Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Utility of circulating cell-free RNA analysis for the characterization of global transcriptome profiles of multiple myeloma patients

Chen, Maoshan; Mithraprabhu, Sridurga; Ramachandran, Malarmathy; Choi, Kawa; Khong, Tiffany; Spencer, Andrew

(2019), CANCERS, 11(6), 887

DOI: 10.3390/cancers11060887

Utility of a Nurse-Led Pathway for Patients with Acute Venous Thromboembolism Discharged on Rivaroxaban

Lim, Ming Sheng; Indran, Tishya; Cummins, Anita; Bennett, Ashwini; Wood, Erica; Brown, Susan; McQuilten, Zoe; Tran, Huyen; Chan, Noel C.; Chunilal, Sanjeev

(2019), SEMIN THROMB HEMOST, 45(2), 187-195.

DOI: 10.1055/s-0038-1676320

Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting Onto Iron Oxide Nanoparticles

Klein, Tobias; Parkin, Joshua; de Jongh, Patrick A.J.M.; Esser, Lars; Sepehrizadeh, Tara; Zheng, Gang; De Veer, Michael; Alt, Karen; Hagemeyer, Christoph E.; Haddleton, David M.; Davis, Thomas P.; Thelakkat, Mukundan; Kempe, Kristian

(2019), MACROMOL RAPID COMM, 40(10), 1800911

DOI: 10.1002/marc.201800911

Epigenetic treatment-mediated modulation of PD-L1 predicts potential therapy resistance over response markers in myeloid malignancies

Liu, Hongbin; Hu, Yunshan; Rimoldi, Rafael; Von Hagt, Chloe; Khong, Edmund W.C.; Lee, Nora; Flemming, Shaun; Spencer, Andrew; Dear, Anthony E.

(2019), ONCOL LETT, 17(2), 2543-2550.

DOI: 10.3892/ol.2018.9841

Exosomes Derived from Human Primary and Metastatic Colorectal Cancer Cells Contribute to Functional Heterogeneity of Activated Fibroblasts by Reprogramming Their Proteome

Rai, Alin; Greening, David W.; Chen, Maoshan; Xu, Rong; Ji, Hong; Simpson, Richard J.

(2019), PROTEOMICS, 19(8), 1800148

DOI: 10.1002/pmic.201800148

Combining BH3-Mimetics to target both BCL-2 and MCL1 has potent activity in pre-clinical models of acute myeloid leukemia

Moujalled, Donia M.; Pomilio, Giovanna; Ghiurau, Corina; Ivey, Adam; Salmon, Jessica; Rijal, Sewa; Macraild, Sarah; Zhang, Lan; Teh, Tse Chieh; Tiong, Ing Soo; Lan, Ping; Chanrion, Maia; Claperon, Audrey; Rocchetti, Francesca; Zichi, Adrien; Kraus-Berthier, Laurence; Wang, Youzhen; Halilovic, Ensar; Morris, Erick; Colland, Frédéric; Segal, David; Huang, David; Roberts, Andrew W.; Maragno, Ana Leticia; Lessene, Guillaume; Geneste, Olivier; Wei, Andrew H.

(2019), LEUKEMIA, 33(a), 905-917.

DOI: 10.1038/s41375-018-0261-3

Monitoring tumour burden and therapeutic response through analysis of circulating tumour DNA and extracellular RNA in multiple myeloma patients

Mithraprabhu, Sridurga; Morley, Rachel; Khong, Tiffany; Kalff, Anna; Bergin, Krystal; Hocking, Jay; Savvidou, Ioanna; Bowen, Kathryn M.; Ramachandran, Malarmathy; Choi, Kawa; Wong, Boris Ka Leong; Reynolds, John; Spencer, Andrew

(2019), LEUKEMIA, 33(8), 2022-2033.

DOI: 10.1038/s41375-019-0469-x

DNA-repair gene mutations are highly prevalent in circulating tumour dna from multiple myeloma patients

Mithraprabhu, Sridurga; Hocking, Jay; Ramachandran, Malarmathy; Choi, Kawa; Klarica, Daniela; Khong, Tiffany; Reynolds, John; Spencer, Andrew

(2019), CANCERS, 11(7), 917

DOI: 10.3390/cancers11070917

Autologous platelet-rich plasma for healing chronic venous leg ulcers

Weller, Carolina D.; Gardiner, Elizabeth E.; Arthur, Jane F.; Southey, Melissa; Andrews, Robert K.

(2019), INT WOUND J, 16(3), 788-792.

DOI: 10.1111/iwj.13098

Long-Term Motor Deficit and Diffuse Cortical Atrophy Following Focal Cortical Ischemia in Athymic Rats

Wang, Ting-Yi

(2019), FRONT CELL NEUROSCI, 13, 552

DOI: 10.3389/fncel.2019.00552

Tranexamic Acid Influences the Immune Response, but not Bacterial Clearance in a Model of Post-Traumatic Brain Injury Pneumonia

Draxler, Dominik F.; Awad, Milena M.; Hanafi, Gryselda; Daglas, Maria; Ho, Heidi; Keragala, Charithani; Galle, Adam; Roquilly, Antoine; Lyras, Dena; Sashindranath, Maithili; Medcalf, Robert L.

(2019), J NEUROTRAUM, 36(23), 3297-3308.

DOI: 10.1089/neu.2018.6030

KCC1 Activation protects Mice from the Development of Experimental Cerebral Malaria

Hortle, Elinor; Starrs, Lora; Brown, Fiona C.; Jane, Stephen M.; Curtis, David J.; McMorran, Brendan J.; Foote, Simon J.; Burgio, Gaetan

(2019), SCI REP-UK, 9(1), 6356

DOI: 10.1038/s41598-019-42782-x

Transcriptomic and proteomic analyses reveal new insights into the regulation of immune pathways during adenovirus type 2 infection

Zhao, Hongxing; Chen, Maoshan; Valdés, Alberto; Lind, Sara Bergström; Pettersson, Ulf

(2019), BMC MICROBIOL, 19(1), 1-17.

DOI: 10.1186/s12866-018-1375-5

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

Chopin, Michaël; Lun, Aaron T.; Zhan, Yifan; Schreuder, Jaring; Coughlan, Hannah; D'Amico, Angela; Mielke, Lisa A.; Almeida, Francisca F.; Kueh, Andrew J.; Dickins, Ross A.; Belz, Gabrielle T.; Naik, Shalin H.; Lew, Andrew M.; Bouillet, Phillipe; Herold, Marco J.; Smyth, Gordon K.; Corcoran, Lynn M.; Nutt, Stephen L.

(2019), IMMUNITY, 50(1), 77-90.e5.

DOI: 10.1016/j.immuni.2018.11.010

What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies

Picetti, Roberto; Shakur-Still, Haleema; Medcalf, Robert L.; Standing, Joseph F.; Roberts, Ian

(2019), BLOOD COAGUL FIBRIN, 30(1), 1-10.

DOI: 10.1097/MBC.0000000000000789

A review of global coagulation assays — Is there a role in thrombosis risk prediction?

Lim, Hui Yin; O'Malley, Cindy; Donnan, Geoffrey; Nandurkar, Harshal; Ho, Prahlad

(2019), THROMB RES, (179), 45-55.

DOI: 10.1016/j.thromres.2019.04.033

Genetic Variants Within the Erythroid Transcription Factor, KLF1, and Reduction of the Expression of Lutheran and Other Blood Group Antigens

Fraser, Nicole S.; Knauth, Christine M.; Moussa, Assia; Dean, Melinda M.; Hyland, Catherine A.; Perkins, Andrew C.; Flower, Robert L.; Schoeman, Elizna M.

(2019), TRANSFUS MED REV, 33(2), 111-117.

DOI: 10.1016/j.tmrv.2019.01.004

A comparison of the efficacy of immunomodulatory-free regimens in relapsed or refractory multiple myeloma

Weisel, Katja; Sonneveld, Pieter; Spencer, Andrew; Beksac, Meral; Rizzo, Maria; Xu, Yingxin; Fahrbach, Kyle; Gaudig, Maren; Slavcev, Mary; Dearden, Lindsay; Lam, Annette

(2019), LEUKEMIA LYMPHOMA, 60(19), 151–162.

DOI: 10.1080/10428194.2018.1466392

The NUP98-HOXD13 fusion oncogene induces thymocyte self-renewal via Lmo2/Lyl1

Shields, Benjamin J.; Slape, Christopher I.; Vo, Ngoc; Jackson, Jacob T.; Pliego-Zamora, Adriana; Ranasinghe, Hansini; Shi, Wei; Curtis, David J.; McCormack, Matthew P.

(2019), LEUKEMIA, 33(8), 1868-1880

DOI: 10.1038/s41375-018-0361-0

Renal impairment at diagnosis in myeloma: Patient Characteristics, Treatment, and Impact on Outcomes. Results From the Australia and New Zealand Myeloma and Related Diseases Registry

Ho, P. Joy; Moore, Elizabeth M.; McQuilten, Zoe K.; Wellard, Cameron; Bergin, Krystal; Augustson, Bradley; Blacklock, Hilary; Harrison, Simon J.; Horvath, Noemi; King, Tracy; Mollee, Peter; Quach, Hang; Reid, Christopher; Rosengarten, Brian; Walker, Patricia; Wood, Erica M.; Spencer, Andrew

(2019), CL LYMPH MYELOM LEUK, 19(8), E415-E424.

DOI: 10.1016/j.clml.2019.05.010