Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Genetic predisposition to in situ and invasive lobular carcinoma of the breast

Sawyer E, Roylance R, Petridis C, Brook MN, Nowinski S, Papouli E, Fletcher O, Pinder S, Hanby A, Kohut K, Gorman P, Caneppele M, Peto J, Dos Santos Silva I, Johnson N, Swann R, Dwek M, Perkins KA, Gillett C, Houlston R, Ross G, De Ieso P, Southey MC, Hop

(2014), PLoS Genet, 10(4), e1004285

Do current therapeutic anti-Aβ antibodies for Alzheimer's disease engage the target?

Watt AD, Crespi GA, Down RA, Ascher DB, Gunn A, Perez KA, McLean CA, Villemagne VL, Parker MW, Barnham KJ, Miles LA

(2014), Acta Neuropathol, 127(6), 803-10

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade

Purrington KS, Slettedahl S, Bolla MK, Michailidou K, Czene K, Nevanlinna H, Bojesen SE, Andrulis IL, Cox A, Hall P, Carpenter J, Yannoukakos D, Haiman CA, Fasching PA, Mannermaa A, Winqvist R, Brenner H, Lindblom A, Chenevix-Trench G, Benitez J, Swerdlow

(2014), Hum Mol Genet, 23(22), 6034-46

An objective measure of growth rate using partial biopsy specimens of melanomas that were initially misdiagnosed

Lin MJ, Mar V, McLean C, Kelly JW

(2014), J Am Acad Dermatol, 71(4), 691-7

Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma

Mar VJ, Wong SQ, Logan A, Nguyen T, Cebon J, Kelly JW, Wolfe R, Dobrovic A, McLean C, McArthur GA

(2014), Pigment Cell Melanoma Res, 27(6), 1117-25

Anti-Aβ antibody target engagement: a response to Siemers et al

Watt AD, Crespi GA, Down RA, Ascher DB, Gunn A, Perez KA, McLean CA, Villemagne VL, Parker MW, Barnham KJ, Miles LA

(2014), Acta Neuropathol, 128(4), 611-4

Characteristics and associations of high-mitotic-rate melanoma

Shen S, Wolfe R, McLean CA, Haskett M, Kelly JW

(2014), JAMA Dermatol, 150(10), 1048-55

Oral myeloid sarcoma: two case reports

Yap M, Hewson I, McLean C, Ciciulla J

(2014), Aust Dent J, 59(4), 511-5

β-amyloid in biological samples: not all Aβ detection methods are created equal

Adlard PA, Li QX, McLean C, Masters CL, Bush AI, Fodero-Tavoletti M, Villemagne V, Barnham KJ

(2014), Front Aging Neurosci, 6, 203

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

Ghoussaini M, Edwards SL, Michailidou K, Nord S, Cowper-Sal Lari R, Desai K, Kar S, Hillman KM, Kaufmann S, Glubb DM, Beesley J, Dennis J, Bolla MK, Wang Q, Dicks E, Guo Q, Schmidt MK, Shah M, Luben R, Brown J, Czene K, Darabi H, Eriksson M, Klevebring D,

(2014), Nat Commun, 4, 4999

MicroRNA related polymorphisms and breast cancer risk

Khan S, Greco D, Michailidou K, Milne RL, Muranen TA, Heikkinen T, Aaltonen K, Dennis J, Bolla MK, Liu J, Hall P, Irwanto A, Humphreys K, Li J, Czene K, Chang-Claude J, Hein R, Rudolph A, Seibold P, Flesch-Janys D, Fletcher O, Peto J, dos Santos Silva I,

(2014), PLoS One, 9(11), e109973

Epigenome-wide methylation in DNA from peripheral blood as a marker of risk for breast cancer

Severi G, Southey MC, English DR, Jung CH, Lonie A, McLean C, Tsimiklis H, Hopper JL, Giles GG, Baglietto L

(2014), Breast Cancer Res Treat, 148(3), 665-73

Mutations in RAB39B cause X-linked intellectual disability and early-onset Parkinson disease with α-synuclein pathology

Wilson GR, Sim JC, McLean C, Giannandrea M, Galea CA, Riseley JR, Stephenson SE, Fitzpatrick E, Haas SA, Pope K, Hogan KJ, Gregg RG, Bromhead CJ, Wargowski DS, Lawrence CH, James PA, Churchyard A, Gao Y, Phelan DG, Gillies G, Salce N, Stanford L, Marsh AP

(2014), Am J Hum Genet, 95(6), 729-35

A 67-year-old man with painful diplopia: question

Fok A, McLean CA, Chandra RV, Seneviratne U

(2014), J Clin Neurosci, 21(12), 2227, 2260

Creutzfeldt-Jakob disease surveillance in Australia, update to December 2013

Klug GM, Boyd A, Sarros S, Stehmann C, Simpson M, McLean CA, Masters CL, Collins SJ

(2014), Commun Dis Intell Q Rep, 38(4), E348-55

Low-flow hypothermic crystalloid perfusion is superior to cold storage during prolonged heart preservation

Ou R, Lim YW, Choong JW, Esmore DS, Salamonsen RF, McLean C, Forbes J, Bailey M, Rosenfeldt FL

(2014), Transplant Proc, 46(10), 3309-13

A comprehensive evaluation of myocardial fibrosis in hypertrophic cardiomyopathy with cardiac magnetic resonance imaging: linking genotype with fibrotic phenotype

Ellims AH, Iles LM, Ling LH, Chong B, Macciocca I, Slavin GS, Hare JL, Kaye DM, Marasco SF, McLean CA, James PA, du Sart D, Taylor AJ

(2014), Eur Heart J Cardiovasc Imaging, 15(10), 1108-16

CMV sinusitis in a HIV-negative renal transplant recipient

Gujadhur A, Thomson N, Aung AK, Mclean C, Menahem S

(2014), Transplantation, 97(9), e55-7

Idiopathic granulomatous hypophysitis: a systematic review of 82 cases in the literature

Hunn BH, Martin WG, Simpson S Jr, McLean CA

(2014), Pituitary, 17(4), 357-65

Identification of FHL1 as a therapeutic target for Duchenne muscular dystrophy

D'Arcy CE, Feeney SJ, McLean CA, Gehrig SM, Lynch GS, Smith JE, Cowling BS, Mitchell CA, McGrath MJ

(2014), Hum Mol Genet, 23(3), 618-36

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