Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling

Furtado MB, Wilmanns JC, Chandran A, Perera J, Hon O, Biben C, Willow TJ, Nim HT, Kaur G, Simonds S, Wu Q, Willians D, Salimova E, Plachta N, Denegre JM, Murray SA, Fatkin D, Cowley M, Pearson JT, Kaye D, Ramialison M, Harvey RP, Rosenthal NA, Costa MW

(2017), JCI Insight, 2(6), e88271

DOI: 10.1172/jci.insight.88271

Atrial fibrillation and heart failure - cause or effect?

Prabhu S, Voskoboinik A, Kaye DM, Kistler PM

(2017), Heart Lung Circ, 26(9), 967-74

DOI: 10.1016/j.hlc.2017.05.117

Catheter ablation versus medical rate control in atrial fibrillation and systolic dysfunction: the CAMERA-MRI study

Prabhu S, Taylor AJ, Costello BT, Kaye DM, McLellan AA, Voskoboinik A, Sugumar H, Lockwood SM, Stokes MB, Pathik B, Nalliah CJ, Wong GR, Azzopardi SM, Gutman S, Lee G, Layland J, Mariani JA, Ling LH, Kalman JM, Kistler PM

(2017), J Am Coll Cardiol, 70(16), 1949-61

DOI: 10.1016/j.jacc.2017.08.041

Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction

Kaye DM, Silvestry FE, Gustafsson F, Cleland JG, van Veldhuisen DJ, Ponikowski P, Komtebedde J, Nanayakkara S, Burkhoff D, Shah SJ

(2017), Eur J Heart Fail, 19(12), 1690-7

DOI: 10.1002/ejhf.930

A randomized double-blind trial of an interventional device treatment of functional mitral regurgitation in patients with symptomatic congestive heart failure-Trial design of the REDUCE FMR study

Goldberg SL, Meredith I, Marwick T, Haluska BA, Lipiecki J, Siminiak T, Mehta N, Kaye DM, Sievert H; REDUCE FMR Investigators

(2017), Am Heart J, 188, 167-74

DOI: 10.1016/j.ahj.2017.02.032

Hemodynamic profile of patients with heart failure and preserved ejection fraction vary by age

Nanayakkara S, Haykowsky M, Mariani J, Van Empel V, Maeder MT, Vizi D, Kaye DM

(2017), J Am Heart Assoc, 6(9), e005434

DOI: 10.1161/JAHA.116.005434

Extended release oral milrinone as an adjunct to heart failure therapy

Nanayakkara S, Bergin P, Mak V, Crannitch K, Kaye D

(2017), Intern Med J, 47(8), 973-4

DOI: 10.1111/imj.13503

Emerging therapies for heart failure with preserved ejection fraction

Nanayakkara S, Mariani J, Kaye D

(2017), Cardiol Today, 7, 26-8

Targets for heart failure with preserved ejection fraction

Nanayakkara S, Kaye DM

(2017), Clin Pharmacol Ther, 102, 228-37

DOI: 10.1002/cpt.723

Heart failure with preserved ejection fraction: improving diagnosis and management

Nanayakkara S, Mariani J, Kaye D

(2017), Med Today, 18(1), 37-42

Exercise hemodynamics as a predictor of myocardial recovery in LVAD patients

Segan L, Nanayakkara S, Leet A, Vizi D, Kaye DM

(2017), ASAIO J, 63(3), 342-5

DOI: 10.1097/MAT.0000000000000490

Late presentation of right atrial thrombus following bilateral lung transplant

Saxena P, Nerlekar N, Zimmet AD

(2017), Asian Cardiovasc Thorac Ann, 25(1), 65-6

DOI: 10.1177/0218492315623433

Targeting activated platelets: a unique and potentially universal approach for cancer imaging

Yap ML, McFadyen JD, Wang X, Zia NA, Hohmann JD, Ziegler M, Yao Y, Pham A, Harris M, Donnelly PS, Hogarth PM, Pietersz GA, Lim B, Peter K

(2017), Theranostics, 7(10), 2565-74

DOI: 10.7150/thno.19900

Cardiac magnetic resonance imaging in suspected blunt cardiac injury: a prospective, pilot, cohort study

Burrell AJ, Kaye DM, Fitzgerald MC, Cooper DJ, Hare JL, Costello BT, Taylor AJ

(2017), Injury, 48, 1013-9

DOI: 10.1016/j.injury.2017.02.025

Changing target temperature from 33°C to 36°C in the ICU management of out-of-hospital cardiac arrest: a before and after study

Bray JE, Stub D, Bloom JE, Segan L, Mitra B, Smith K, Finn J, Bernard S

(2017), Resuscitation, 113, 39-43

DOI: 10.1016/j.resuscitation.2017.01.016

Is early rehabilitation a myth? Physical inactivity in the first week after myocardial infarction and stroke

Lay S, Bernhardt J, West T, Churilov L, Dart A, Hayes K, Cumming TB

(2016), Disabil Rehabil, 38(15),

Impact of door-to-balloon time on long-term mortality in high- and low-risk patients with ST-elevation myocardial infarction

Yudi MB, Ramchand J, Farouque O, Andrianopoulos N, Chan W, Duffy SJ, Lefkovits J, Brennan A, Spencer R, Fernando D, Hiew C, Freeman M, Reid CM, Ajani AE, Clark DJ; Melbourne Interventional Group

(2016), Int J Cardiol, 224,

Clopidogrel, prasugrel or ticagrelor in patients with acute coronary syndromes undergoing percutaneous coronary intervention

Yudi MB, Clark DJ, Farouque O, Eccleston D, Andrianopoulos N, Duffy SJ, Brennan A, Lefkovits J, Ramchand J, Yip T, Oqueli E, Reid CM, Ajani AE; Melbourne Interventional Group

(2016), Intern Med J, 46(5),

Early versus delayed percutaneous coronary intervention in patients with non-ST elevation acute coronary syndromes

Yudi MB, Ajani AE, Andrianopoulos N, Duffy SJ, Farouque O, Ramchand J, Gurvitch R, Lefkovits J, Freeman M, Brennan A, Clark DJ, Reid C, Eccleston D; Melbourne Interventional Group

(2016), Coron Artery Dis, 27(5),

Incidence, predictors and outcomes of major bleeding in patients following percutaneous coronary interventions in Australia

Wlodarczyk J, Ajani AE, Kemp D, Andrianopoulos N, Brennan AL, Duffy SJ, Clark DJ, Reid CM

(2016), Heart Lung Circ, 25(2),

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