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Alfred Health research outcomes are published in a wide range of peer reviewed journals.
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MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia
Brown, Fiona C.; Still, Eric; Koche, Richard P.; Yim, Christina Y.; Takao, Sumiko; Cifani, Paolo; Reed, Casie; Gunasekera, Shehana; Ficarro, Scott B.; Romanienko, Peter; Mark, Willie; McCarthy, Craig; de Stanchina, Elisa; Gonen, Mithat; Seshan, Venkatraman; Bhola, Patrick; O’Donnell, Conor; Spitzer, Barbara; Stutzke, Crystal; Lavall»e, Vincent Philippe; H»bert, Jos»e; Krivtsov, Andrei V.; Melnick, Ari; Paietta, Elisabeth M.; Tallman, Martin S.; Letai, Anthony; Sauvageau, Guy; Pouliot, Gayle; Levine, Ross; Marto, Jarrod A.; Armstrong, Scott A.; Kentsis, Alex
(2018), Cancer Discov, 8(4), 478-497
The Canonical Wnt/β-catenin Pathway as a Therapeutic Target in Multiple Myeloma
Savvidou, Ioanna; Khong, Tiffany; Spencer, Andrew; Alt, Karen Maria
(2018), ARCH MED RES, 6(7), 43480
Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells
Tremblay, Cedric; Saw, Jesslyn; Chiu, Sung Kai; Wong, Nicholas C.; Tsyganov, Kirill; Ghotb, Sarah; Graham, Alison N; Yan, Feng; Guirguis, Andrew; Sonderegger, Stefan; Lee, Nicole; Kalitsis, Paul; Reynolds, John; Ting, Stephen; Powell, David; Jane, Stephen; Curtis, David
(2018), Nat Commun, 9(1), 3535
A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8
Bouhy, Delphine; Juneja, Manisha; Katona, Istvan; Holmgren, Anne; Asselbergh, Bob; De Winter, Vicky; Hochepied, Tino; Goossens, Steven; Haigh, Jody J.; Libert, Claude; Ceuterick-de Groote, Chantal; Irobi, Joy; Weis, Joachim; Timmerman, Vincent
(2018), Acta Neuropathol, 135(1), 131-148
Contemporary analysis of functional immune recovery to opportunistic and vaccine-preventable infections after allogeneic haemopoietic stem cell transplantation
De Silva, Harini; Ffrench, Rosemary Ann; Korem, Maya; Orlowski-Oliver, Eva; Curtis, David John; Spencer, Andrew; Avery, Sharon; Patil, Sushrut; Morrissey, Catherine Orla
(2018), Clin Transl Immunology, 7(10), e1040
DOI: 10.1002/cti2.1040
A comparison of global coagulation assays between normal controls and patients with thrombocytopenia
Lim, Hui Yin; Leung, Patrick; Manitta, Vanessa; Nandurkar, Harshal; Ho, Prahlad
(2018), INT J LAB HEMATOL, 41(2), 184-191
DOI: 10.1111/ijlh.12941
Perinatal lethality of Par4–/– mice delivered by primiparous dams reveals spontaneous bleeding in mice without platelet thrombin receptor function
French, Shauna L.; Hamilton, Justin R.
(2018), Platelets, 29(2), 196-198
Thrombin generation estimates the anticoagulation effect of direct oral anticoagulants with significant interindividual variability observed
Rigano, Joseph; Ng, Cheryl; Nandurkar, Harshal Hanumant; Ho, Prahlad
(2018), Blood Coagul Fibrinolysis, 29(2), 148-154
An evaluation of global coagulation assays in myeloproliferative neoplasm
Lim, Hui Y.; Ng, Cheryl; Rigano, Joseph; Tacey, Mark Alan; Donnan, Geoffrey; Nandurkar, Harshal Hanumant; Ho, Prahlad Wei Soon
(2018), Blood Coagul Fibrinolysis, 29(3), 300-306
Carfilzomib–dexamethasone versus subcutaneous or intravenous bortezomib in relapsed or refractory multiple myeloma
Goldschmidt, Hartmut; Moreau, Philippe; Ludwig, Heinz; Niesvizky, Ruben; Chng, Wee Joo; Joshua, Douglas; Weisel, Katja; Spencer, Andrew; Orlowski, Robert Z.; Feng, Shibao; Iskander, Karim S.; Dimopoulos, Meletios A.
(2018), Leuk Lymphoma, 59(6), 1364-1374
Mechanisms of receptor shedding in platelets
Montague, Samantha J.; Andrews, Robert K.; Gardiner, Elizabeth E.
(2018), Blood, 132(24), 2535-2545
Psammomys obesus
Chaudhary, Rajneesh; Walder, Ken R.; Hagemeyer, Christoph E.; Kanwar, Jagat R.
(2018), Curr Atheroscler Rep, 20(9), 46
Dimeric FcγR ectodomains detect pathogenic anti-platelet factor 4–heparin antibodies in heparin-induced thromobocytopenia
Wines, B. D.; Tan, C. W.; Duncan, E.; McRae, S.; Baker, R. I.; Andrews, R. K.; Esparon, S.; Gardiner, E. E.; Hogarth, P. M.
(2018), J Thromb Haemost, 16(12), 2520-2525
DOI: 10.1111/jth.14306
Daratumumab plus bortezomib and dexamethasone versus bortezomib and dexamethasone in relapsed or refractory multiple myeloma
Spencer, Andrew; Lentzsch, Suzanne; Weisel, Katja; Avet-Loiseau, Herv»; Mark, Tomer M.; Spicka, Ivan; Masszi, Tamas; Lauri, Birgitta; Levin, Mark David; Bosi, Alberto; Hungria, Vania; Cavo, Michele; Lee, Je Jung; Nooka, Ajay K.; Quach, Hang; Lee, Cindy; Barreto, Wolney; Corradini, Paolo; Min, Chang Ki; Scott, Emma C.; Chanan-Khan, Asher A.; Horvath, Noemi; Capra, Marcelo; Beksac, Meral; Ovilla, Roberto; Jo, Jae Cheol; Shin, Ho Jin; Sonneveld, Pieter; Soong, David; Casneuf, Tineke; Chiu, Christopher; Amin, Himal; Qi, Ming; Thiyagarajah, Piruntha; Sasser, A. Kate; Schecter, Jordan M.; Mateos, Maria Victoria
(2018), Haematologica, 103(12), 2079-2087
A phase 1 clinical trial evaluating marizomib, pomalidomide and low-dose dexamethasone in relapsed and refractory multiple myeloma (NPI-0052-107)
Spencer, Andrew; Harrison, Simon; Zonder, Jeffrey; Badros, Ashraf; Laubach, Jacob; Bergin, Krystal; Khot, Amit; Zimmerman, Todd; Chauhan, Dharminder; Levin, Nancy; MacLaren, Ann; Reich, Steven D.; Trikha, Mohit; Richardson, Paul
(2018), Br J Haematol, 180(1), 41-51
DOI: 10.1111/bjh.14987
Considerations for pre-transfusion immunohaematology testing in patients receiving the anti-CD38 monoclonal antibody daratumumab for the treatment of multiple myeloma
Quach, Hang; Benson, Simon; Haysom, Helen; Wilkes, Anne Marie; Zacher, Nicole; Cole-Sinclair, Merrole; Miles Prince, Henry; Mollee, Peter; Spencer, Andrew; Joy Ho, Phoebe; Harrison, Simon J.; Lee, Cindy; Augustson, Bradley; Daly, James
(2018), Intern Med J, 48(2), 210-220
DOI: 10.1111/imj.13707
NLRP3 regulates platelet integrin ±IIbβ3 outside-in signaling, hemostasis and arterial thrombosis
Qiao, Jianlin; Wu, Xiaoqing; Luo, Qi; Wei, Guangyu; Xu, Mengdi; Wu, Yulu; Liu, Yun; Li, Xiaoqian; Zi, Jie; Ju, Wen; Fu, Lin; Chen, Chong; Wu, Qingyun; Zhu, Shengyun; Qi, Kunming; Li, Depeng; Li, Zhenyu; Andrews, Robert K.; Zeng, Lingyu; Gardiner, Elizabeth E.; Xu, Kailin
(2018), Haematologica, 103(9), 1568-1576
Soluble GPVI is elevated in injured patients
Montague, Samantha J.; Delierneux, C»line; Lecut, Christelle; Layios, Nathalie; Dinsdale, Robert J.; Lee, Christine S.M.; Poulter, Natalie S.; Andrews, Robert K.; Hampson, Peter; Wearn, Christopher M.; Maes, Nathalie; Bishop, Jonathan; Bamford, Amy; Gardiner, Chris; Lee, Woei Ming; Iqbal, Tariq; Moiemen, Naiem; Watson, Steve P.; Oury, C»cile; Harrison, Paul; Gardiner, Elizabeth E.
(2018), Blood Adv, 2(3), 240-251
Characterization of Tfrc-mutant mice with microcytic phenotypes
Conway, Ashlee Jade; Brown, Fiona C.; Rank, Gerhard; Kile, Benjamin T.; Morton, Craig J.; Jane, Stephen M.; Curtis, David J.
(2018), Blood Adv, 2(5), 1914-1922
A novel role for Lyl1 in primitive erythropoiesis
Chiu, Sung Kai; Saw, Jesslyn Mei Yoong; Huang, Yizhou; Sonderegger, Stefan Eugen; Wong, Nicholas Chau Lun; Powell, David Richard; Beck, Dominic; Pimanda, John; Tremblay, Cedric; Curtis, David John
(2018), Development, 145(19), dev162990
DOI: 10.1242/dev.162990