Research publications | Alfred Health

Phase 2 study of all-oral ixazomib, cyclophosphamide and low-dose dexamethasone for relapsed/refractory multiple myeloma

Kumar, Shaji K.; Grzasko, Norbert; Delimpasi, Sosana; Jedrzejczak, Wieslaw W.; Grosicki, Sebastian; Kyrtsonis, Marie Christine; Spencer, Andrew; Gupta, Neeraj; Teng, Zhaoyang; Byrne, Catriona; Labotka, Richard; Dimopoulos, Meletios A.

(2019), BRIT J HAEMATOL, 184(4), 536-546.

DOI: 10.1111/bjh.15679

Tranexamic acid modulates the immune response and reduces postsurgical infection rates

Draxler, Dominik F.; Yep, Kah; Hanafi, Gryselda; Winton, Anoushka; Daglas, Maria; Ho, Heidi; Sashindranath, Maithili; Wutzlhofer, Lisa M.; Forbes, Andrew; Goncalves, Isaac; Tran, Huyen A.; Wallace, Sophia; Plebanski, Magdalena; Myles, Paul S.; Medcalf, Robert L.

(2019), Blood Adv, 3(10), 1598-1609.

DOI: 10.1182/bloodadvances.2019000092

Tranexamic acid modulates the cellular immune profile after traumatic brain injury in mice without hyperfibrinolysis

Draxler, Dominik F.; Daglas, Maria; Fernando, Anushka; Hanafi, Gryselda; McCutcheon, Fiona; Ho, Heidi; Galle, Adam; Gregory, Julia; Larsson, Pia; Keragala, Charithani; Wright, David K.; Tavancheh, Elnaz; Au, Amanda E.; Niego, Be'eri; Wilson, Kirsty; Plebanski, Magdalena; Sashindranath, Maithili; Medcalf, Robert L.

(2019), J THROMB HAEMOST, 17(12), 2174-2187.

DOI: 10.1111/jth.14603

Shared roles for Scl and Lyl1 in murine platelet production and function

Chiu, Sung K.; Orive, Stephanie L.; Moon, Mitchell J.; Saw, Jesslyn; Ellis, Sarah; Kile, Benjamin T.; Huang, Yizhou; Chacon, Diego; Pimanda, John E.; Beck, Dominik; Hamilton, Justin R.; Tremblay, Cedric S.; Curtis, David J.

(2019), BLOOD, 134(10), 826-835.

DOI: 10.1182/blood.2019896175

Antiphospholipid syndrome: a clinical review

Mezhov, Veronica; Segan, Julian D.; Tran, Huyen; Cicuttini, Flavia M.

(2019), MED J AUSTRALIA, 211(4), 184-188.

DOI: 10.5694/mja2.50262

T-PA suppresses the immune response and aggravates neurological deficit in a murine model of ischemic stroke

Draxler, Dominik F.; Lee, Felix; Ho, Heidi; Keragala, Charithani B.; Medcalf, Robert L.; Niego, Be'eri

(2019), FRONT IMMUNOL, 10, MAR

DOI: 10.3389/fimmu.2019.00591

Shear-Dependent Platelet Aggregation

Rana, Akshita; Westein, Erik; Niego, Be'eri; Hagemeyer, Christoph E.

(2019), Front Cardiovasc Med, 6, 141

DOI: 10.3389/fcvm.2019.00141

Novel stenotic microchannels to study thrombus formation in shear gradients

Lui, Mathew; Gardiner, Elizabeth E.; Arthur, Jane F.; Pinar, Isaac; Lee, Woei Ming; Ryan, Kris; Carberry, Josie; Andrews, Robert K.

(2019), INT J MOL SCI, 20(12), 2967

DOI: 10.3390/ijms20122967

Corrupted DNA-binding specificity and ectopic transcription underpin dominant neomorphic mutations in KLF/SP transcription factors

Ilsley, Melissa D.; Huang, Stephen; Magor, Graham W.; Landsberg, Michael J.; Gillinder, Kevin R.; Perkins, Andrew C.

(2019), BMC GENOMICS, 20(1), 417

DOI: 10.1186/s12864-019-5805-z

Genomic subtyping and therapeutic targeting of acute erythroleukemia

Iacobucci, Ilaria; Wen, Ji; Meggendorfer, Manja; Choi, John K.; Shi, Lei; Pounds, Stanley B.; Carmichael, Catherine L.; Masih, Katherine E.; Morris, Sarah M.; Lindsley, R. Coleman; Janke, Laura J.; Alexander, Thomas B.; Song, Guangchun; Qu, Chunxu; Li, Yongjin; Payne-Turner, Debbie; Tomizawa, Daisuke; Kiyokawa, Nobutaka; Valentine, Marcus; Valentine, Virginia; Basso, Giuseppe; Locatelli, Franco; Enemark, Eric J.; Kham, Shirley K.Y.; Yeoh, Allen E.J.; Ma, Xiaotu; Zhou, Xin; Sioson, Edgar; Rusch, Michael; Ries, Rhonda E.; Stieglitz, Elliot; Hunger, Stephen P.; Wei, Andrew H.; To, L. Bik; Lewis, Ian D.; D’Andrea, Richard J.; Kile, Benjamin T.; Brown, Anna L.; Scott, Hamish S.; Hahn, Christopher N.; Marlton, Paula; Pei, Deqing; Cheng, Cheng; Loh, Mignon L.; Ebert, Benjamin L.; Meshinchi, Soheil; Haferlach, Torsten; Mullighan, Charles G.

(2019), NAT GENET, 51(4), 694-704.

DOI: 10.1038/s41588-019-0375-1

Meta-analysis of Grainyhead-like dependent transcriptional networks

Mathiyalagan, Nishanthi; Miles, Lee B.; Anderson, Peter J.; Wilanowski, Tomasz; Grills, Brian L.; McDonald, Stuart J.; Keightley, M. Cristina; Charzynska, Agata; Dabrowski, Michal; Dworkin, Sebastian

(2019), GENES-BASEL, 10(11, 876

DOI: 10.3390/genes10110876

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

Liu, You Dong; Yu, Liang; Ying, Le; Balic, Jesse; Gao, Hugh; Deng, Nian Tao; West, Alison; Yan, Feng; Ji, Cheng Bo; Gough, Daniel; Tan, Patrick; Jenkins, Brendan J.; Li, Ji Kun

(2019), INT J CANCER, 144(12), 3056-3069.

DOI: 10.1002/ijc.32060

Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1

Deuss, Felix A; Watson, Gabrielle M; Goodall, Katharine J; Leece, Isobel; Chatterjee, Sayantani; Fu, Zhihui; Thaysen-Andersen, Morten; Andrews, Daniel M; Rossjohn, Jamie; Berry, Richard

(2019), J BIOL CHEM, 294(33), 12534-12546.

DOI: 10.1074/jbc.RA119.009261

Activated CD8+ T Cells Cause Long-Term Neurological Impairment after Traumatic Brain Injury in Mice

Daglas, Maria; Draxler, Dominik F.; Ho, Heidi; McCutcheon, Fiona; Galle, Adam; Au, Amanda E.; Larsson, Pia; Gregory, Julia; Alderuccio, Frank; Sashindranath, Maithili; Medcalf, Robert L.

(2019), CELL REP, 29(5), 1178-1191.e6.

DOI: 10.1016/j.celrep.2019.09.046

Ligand-Functionalized Poly(ethylene glycol) Particles for Tumor Targeting and Intracellular Uptake

Cui, Jiwei; Alt, Karen; Ju, Yi; Gunawan, Sylvia T.; Braunger, Julia A.; Wang, Ting Yi; Dai, Yunlu; Dai, Qiong; Richardson, Joseph J.; Guo, Junling; Björnmalm, Mattias; Hagemeyer, Christoph E.; Caruso, Frank

(2019), BIOMACROMOLECULES, 20(9), 3592-3600.

DOI: 10.1021/acs.biomac.9b00925

Carbohydrates@MOFs

Astria, Efwita; Thonhofer, Martin; Ricco, Raffaele; Liang, Weibin; Chemelli, Angela; Tarzia, Andrew; Alt, Karen; Hagemeyer, Christoph E.; Rattenberger, Johannes; Schroettner, Hartmuth; Wrodnigg, Tanja; Amenitsch, Heinz; Huang, David M.; Doonan, Christian J.; Falcaro, Paolo

(2019), MATER HORIZ, 6(5), 969-977.

DOI: 10.1039/c8mh01611a

Active Micropump-Mixer for Rapid Antiplatelet Drug Screening in Whole Blood

Szydzik, Crispin; Brazilek, Rose J.; Akbaridoust, Farzan; De Silva, Charitha; Moon, Mitchell; Marusic, Ivan; Ooi, Andrew S.H.; Nandurkar, Harshal H.; Hamilton, Justin R.; Mitchell, Arnan; Nesbitt, Warwick S.

(2019), ANAL CHEM, 91(16), 10830-10839.

DOI: 10.1021/acs.analchem.9b02486

Optical frequency comb based system for photonic refractive index sensor interrogation

Knoerzer, Markus; Szydzik, Crispin; Ren, Guanghui; Huertas, Cesar S.; Palmer, Sonya; Tang, Phuong; Nguyen, Thach G.; Bui, Lam; Boes, Andreas; Mitchell, Arnan

(2019), OPT EXPRESS, 27(15), 21532-21545.

DOI: 10.1364/OE.27.021532

Site-Specific Glycation and Chemo-enzymatic Antibody Sortagging for the Retargeting of rAAV6 to Inflamed Endothelium.

Hannah A Pearce, Hongwei Qian, Timothy U Connell, Dexing Huang, Claudia Gottstein, Paul S Donnelly, Karlheinz Peter, Paul Gregorevic, Christoph E Hagemeyer

(2019), MOL THER-METH CLIN D, 14, 261-269

DOI: 10.1016/j.omtm.2019.07.003

Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia.

Mark D McKenzie, Margherita Ghisi, Ethan P Oxley, Steven Ngo, Luisa Cimmino, CÃ©cile Esnault, Ruijie Liu, Jessica M Salmon, Charles C Bell, Nouraiz Ahmed, Michael Erlichster, Matthew T Witkowski, Grace J Liu, Michael Chopin, Aleksandar Dakic, Emilia Simankowicz, Giovanna Pomilio, Tina Vu, Pavle Krsmanovic, Shian Su, Luyi Tian, Tracey M Baldwin, Daniela A Zalcenstein, Ladina DiRago, Shu Wang, Donald Metcalf, Ricky W Johnstone, Ben A Croker, Graeme I Lancaster, Andrew J Murphy, Shalin H Naik, Stephen L Nutt, Vitek Pospisil, Timm Schroeder, Meaghan Wall, Mark A Dawson, Andrew H Wei, Hugues de ThÃ©, Matthew E Ritchie, Johannes Zuber, Ross A Dickins

(2019), Cell stem cell, 2(25), 258-272.e9

DOI: 10.1016/j.stem.2019.07.001