

Bacal, Christine Jurene O.; Maina, James W.; Nandurkar, Harshal H.; Khaleel, Maryam; Guijt, Rosanne; Chang, Yung; Dwyer, Karen M.; Dumée, Ludovic F.

(2021), Materials Advances, 2(22), 7210-7236

DOI: 10.1039/d1ma00859e

T-ALL can evolve to oncogene independence

Abdulla, Hesham; Vo, Anh; Shields, Benjamin J.; Davies, Tenae J.; Jackson, Jacob T.; Alserihi, Raed; Viney, Elizabeth M.; Wong, Tin; Yan, Feng; Wong, Nicholas C.; Demoen, Lisa; Curtis, David J.; Alexander, Warren S.; Van Vlierberghe, Pieter; Dickins, Ross

(2021), LEUKEMIA, 35, 2205–2219

DOI: 10.1038/s41375-021-01120-9

AAA stewardship: managing high-risk medications with dedicated antimicrobial, anticoagulation and analgesic stewardship programs

Thuy Bui, Hadley Bortz, Kelly Cairns, Linda Graudins, Carmela Corallo, Alex Konstantatos, Huyen Tran, Allen Cheng, Michael Dooley

(2021), Journal of Pharmacy Practice and Research, 51(4), 342-7

DOI: 10.1002/jppr.1716

Real-World Rates of Bleeding, Factor VIII Use, and Quality of Life in Individuals with Severe Haemophilia A Receiving Prophylaxis in a Prospective, Non-Interventional Study

Kenet G, Chen YC, Lowe G, Percy C, Tran H, von Drygalski A, Trossaërt M, Reding M, Oldenburg J, Mingot-Castellano ME, Park YS, Peyvandi F, Ozelo MC, Mahlangu J, Quinn J, Huang M, Reddy DB, Kim B

(2021), J Clin Med, 10(24), 5959

DOI: 10.3390/jcm10245959

Australian and New Zealand approach to diagnosis and management of vaccine-induced thrombosis and thrombocytopenia

Chen VM, Curnow JL, Tran HA, Choi PY

(2021), MED J AUSTRALIA, 215(6), 245-9.e1

DOI: 10.5694/mja2.51229

Tranexamic acid rapidly inhibits fibrinolysis, yet transiently enhances plasmin generation in vivo

Draxler DF, Zahra S, Goncalves I, Tran H, Hanafi G, Ho H, Keragala CB, Ilich A, Key NS, Myles PS, Medcalf RL

(2021), BLOOD COAGUL FIBRIN, 32(3), 172-9

DOI: 10.1097/MBC.0000000000001008

Acquired haemophilia and haemostatic control with recombinant porcine factor VIII: case series

Campbell S, Mason J, Prasad R, Ambrose H, Hunt S, Tran H

(2021), Intern Med J, 51(2), 215-9

DOI: 10.1111/imj.14773