Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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The EMT Modulator SNAI1 Contributes to AML Pathogenesis via Its Interaction With LSD1

Carmichael, Catherine L.; Wang, Jueqiong; Nguyen, Thao; Kolawole, Oluseyi; Benyoucef, Aissa; De Mazière, Charlotte; Milne, Anna R.; Samuel, Sona; Gillinder, Kevin; Hediyeh-Zadeh, Soroor; Vo, Ngoc; Huang, Yizhou; Knezevic, Kathy; McInnes, William R L; Shie

(2020), BLOOD, 136(8), 957-973.

DOI: 10.1182/blood.2019002548

The Complexity of Trauma-Induced Coagulopathy

Moore, Hunter B.; Walsh, Mark; Kwaan, Hau C.; Medcalf, Robert L.

(2020), SEMIN THROMB HEMOST, 46(2), 114-115.

DOI: 10.1055/s-0040-1702202

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro

Hoefer, Thomas; Rana, Akshita; Niego, Be'eri; Jagdale, Shweta; Albers, Hugo J.; Gardiner, Elizabeth E.; Andrews, Robert K.; van der Meer, Andries D.; Hagemeyer, Christoph e.; Westein, Erik

(2020), HAEMATOLOGICA, 105),

DOI: 10.3324/haematol.2020.250761

Targeting Nanotechnologies for the Treatment of Thrombosis and Cardiovascular Disease

Palazzolo, Jason Sam; Westein, Erik; Hagemeyer, Christoph Eugen; Wang, Ting Yi

(2020), SEMIN THROMB HEMOST, 46(5), 606-621.

DOI: 10.1055/s-0039-1697946

Sperm chromatin structure assay versus sperm chromatin dispersion kits: Technical repeatability and choice of assisted reproductive technology procedure

Vidya Laxme, B.; Stephen, Silviya; Devaraj, Ramyashree; Mahendran, Tara; Mithraprabhu, Sridurga; Bertolla, Ricardo P.

(2020), Clinical and Experimental Reproductive Medicine, 47(4), 277-283.

DOI: 10.5653/cerm.2020.03860

Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells

Tremblay, Cedric S.; Chiu, Sung Kai; Saw, Jesslyn; McCalmont, Hannah; Litalien, Veronique; Boyle, Jacqueline A.; Sonderegger, Stefan E.; Chau, Ngoc; Evans, Kathryn; Cerruti, Loretta; Salmon, Jessica M.; McCluskey, Adam; Lock, Richard B.; Robinson, Phillip

(2020), NAT COMMUN, 11(1), 6211

DOI: 10.1038/s41467-020-20091-6

Single-cell lineage tracing approaches in hematology research: technical considerations

Carrelha, Joana; Lin, Dawn S.; Rodriguez-Fraticelli, Alejo E.; Luis, Tiago C.; Wilkinson, Adam C.; Cabezas-Wallscheid, Nina; Tremblay, Cedric S.; Haas, Simon

(2020), EXP HEMATOL, 89, 26-36.

DOI: 10.1016/j.exphem.2020.07.007

Sex-dependent effects of tranexamic acid on blood-brain barrier permeability and the immune response following traumatic brain injury in mice

Daglas, Maria; Galle, Adam; Draxler, Dominik F.; Ho, Heidi; Liu, Zikou; Sashindranath, Maithili; Medcalf, Robert L.

(2020), J THROMB HAEMOST, 18(10), 2658-2671.

DOI: 10.1111/jth.15015

RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML

Brown, Anna L.; Arts, Peer; Carmichael, Catherine L.; Babic, Milena; Dobbins, Julia; Chong, Chan Eng; Schreiber, Andreas W.; Feng, Jinghua; Phillips, Kerry; Wang, Paul P.S.; Ha, Thuong; Homan, Claire C.; King-Smith, Sarah L.; Rawlings, Lesley; Vakulin, Ca

(2020), BLOOD ADV, 4(6), 1131-1144.

DOI: 10.1182/bloodadvances.2019000901

Rerouting DOT1L inhibitors in leukemia

Dickins, Ross A.

(2020), BLOOD, 136(17), 1900-1901.

DOI: 10.1182/blood.2020007352

Prevalence and distribution of functional splenic tissue after splenectomy

Luu, Sarah; Sheldon, James; Dendle, Claire; Ojaimi, Samar; Jones, Penelope; Woolley, Ian

(2020), INTERN MED J, 50(5), 556-564.

DOI: 10.1111/imj.14621

Plasmin Generation Potential and Recanalization in Acute Ischaemic Stroke; an Observational Cohort Study of Stroke Biobank Samples

Lillicrap, Thomas; Keragala, Charithani B.; Draxler, Dominik F.; Chan, Jilly; Ho, Heidi; Harman, Stevi; Niego, Be'eri; Holliday, Elizabeth; Levi, Christopher R.; Garcia-Esperon, Carlos; Spratt, Neil; Gyawali, Prajwal; Bivard, Andrew; Parsons, Mark W.; Mon

(2020), FRONT NEUROL, 11, 589628

DOI: 10.3389/fneur.2020.589628

Plasma levels of the soluble form of the FcγRIIa receptor vary with receptor polymorphisms and are elevated in rheumatoid arthritis

Qiao, Jianlin; Dunne, Eimear; Wines, Bruce; Kenny, Dermot; McCarthy, Geraldine M.; Hogarth, P. Mark; Xu, Kailin; Andrews, Robert K.; Gardiner, Elizabeth E.

(2020), PLATELETS, 31(3), 392-398.

DOI: 10.1080/09537104.2019.1647527

Placental serotonin systems in pregnancy metabolic complications associated with maternal obesity and gestational diabetes mellitus

Murthi, Padma; Vaillancourt, Cathy

(2020), BBA-MOL BASIS DIS, 1866(2), 165391

DOI: 10.1016/j.bbadis.2019.01.017

Nanomedicine in Thrombosis and Hemostasis

Hagemeyer, Christoph E.; Lisman, Ton; Kwaan, Hau C.

(2020), SEMIN THROMB HEMOST, 46(5), 521-523.

DOI: 10.1055/s-0040-1713680

Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML

DiNardo, C. D.; Tiong, I. S.; Quaglieri, A.; MacRaild, S.; Loghavi, S.; Brown, F. C.; Thijssen, R.; Pomilio, G.; Ivey, A.; Salmon, J. M.; Glytsou, C.; Fleming, S. A.; Zhang, Q.; Ma, H.; Patel, K. P.; Kornblau, S. M.; Xu, Z.; Chua, C. C.; Chen, Xufeng; Blo

(2020), BLOOD, 135(11), 791-803.

DOI: 10.1182/BLOOD.2019003988

Management of the thrombotic risk associated with COVID-19: guidance for the hemostasis laboratory

Hardy, M.; Lecompte, T.; Douxfils, J.; Lessire, S.; Dogné, J. M.; Chatelain, B.; Testa, S.; Gouin-Thibault, I.; Gruel, Y.; Medcalf, R. L.; Ten Cate, H.; Lippi, G.; Mullier, F.

(2020), THROMB J, 18(1), 17

DOI: 10.1186/s12959-020-00230-1

In vitro flow based systems to study platelet function and thrombus formation

Mangin, Pierre H.; Gardiner, Elizabeth E.; Nesbitt, Warwick S.; Kerrigan, Steven W.; Korin, Netanel; Lam, Wilbur A.; Panteleev, Mikhail A.; ,

(2020), J THROMB HAEMOST, 18(3), 748-752.

DOI: 10.1111/jth.14717

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

Fagnan, Alexandre; Bagger, Frederik Otzen; Piqué-Borràs, Maria Riera; Ignacimouttou, Cathy; Caulier, Alexis; Lopez, Cécile K.; Robert, Elie; Uzan, Benjamin; Gelsi-Boyer, Véronique; Aid, Zakia; Thirant, Cécile; Moll, Ute; Tauchmann, Samantha; Kurtovic-Koza

(2020), BLOOD, 136(6), 698-714.

DOI: 10.1182/blood.2019003062

Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia

Straube, Jasmin; Bywater, Megan; Cooper, Leanne; Bruedigam, Claudia; Magor, Graham; Perkins, Andrew; Chalk, Alistair M.; Walkley, Carl R.; Mukhopadhyay, Pamela; Cloonan, Nicole; Lane, Steven W.

(2020), NAT COMMUN, 11(1), 3021

DOI: 10.1038/s41467-020-16840-2

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