Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Acute myeloid leukemia maturation lineage influences residual disease and relapse following differentiation therapy

Ngo, Steven; Oxley, Ethan P.; Ghisi, Margherita; Garwood, Maximilian M.; McKenzie, Mark D.; Mitchell, Helen L.; Kanellakis, Peter; Susanto, Olivia; Hickey, Michael J.; Perkins, Andrew C.; Kile, Benjamin T.; Dickins, Ross A.

(2021), NAT COMMUN, 12(1), 6546

DOI: 10.1038/s41467-021-26849-w

Cerebral Amyloid Angiopathy and the Fibrinolytic System

Mutimer, Chloe A.; Keragala, Charithani B.; Markus, Hugh S.; Werring, David J.; Cloud, Geoffrey C.; Medcalf, Robert L.

(2021), STROKE, 52(8), 2707-2714

DOI: 10.1161/STROKEAHA.120.033107

Correction

Mithraprabhu, Sridurga; Chen, Maoshan; Savvidou, Ioanna; Reale, Antonia; Spencer, Andrew

(2021), LEUKEMIA, 35(10), 3037

DOI: 10.1038/s41375-021-01399-8

Liquid biopsy: an evolving paradigm for the biological characterisation of plasma cell disorders

Mithraprabhu, Sridurga; Chen, Maoshan; Savvidou, Ioanna; Reale, Antonia; Spencer, Andrew

(2021), LEUKEMIA, 35(10), 2771-2783

DOI: 10.1038/s41375-021-01339-6

Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues

Millard, Susan M.; Heng, Ostyn; Opperman, Khatora S.; Sehgal, Anuj; Irvine, Katharine M.; Kaur, Simranpreet; Sandrock, Cheyenne J.; Wu, Andy C.; Magor, Graham W.; Batoon, Lena; Perkins, Andrew C.; Noll, Jacqueline E.; Zannettino, Andrew C.W.; Sester, Davi

(2021), CELL REP, 37(8), 110058

DOI: 10.1016/j.celrep.2021.110058

Two Weeks of Low Molecular Weight Heparin for Isolated Symptomatic Distal Vein Thrombosis (TWISTER study)

Merriman, Eileen; Chunilal, Sanjeev; Brighton, Tim; Chen, Vivien; McRae, Simon; Ockelford, Paul; Curnow, Jennifer; Tran, Huy; Chong, Beng; Smith, Mark; Royle, Gordon; Crowther, Helen; Slocombe, Alison; Tran, Huyen

(2021), THROMB RES, 207, 33-39

DOI: 10.1016/j.thromres.2021.09.004

Fibrinolysis: A Primordial System Linked to the Immune Response

Medcalf, Robert L.; Keragala, Charithani B.

(2021), INT J MOL SCI, 22(7), 3406

DOI: 10.3390/ijms22073406

The Fibrinolytic System: Mysteries and Opportunities

Medcalf, Robert L.; Keragala, Charithani B.

(2021), HemaSphere, 5(6), e570

DOI: 10.1097/HS9.0000000000000570

Platelet phenotype and function in the absence of splenic sequestration (Review)

Luu, Sarah; Woolley, Ian J.; Andrews, Robert K.

(2021), PLATELETS, 32(1), 48-53

DOI: 10.1080/09537104.2020.1732322

Global coagulation assays in healthy controls

Lim, Hui Yin; Lui, Brandon; Tacey, Mark; Selan, Carly; Donnan, Geoffrey; Burrell, Louise M.; Nandurkar, Harshal; Ho, Prahlad

(2021), J THROMB THROMBOLYS, 52(2), 610–619

DOI: 10.1007/s11239-021-02400-y

Global coagulation assays in patients with diabetes mellitus

Lim, Hui Yin; Lui, Brandon; Tacey, Mark; Kwok, Anna; Varadarajan, Suresh; Donnan, Geoffrey; Nandurkar, Harshal; Ho, Prahlad

(2021), Research and Practice in Thrombosis and Haemostasis, 5(7), e12611

DOI: 10.1002/rth2.12611

Determination of PAR4 numbers on the surface of human platelets

Li, Simeng; Tarlac, Volga; Christanto, Roberto B.I.; French, Shauna L.; Hamilton, Justin R.

(2021), PLATELETS, 32(7), 988-991

DOI: 10.1080/09537104.2020.1810654

Role of purinergic signalling in endothelial dysfunction and thrombo-inflammation in ischaemic stroke and cerebral small vessel disease

Lee, Natasha Ting; Ong, Lin Kooi; Gyawali, Prajwal; Nassir, Che Mohd Nasril Che Mohd; Mustapha, Muzaimi; Nandurkar, Harshal H.; Sashindranath, Maithili

(2021), BIOMOLECULES, 11(7), 994

DOI: 10.3390/biom11070994

Effects of water stably-enriched with oxygen as a novel method of tissue oxygenation on mitochondrial function, and as adjuvant therapy for type 2 diabetes in a randomized placebo-controlled trial

Khoo, Joan; Hagemeyer, Christoph; Henstridge, Darren C.; Kumble, Sumukh; Wang, Ting-Yi; Xu, Rong; Gani, Linsey; King, Thomas; Soh, Shui-Boon; Puar, Troy; Au, Vanessa; Tan, Eberta; Tay, Tunn Lin; Kam, Carmen; Teo, Eng-Kiong

(2021), PLOS ONE, 16(7), e0254619

DOI: 10.1371/journal.pone.0254619

Plasminogen: an enigmatic zymogen

Keragala, Charithani B.; Medcalf, Robert L.

(2021), BLOOD, 137(21), 2881-2889

DOI: 10.1182/blood.2020008951

Broad-based influenza-specific cd8+ t cell response without the typical immunodominance hierarchy and its potential implication

Huang, Miaojuan; Xu, Rong; Triffon, Cristina; Mifsud, Nicole; Chen, Weisan

(2021), VIRUSES-BASEL, 13(6), 1080

DOI: 10.3390/v13061080

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

Hogg, Simon J.; Motorna, Olga; Cluse, Leonie A.; Johanson, Timothy M.; Coughlan, Hannah D.; Raviram, Ramya; Myers, Robert M.; Costacurta, Matteo; Todorovski, Izabela; Pijpers, Lizzy; Bjelosevic, Stefan; Williams, Tobias; Huskins, Shannon N.; Kearney, Cono

(2021), MOL CELL, 81(10), 2183-2200e13

DOI: 10.1016/j.molcel.2021.04.015

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro

Hoefer, Thomas; Rana, Akshita; Niego, Be'eri; Jagdale, Shweta; Albers, Hugo J.; Gardiner, Elizabeth E.; Andrews, Robert K.; van der Meer, Andries D.; Hagemeyer, Christoph e.; Westein, Erik

(2021), HAEMATOLOGICA, 106(11), 2874-2884

DOI: 10.3324/haematol.2020.250761

Chronic methamphetamine interacts with BDNF Val66Met to remodel psychosis pathways in the mesocorticolimbic proteome

Greening, David W.; Notaras, Michael; Chen, Maoshan; Xu, Rong; Smith, Joel D.; Cheng, Lesley; Simpson, Richard J.; Hill, Andrew F.; van den Buuse, Maarten

(2021), MOL PSYCHIATR, 26(8), 4431-4447

DOI: 10.1038/s41380-019-0617-8

Deletion of IKK2 in haematopoietic cells of adult mice leads to elevated interleukin-6, neutrophilia and fatal gastrointestinal inflammation

Fischer, Karla C.; Daunt, Carmel P.; Tremblay, Cédric S.; Dias, Sheila; Vince, James E.; Jabbour, Anissa M.

(2021), CELL DEATH DIS, 12(1), 28

DOI: 10.1038/s41419-020-03298-9

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