Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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EPO does not promote interaction between the erythropoietin and beta-common receptors

Cheung Tung Shing, Karen S.; Broughton, Sophie E.; Nero, Tracy L.; Gillinder, Kevin; Ilsley, Melissa D.; Ramshaw, Hayley; Lopez, Angel F.; Griffin, Michael D.W.; Parker, Michael W.; Perkins, Andrew C.; Dhagat, Urmi

(2018), Sci Rep, 8(1), 12457

DOI: 10.1038/s41598-018-29865-x

Understanding of the significance and health implications of asplenia in a cohort of patients with haemaglobinopathy

Premawardena, Chamath; Bowden, Donald; Kaplan, Zane; Dendle, Claire; Woolley, Ian John

(2018), Hematology, 23(8), 526-530

DOI: 10.1080/10245332.2017.1414910

Haemostasis and innate immunity – a complementary relationship

Keragala, Charithani B.; Draxler, Dominik F.; McQuilten, Zoe K.; Medcalf, Robert L.

(2018), Br J Haematol, 180(6), 782-798

DOI: 10.1111/bjh.15062

Current and future antiplatelet therapies

McFadyen, James D.; Schaff, Mathieu; Peter, Karlheinz

(2018), Nat Rev Cardiol, 15(3), 181-191

DOI: 10.1038/nrcardio.2017.206

Elastomeric microvalve geometry affects haemocompatibility

Szydzik, Crispin; Brazilek, Rose J.; Khoshmanesh, Khashayar; Akbaridoust, Farzan; Knoerzer, Markus; Thurgood, Peter; Muir, Ineke; Marusic, Ivan; Nandurkar, Harshal; Mitchell, Arnan; Nesbitt, Warwick S.

(2018), Lab Chip, 18(12), 1778-1792

DOI: 10.1039/c7lc01320e

Direct Oral Anticoagulants and the Paradigm Shift in the Management of Venous Thromboembolism

Lim, Hui Yin; Nandurkar, Harshal; Ho, Prahlad

(2018), Semin Thromb Hemost, 44(3), 261-266

DOI: 10.1055/s-0038-1637750

Hhex induces promyelocyte self-renewal and cooperates with growth factor independence to cause myeloid leukemia in mice

Jackson, Jacob Tony; Ng, Ashley; Shields, Benjamin James; Haupt, Sue Moody; Haupt, Ygal; McCormack, Matthew Paul

(2018), Blood Adv, 2(4), 347-360

DOI: 10.1182/bloodadvances.2017013243

Investigation of the variable In(Lu) phenotype caused by KLF1 variants

Fraser, Nicole S.; Knauth, Christine M.; Schoeman, Elizna M.; Moussa, Assia; Perkins, Andrew C.; Walsh, Terry; Millard, Glenda M.; Dean, Melinda M.; Hyland, Catherine A.; Flower, Robert L.

(2018), Transfusion, 58(10), 2414-2420

DOI: 10.1111/trf.14926

Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency

Conway, Ashlee; Brown, Fiona C; Hortle, Elinor J.; Burgio, Gaetan; Foote, Simon J; Morton, Craig James; Jane, Stephen M.; Curtis, David J.

(2018), Dis Model Mech, 11(5),

DOI: 10.1242/dmm.034678

Low-Fouling and Biodegradable Protein-Based Particles for Thrombus Imaging

Bonnard, Thomas; Jayapadman, Anand; Putri, Jasmine A.; Cui, Jiwei; Ju, Yi; Carmichael, Catherine; Angelovich, Thomas A.; Cody, Stephen H.; French, Shauna; Pascaud, Karline; Pearce, Hannah A.; Jagdale, Shweta; Caruso, Frank; Hagemeyer, Christoph E.

(2018), ACS Nano, 12(7), 6988-6996

DOI: 10.1021/acsnano.8b02588

Self-Assembled Metal–Phenolic Networks on Emulsions as Low-Fouling and pH-Responsive Particles

Besford, Quinn A.; Ju, Yi; Wang, Ting Yi; Yun, Gyeongwon; Cherepanov, Pavel V.; Hagemeyer, Christoph E.; Cavalieri, Francesca; Caruso, Frank

(2018), Small, 14(39), 1802342

DOI: 10.1002/smll.201802342

Mining the plasma cell transcriptome for novel cell surface proteins

Trezise, Stephanie; Karnowski, Alexander; Fedele, Pasquale L.; Mithraprabhu, Sridurga; Liao, Yang; D’costa, Kathy; Kueh, Andrew J.; Hardy, Matthew P.; Owczarek, Catherine M.; Herold, Marco J.; Spencer, Andrew; Shi, Wei; Willis, Simon N.; Nutt, Stephen L.; Corcoran, Lynn M.

(2018), Int J Mol Sci, 19(8), 2161

DOI: 10.3390/ijms19082161

Mutant KLF1 in Adult Anemic Nan Mice Leads to Profound Transcriptome Changes and Disordered Erythropoiesis

N»bor, Danitza; Graber, Joel H.; Ciciotte, Steven L.; Robledo, Raymond F.; Papoin, Julien; Hartman, Emily; Gillinder, Kevin R.; Perkins, Andrew C.; Bieker, James J.; Blanc, Lionel; Peters, Luanne L.

(2018), Sci Rep, 8(1), 12793

DOI: 10.1038/s41598-018-30839-2

Intravital Imaging to Monitor Therapeutic Response in Moving Hypoxic Regions Resistant to PI3K Pathway Targeting in Pancreatic Cancer

Conway, James R.W.; Warren, Sean C.; Herrmann, David; Murphy, Kendelle J.; Cazet, Aur»lie S.; Vennin, Claire; Shearer, Robert F.; Killen, Monica J.; Magenau, Astrid; M»l»nec, Pauline; Pinese, Mark; Nobis, Max; Zaratzian, Anaiis; Boulghourjian, Alice; Da Silva, Andrew M.; del Monte-Nieto, Gonzalo; Adam, Arne S.A.; Harvey, Richard P.; Haigh, Jody J.; Wang, Yingxiao; Croucher, David R.; Sansom, Owen J.; Pajic, Marina; Caldon, C. Elizabeth; Morton, Jennifer P.; Timpson, Paul

(2018), Cell Rep, 23(11), 3312-3326

DOI: 10.1016/j.celrep.2018.05.038

Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity

Tremblay, C»dric S.; Huang, Feng Fei; L»vesque, Georges; Carreau, Madeleine

(2018), BMC Res Notes, 11(1), 138

DOI: 10.1186/s13104-018-3243-7

Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis

Goldie, Stephen J.; Cottle, Denny L.; Tan, Fiona H.; Roslan, Suraya; Srivastava, Seema; Brady, Rhys; Partridge, Darren D.; Auden, Alana; Smyth, Ian M.; Jane, Stephen M.; Dworkin, Sebastian; Darido, Charbel

(2018), Cell Death Dis, 9(11), 1072

DOI: 10.1038/s41419-018-0901-6

Development of chondrocyte-seeded electrosprayed nanoparticles for repair of articular cartilage defects in rabbits

Yang, Shan Wei; Ku, Kai Chi; Chen, Shu Ying; Kuo, Shyh Ming; Chen, I. Fen; Wang, Ting Yi; Chang, Shwu Jen

(2018), J BIOMATER APPL, 32(6), 800-812

DOI: 10.1177/0885328217740729

A single-chain antibody-CD39 fusion protein targeting activated platelets protects from cardiac ischaemia/reperfusion injury

Ziegler, M., Hohmann, J.D., Searle, A.K., Abraham, M.-K., Nandurkar, H.H., Wang, X., Peter, K.

(2018), Eur Heart J, 111-116

DOI: 10.1093/eurheartj/ehx218

CD39 and CD73 activity are protective in a mouse model of antiphospholipid antibody-induced miscarriages

Samudra, A.N., Dwyer, K.M., Selan, C., Freddi, S., Murray-Segal, L., Nikpour, M., Hickey, M.J., Peter, K., Robson, S.C., Sashindranath, M., Cowan, P.J., Nandurkar, H.H.

(2018), J Autoimmun, 131-138

DOI: 10.1016/j.jaut.2017.10.009

Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome

Kraakman, M.J., Kammoun, H.L., Dragoljevic, D., Al-Sharea, A., Lee, M.K.S., Flynn, M.C., Stolz, C.J., Guirguis, A.A., Lancaster, G.I., Chin-Dusting, J., Curtis, D.J., Murphy, A.J.

(2018), Haematologica, 597-606

DOI: 10.3324/haematol.2017.181958

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