Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection (GEMINI-1 and GEMINI-2)

Cahn, Pedro; Madero, Juan Sierra; Arribas, José Ramón; Antinori, Andrea; Ortiz, Roberto; Clarke, Amanda E.; Hung, Chien Ching; Rockstroh, Jürgen K.; Girard, Pierre Marie; Sievers, Jörg; Man, Choy; Currie, Alexander; Underwood, Mark; Tenorio, Allan R.; Pappa, Keith; Wynne, Brian; Fettiplace, Anna; Gartland, Martin; Aboud, Michael; Smith, Kimberly; Cassetti, Lidia; David, Daniel; Figueras, Laura; Losso, Marcelo; Lopardo, Gustavo; Lupo, Sergio; Porteiro, Norma; Sánchez, Marisa; Bloch, Mark; Cooper, David; Finlayson, Robert; Kelleher, Anthony; Koh, Kenneth; Lewis, David; McMahon, James; Moore, Richard; Roth, Norman; Shields, Matthew; De Wit, Stephane; Florence, Eric; Goffard, Jean Christophe; Demeester, Remy; Lacor, Patrick; Vandercam, Bernard; Vandekerckhove, Linos; Angel, Jonathan; Baril, Jean Guy; Conway, Brian; De Pokomandy, Alexandra; Szabo, Jason; Walmsley, Sharon; Bouchaud, Olivier; Chidiac, Christian; Delobel, Pierre; Goujard, Cecile; Katlama, Christine; Molina, Jean Michel; Pialoux, Gilles; Philibert, Patrick; Bogner, Johannes; Esser, Stefan; Krznaric, Ivanka; Lehmann, Clara; Spinner, Christoph; Stellbrink, Hans Jurgen; Stephan, Christoph; Stoehr, Albrecht; Barchi, Enrico; Caramello, Pietro; Castelli, Francesco; Cattelan, Anna Maria; D'Arminio Monforte, Antonella; Di Biagio, Antonio; Di Perri, Giovanni; Gori, Andrea; Maggiolo, Franco; Menzaghi, Barbara; Migliorino, Guglielmo; Mussini, Cristina; Penco, Giovanni; Puoti, Massimo; Rizzardini, Giuliano; Gulminetti, Roberto; Lazzarin, Adriano; Quirino, Tiziano; Sighinolfi, Laura; Viale, Pierluigi; Amaya Tapia, Gerardo; Andrade Villanueva, Jaime; Granados Reyes, Enrique R.; Perez Rios, Alma; Santoscoy Gomez, Mario; Den Hollander, Jan; Rijnders, Bart; Hidalgo, José A.; Hercilla Vasquez, Luis; Illescas, Luis; Olczak, Anita; Mansinho, Kamal; Correia Pacheco, Patricia Paula; Teófilo, Eugénio; Saraiva da Cunha, Jose; Sarmento e Castro, Rui; Serrão, Rosário; Arbune, Manuela; Jianu, Cristian; Oprea, Anca; Preotescu, Liliana; Prisacariu, Liviu Jany; Belonosova, Elena; Borodkina, Olga; Chernova, Oxana; Gankina, Natalia; Kizhlo, Svetlana; Kulagin, Valeriy; Kurina, Nadezhda; Nagimova, Firaya; Pokrovsky, Vadim; Ryamova, Elena; Voronin, Evgeny; Yakovlev, Alexey; Kaplan, Richard; Lee, Sun Hee; Kim, Shin Woo; Kim, Sang Il; Kim, Woo Joo; Antela Lopez, Antonio; Casado Osorio, Jose L.; Castaño Carracedo, Manuel A.; De Los Santos Gil, Ignacio; Estrada Perez, Vicente; Falco Ferrer, Vicenç; Force, Luis; Galinda Puerto, Maria Jose; Garcia Deltoro, Miguel; Gatell, Josep M.; Goenaga Sanchez, Miguel A.; González Cordón, Ana; Knobel, Hernando; Lopez Bernaldo de Quiros, Juan Carlos; Losa Garcia, Juan E.; Masia, Mar; Montero-Alsonso, Marta; Ocampo Hermida, Antonio; Pasquau Liaño, Juan; Portilla Sogorb, Joaquin; Pulido Ortega, Federico; Rivera Roman, Antonio; Santos Fernandez, Jose Ramon; Torres Perea, Rafael; Troya Garcia, Jesus; Viciana Fernandez, Pompeyo; Calmy, Alexandra; Hauser, Christoph; Fehr, Jan; Cheng, Shu Hsing; Ko, Wen Chien; Lin, Hsi Hsun; Lu, Po Liang; Tseng, Yu Ting; Wang, Ning Chi; Wong, Wing Wai; Yang, Chia Jui; Arduino, Roberto; Benson, Paul; Berhe, Mezgebe; Bredeek, Fritz; Brinson, Cynthia; Campbell, Thomas; Crofoot, Gordon; Cunningham, Douglas; DeJesus, Edwin; Dretler, Robin; Eron, Joseph; Fife, Kenneth; Fichtenbaum, Carl; Flamm, Jason; Goldstein, Deborah; Gupta, Samir; Hagins, Debbie; Hoffman-Terry, Margaret; Jayaweera, Dushyantha; Kinder, Clifford; Klein, Daniel; McDonald, Cheryl; Mills, Anthony; Nahass, Ronald; Osiyemi, Olayemi; Overton, Edgar; Parks, David; Prelutsky, David; Ramgopal, Moti; Schrader, Shannon; Sha, Beverly; Simon, Gary; Sims, James; Skiest, Daniel; Slim, Jihad; Tashima, Karen; Thedinger, Blair; Gazzard, Brian; Fox, Julie; Johnson, Margaret; Kegg, Stephen; Khoo, Saye; Mazhude, Charles; Orkin, Chloe; Schembri, Gabriel; Ustianowski, Andrew; ,

(2019), LANCET, 393(10167), 143-155.

DOI: 10.1016/S0140-6736(18)32462-0

Colonizing multidrug-resistant bacteria and the longitudinal evolution of the intestinal microbiome after liver transplantation

Annavajhala, Medini K.; Gomez-Simmonds, Angela; Macesic, Nenad; Sullivan, Sean B.; Kress, Anna; Khan, Sabrina D.; Giddins, Marla J.; Stump, Stephania; Kim, Grace I.; Narain, Ryan; Verna, Elizabeth C.; Uhlemann, Anne-Catrin

(2019), NAT COMMUN, 10(1), 4715

DOI: 10.1038/s41467-019-12633-4

Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome Is Associated With Dysregulation of IL-7/IL-7 Receptor Signaling Pathway in T Cells and Monocyte Activation

Akilimali, Ngomu Akeem; Muema, Daniel M.; Specht, Charles; Chang, Christina C.; Moosa, Mahomed Yunus S.; Levitz, Stuart M.; Lewin, Sharon R.; French, Martyn A.; Ndungʼu, Thumbi

(2019), JAIDS-J ACQ IMM DEF, 80(5), 596-604.

DOI: 10.1097/QAI.0000000000001946

Spectrum of illness among returned Australian travellers from Bali, Indonesia

Sohail, Asma; McGuinness, Sarah L.; Lightowler, Rachel; Leder, Karin; Jomon, Bismi; Bain, Christopher A.; Peleg, Anton Y.

(2019), INTERN MED J, 49(1), 34-40.

DOI: 10.1111/imj.13993

The World Association against Infection in Orthopaedics and Trauma (WAIOT) procedures for Microbiological Sampling and Processing for Periprosthetic Joint Infections (PJIs) and other Implant-Related Infections

Drago, Lorenzo; Clerici, Pierangelo; Morelli, Ilaria; Ashok, Johari; Benzakour, Thami; Bozhkova, Svetlana; Alizadeh, Chingiz; del Sel, Hernán; Sharma, Hemant K; Peel, Trisha; Mattina, Roberto; Romanò, Carlo Luca

(2019), J CLIN MED, 8(7), 933

DOI: 10.3390/jcm8070933

A national study of the clinical management of HIV-positive women in Australia:What are the successes and where are the gaps?

Giles, Michelle L.; Macphail, Aleece; Bell, Charlotte; Bradshaw, Catriona S.; Furner, Virginia; Gunathilake, Manoji; John, Mina; Krishnaswamy, Sushena; Martin, Sarah J.; Ooi, Catriona; Owen, Louise; Russell, Darren; Street, Alan; Post, Jeffrey J.

(2019), SEX HEALTH, 16(3), 282-288.

DOI: 10.1071/SH18070

Association between plasma antibody responses and risk for Cryptococcus-associated immune reconstitution inflammatory syndrome

Yoon, Hyun Ah; Nakouzi, Antonio; Chang, Christina C.; Kuniholm, Mark; Carreño, Leandro J.; Wang, Tao; Ndung'u, Thumbi; Lewin, Sharon Ruth; French, Martyn A; Pirofski, Liise-Anne

(2019), J INFECT DIS, 219(3), 420-428.

DOI: 10.1093/infdis/jiy447

CD4- and time-dependent susceptibility of HIV-1-infected cells to antibody-dependent cellular cytotoxicity

Lee, Wen Shi; Prévost, Jérémie; Richard, Jonathan; van der Sluis, Reneé M.; Lewin, Sharon R.; Pazgier, Marzena; Finzi, Andrés; Parsons, Matthew S.; Kent, Stephen J.

(2019), J VIROL, 93(10, e01901-18.

DOI: 10.1128/JVI.01901-18

Recruiting people with HIV to an online self-management support randomised controlled trial

Klassen, Karen M.; Millard, Tanya; Stout, Julia; McDonald, Karalyn; Dodson, Sarity; Osborne, Richard H.; Battersby, Malcolm W.; Fairley, Christopher K.; Kidd, Michael R.; McMahon, James; Baker, David; Elliott, Julian H.

(2019), SEX HEALTH, 16(4), 340-347.

DOI: 10.1071/SH18130

Modulation of the CCR5 Receptor/Ligand Axis by Seminal Plasma and the Utility of in Vitro versus in Vivo Models

Juno, Jennifer A.; Wragg, Kathleen M.; Kristensen, Anne B.; Lee, Wen Shi; Selva, Kevin J.; Van Der Sluis, Renee M.; Kelleher, Anthony D.; Bavinton, Benjamin R.; Grulich, Andrew E.; Lewin, Sharon R.; Kent, Stephen J.; Parsons, Matthew S.

(2019), J VIROL, 93(11), e0024219.

DOI: 10.1128/JVI.00242-19

Closing the gap in surveillance and audit of invasive mold diseases for antifungal stewardship using machine learning

Baggio, Diva; Peel, Trisha; Peleg, Anton Y.; Avery, Sharon; Prayaga, Madhurima; Foo, Michelle; Haffari, Reza; Liu, Ming; Bergmeir, Christoph; Ananda-Rajah, Michelle

(2019), J CLIN MED, 8(9), 1390

DOI: 10.3390/jcm8091390

Population Pharmacokinetics and Pharmacodynamics of Disulfiram on Inducing Latent HIV-1 Transcription in a Phase IIb Trial

Lee, Sulggi A.; Elliott, Julian H.; McMahon, James; Hartogenesis, Wendy; Bumpus, Namandje N.; Lifson, Jeffrey D.; Gorelick, Robert J.; Bacchetti, Peter; Deeks, Steven G.; Lewin, Sharon R.; Savic, Radojka M.

(2019), CLIN PHARMACOL THER, 105(3), 692-702.

DOI: 10.1002/cpt.1220

Oxacillin Coupled G-Quadruplexes as a Novel Biofilm-Specific Antibiotic for Staphylococcus aureus Biofilms

Fenati, Renzo A.; Locock, Katherine; Qu, Yue; Ellis, Amanda V.

(2019), ACS Appl Bio Mater, 2(7), 3002-3008.

DOI: 10.1021/acsabm.9b00336

The impact of sample storage on molecular-based detection of Mycoplasma genitalium

Murray, G. L.; Su, J. P.; Birnie, J.; Danielewski, J.; Machalek, D. A.; Bradshaw, C. S.; Read, T. R.H.; Costa, A. M.; Garland, S. M.

(2019), J APPL MICROBIOL, 127(4), 1219-1223.

DOI: 10.1111/jam.14359

Identification of Novel Acinetobacter baumannii Host Fatty Acid Stress Adaptation Strategies

Jiang, Jhih Hang; Hassan, Karl A.; Begg, Stephanie L.; Rupasinghe, Thusitha W.T.; Naidu, Varsha; Pederick, Victoria G.; Khorvash, Marjan; Whittall, Jonathan J.; Paton, James C.; Paulsen, Ian T.; McDevitt, Christopher A.; Peleg, Anton Y.; Eijkelkamp, Bart A.

(2019), MBIO, 10(1), e02056-18.

DOI: 10.1128/mBio.02056-18

A population-based analysis of invasive fungal disease in haematology-oncology patients using data linkage of state-wide registries and administrative databases

Valentine, Jake C.; Morrissey, C. Orla; Tacey, Mark A.; Liew, Danny; Patil, Sushrut; Peleg, Anton Y.; Ananda-Rajah, Michelle R.

(2019), BMC INFECT DIS, 19(1), 274

DOI: 10.1186/s12879-019-3901-y

Global phylogenomics of multidrug-resistant Salmonella enterica serotype Kentucky ST198

Hawkey, Jane; Le Hello, Simon; Doublet, Benoît; Granier, Sophie A.; Hendriksen, Rene S.; Florian Fricke, W.; Ceyssens, Pieter Jan; Gomart, Camille; Billman-Jacobe, Helen; Holt, Kathryn E.; Weill, François Xavier

(2019), MICROBIOL GENOMICS, 5(7), 269

DOI: 10.1099/mgen.0.000269

Escherichia coli harboring mcr-1 in a cluster of liver transplant recipients

Macesic, Nenad; Khan, Sabrina; Giddins, Marla J.; Freedberg, Daniel E.; Whittier, Susan; Green, Daniel A.; Furuya, E. Yoko; Verna, Elizabeth C.; Annavajhala, Medini K.; Gomez-Simmonds, Angela; Uhlemann, Anne Catrin

(2019), ANTIMICROB AGENTS CH, 63(6), e02680-18.

DOI: 10.1128/AAC.02680-18

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

Rees, Vanessa E.; Deveson Lucas, Deanna S.; López-Causapé, Carla; Huang, Yuling; Kotsimbos, Tom; Bulitta, Jürgen B.; Rees, Murray C.; Barugahare, Adele; Peleg, Anton Y.; Nation, Roger L.; Oliver, Antonio; Boyce, John D.; Landersdorfer, Cornelia B.

(2019), ANTIMICROB AGENTS CH, 63(4), e02538-18.

DOI: 10.1128/AAC.02538-18

Distinct evolutionary dynamics of horizontal gene transfer in drug resistant and virulent clones of Klebsiella pneumoniae

Wyres, Kelly L.; Wick, Ryan R.; Judd, Louise M.; Froumine, Roni; Tokolyi, Alex; Gorrie, Claire L.; Lam, Margaret M.C.; Duchêne, Sebastián; Jenney, Adam; Holt, Kathryn E.

(2019), PLOS GENET, 15(4), e1008114.

DOI: 10.1371/journal.pgen.1008114