Research publications | Alfred Health

Structure and function of the open canalicular system–the platelet’s specialized internal membrane network

Selvadurai, Maria V.; Hamilton, Justin R.

(2018), Platelets, 29(4), 319-325

DOI: 10.1080/09537104.2018.1431388

A function-blocking PAR4 antibody is markedly antithrombotic in the face of a hyperreactive PAR4 variant

French, Shauna L.; Thalmann, Claudia; Bray, Paul F.; Macdonald, Lynn E.; Murphy, Andrew J.; Sleeman, Mark W.; Hamilton, Justin R.

(2018), Blood Adv, 2(11), 1283-1293

DOI: 10.1182/bloodadvances.2017015552

Profiling DNA methylation differences between inbred mouse strains on the Illumina Human Infinium MethylationEPIC microarray

Gujar, Hemant; Liang, Jane W.; Wong, Nicholas C.; Mozhui, Khyobeni

(2018), PLoS One, 13(3), 193496

DOI: 10.1371/journal.pone.0193496

Bone marrow defects and platelet function

Luu, Sarah; Gardiner, Elizabeth E.; Andrews, Robert K.

(2018), Cancers, 10(5), 147

DOI: 10.3390/cancers10050147

Maintenance Treatment and Survival in Patients with Myeloma

Gay, Francesca; Jackson, Graham; Rosi

(2018), JAMA Oncol, 4(10), 1389-1397

DOI: 10.1001/jamaoncol.2018.2961

Treatment Intensification With Autologous Stem Cell Transplantation and Lenalidomide Maintenance Improves Survival Outcomes of Patients With Newly Diagnosed Multiple Myeloma in Complete Response

Mina, Roberto; Petrucci, Maria Teresa; Corradini, Paolo; Spada, Stefano; Patriarca, Francesca; Cerrato, Chiara; De Paoli, Lorenzo; Pescosta, Norbert; Ria, Roberto; Malfitano, Alessandra; Musto, Pellegrino; Baldini, Luca; Guglielmelli, Tommasina; Gamberi, Barbara; Mannina, Donato; Benevolo, Giulia; Zambello, Renato; Falcone, Antonietta Pia; Palumbo, Antonio; Nagler, Arnon; Calafiore, Valeria; H

(2018), Clin Lymphoma Myeloma Leuk, 18(8), 533-540

DOI: 10.1016/j.clml.2018.05.019

Ibrutinib as treatment for patients with relapsed/refractory follicular lymphoma

Gopal, Ajay K.; Schuster, Stephen J.; Fowler, Nathan H.; Trotman, Judith; Hess, Georg; Hou, Jing Zhou; Yacoub, Abdulraheem; Lill, Michael; Martin, Peter; Vitolo, Umberto; Spencer, Andrew; Radford, John; Jurczak, Wojciech; Morton, James; Caballero, Dolores; Deshpande, Sanjay; Gartenberg, Gary J.; Wang, Shean Sheng; Damle, Rajendra N.; Schaffer, Michael; Balasubramanian, Sriram; Vermeulen, Jessica; Cheson, Bruce D.; Salles, Gilles

(2018), J Clin Oncol, 36(23), 2405-2412

DOI: 10.1200/JCO.2017.76.8853

The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection

Muscat, Andrea M.; Wong, Nicholas C.; Drummond, Katharine J.; Algar, Elizabeth M.; Khasraw, Mustafa; Verhaak, Roel; Field, Kathryn; Rosenthal, Mark A.; Ashley, David M.

(2018), Oncotarget, 9(8), 7844-7858

DOI: 10.18632/oncotarget.23541

MEF2C phosphorylation is required for chemotherapy resistance in acute myeloid leukemia

Brown, Fiona C.; Still, Eric; Koche, Richard P.; Yim, Christina Y.; Takao, Sumiko; Cifani, Paolo; Reed, Casie; Gunasekera, Shehana; Ficarro, Scott B.; Romanienko, Peter; Mark, Willie; McCarthy, Craig; de Stanchina, Elisa; Gonen, Mithat; Seshan, Venkatraman; Bhola, Patrick; O’Donnell, Conor; Spitzer, Barbara; Stutzke, Crystal; Lavall»e, Vincent Philippe; H»bert, Jos»e; Krivtsov, Andrei V.; Melnick, Ari; Paietta, Elisabeth M.; Tallman, Martin S.; Letai, Anthony; Sauvageau, Guy; Pouliot, Gayle; Levine, Ross; Marto, Jarrod A.; Armstrong, Scott A.; Kentsis, Alex

(2018), Cancer Discov, 8(4), 478-497

DOI: 10.1158/2159-8290.CD-17-1271

The Canonical Wnt/β-catenin Pathway as a Therapeutic Target in Multiple Myeloma

Savvidou, Ioanna; Khong, Tiffany; Spencer, Andrew; Alt, Karen Maria

(2018), ARCH MED RES, 6(7), 43480

Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells

Tremblay, Cedric; Saw, Jesslyn; Chiu, Sung Kai; Wong, Nicholas C.; Tsyganov, Kirill; Ghotb, Sarah; Graham, Alison N; Yan, Feng; Guirguis, Andrew; Sonderegger, Stefan; Lee, Nicole; Kalitsis, Paul; Reynolds, John; Ting, Stephen; Powell, David; Jane, Stephen; Curtis, David

(2018), Nat Commun, 9(1), 3535

DOI: 10.1038/s41467-018-06021-7

A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8

Bouhy, Delphine; Juneja, Manisha; Katona, Istvan; Holmgren, Anne; Asselbergh, Bob; De Winter, Vicky; Hochepied, Tino; Goossens, Steven; Haigh, Jody J.; Libert, Claude; Ceuterick-de Groote, Chantal; Irobi, Joy; Weis, Joachim; Timmerman, Vincent

(2018), Acta Neuropathol, 135(1), 131-148

DOI: 10.1007/s00401-017-1756-0

Contemporary analysis of functional immune recovery to opportunistic and vaccine-preventable infections after allogeneic haemopoietic stem cell transplantation

De Silva, Harini; Ffrench, Rosemary Ann; Korem, Maya; Orlowski-Oliver, Eva; Curtis, David John; Spencer, Andrew; Avery, Sharon; Patil, Sushrut; Morrissey, Catherine Orla

(2018), Clin Transl Immunology, 7(10), e1040

DOI: 10.1002/cti2.1040

A comparison of global coagulation assays between normal controls and patients with thrombocytopenia

Lim, Hui Yin; Leung, Patrick; Manitta, Vanessa; Nandurkar, Harshal; Ho, Prahlad

(2018), INT J LAB HEMATOL, 41(2), 184-191

DOI: 10.1111/ijlh.12941

Perinatal lethality of Par4–/– mice delivered by primiparous dams reveals spontaneous bleeding in mice without platelet thrombin receptor function

French, Shauna L.; Hamilton, Justin R.

(2018), Platelets, 29(2), 196-198

DOI: 10.1080/09537104.2017.1349310

Thrombin generation estimates the anticoagulation effect of direct oral anticoagulants with significant interindividual variability observed

Rigano, Joseph; Ng, Cheryl; Nandurkar, Harshal Hanumant; Ho, Prahlad

(2018), Blood Coagul Fibrinolysis, 29(2), 148-154

DOI: 10.1097/MBC.0000000000000678

An evaluation of global coagulation assays in myeloproliferative neoplasm

Lim, Hui Y.; Ng, Cheryl; Rigano, Joseph; Tacey, Mark Alan; Donnan, Geoffrey; Nandurkar, Harshal Hanumant; Ho, Prahlad Wei Soon

(2018), Blood Coagul Fibrinolysis, 29(3), 300-306

DOI: 10.1097/MBC.0000000000000724

Carfilzomib–dexamethasone versus subcutaneous or intravenous bortezomib in relapsed or refractory multiple myeloma

Goldschmidt, Hartmut; Moreau, Philippe; Ludwig, Heinz; Niesvizky, Ruben; Chng, Wee Joo; Joshua, Douglas; Weisel, Katja; Spencer, Andrew; Orlowski, Robert Z.; Feng, Shibao; Iskander, Karim S.; Dimopoulos, Meletios A.

(2018), Leuk Lymphoma, 59(6), 1364-1374

DOI: 10.1080/10428194.2017.1376743

Mechanisms of receptor shedding in platelets

Montague, Samantha J.; Andrews, Robert K.; Gardiner, Elizabeth E.

(2018), Blood, 132(24), 2535-2545

DOI: 10.1182/blood-2018-03-742668

Psammomys obesus

Chaudhary, Rajneesh; Walder, Ken R.; Hagemeyer, Christoph E.; Kanwar, Jagat R.

(2018), Curr Atheroscler Rep, 20(9), 46

DOI: 10.1007/s11883-018-0746-6