Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL

Sleebs BE, Kersten WJ, Kulasegaram S, Nikolakopoulos G, Hatzis E, Moss RM, Parisot JP, Yang H, Czabotar PE, Fairlie WD, Lee EF, Adams JM, Chen L, van Delft MF, Lowes KN, Wei A, Huang DC, Colman PM, Street IP, Baell JB, Watson K, Lessene G

(2013), J Med Chem, 56(13), 5514-40

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription

Thomas D, Powell JA, Vergez F, Segal DH, Nguyen NY, Baker A, Teh TC, Barry EF, Sarry JE, Lee EM, Nero TL, Jabbour AM, Pomilio G, Green BD, Manenti S, Glaser SP, Parker MW, Lopez AF, Ekert PG, Lock RB, Huang DC, Nilsson SK, Récher C, Wei AH, Guthridge MA

(2013), Blood, 122(5), 738-48

Utility of a clinical risk score to identify high-risk patients with de novo acute myeloid leukaemia in first remission after high-dose cytarabine (HiDAC) based induction chemotherapy

Ling V, Burnett AK, Bradstock K, Seymour JF, Hills RK, Wei A

(2013), Br J Haematol, 160(6), 861-3

Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival

Diakiw SM, Perugini M, Kok CH, Engler GA, Cummings N, To LB, Wei AH, Lewis ID, Brown AL, D'Andrea RJ

(2013), Br J Haematol, 161(6), 884-8

Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival

Thomas D, Powell JA, Green BD, Barry EF, Ma Y, Woodcock J, Fitter S, Zannettino AC, Pitson SM, Hughes TP, Lopez AF, Shepherd PR, Wei AH, Ekert PG, Guthridge MA

(2013), PLoS Biol, 11(3), e1001515

Stage I of a phase 2 study assessing the efficacy, safety, and tolerability of barasertib (AZD1152) versus low-dose cytosine arabinoside in elderly patients with acute myeloid leukemia

Kantarjian HM, Martinelli G, Jabbour EJ, Quintás-Cardama A, Ando K, Bay JO, Wei A, Gröpper S, Papayannidis C, Owen K, Pike L, Schmitt N, Stockman PK, Giagounidis A; SPARK-AML1 Investigators

(2013), Cancer, 19(14), 2611-9

Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma

Smeets MF, Chan AC, Dagger S, Bradley CK, Wei A, Izon DJ

(2013), PLoS One, 8(5), e62346

An update of consensus guidelines for warfarin reversal

Tran HA, Chunilal SD, Harper PL, Tran H, Wood EM, Gallus AS; Australasian Society of Thrombosis and Haemostasis (ASTH)

(2013), Med J Aust, 198(4), 198-9

Modulating T regulatory cells in cancer: how close are we?

Banerjee A, Vasanthakumar A, Grigoriadis G

(2013), Immunol Cell Biol, 91(5), 340-9

Thymic regulatory T cell development: role of signalling pathways and transcription factors

Engel M, Sidwell T, Vasanthakumar A, Grigoriadis G, Banerjee A

(2013), Clin Dev Immunol, 2013, 617595

Piloting the use of 2D barcode and patient safety-software in an Australian tertiary hospital setting

Miller K, Akers C, Magrin G, Whitehead S, Davis AK

(2013), Vox Sang, 105(2), 159-66

Tranexamic acid without prophylactic factor replacement for prevention of bleeding in hereditary bleeding disorder patients undergoing endoscopy: a pilot study

Davis A, Walsh M, McCarthy P, Brown G, Roberts S, Tran H, Street A, Fong CY, Kemp W

(2013), Haemophilia, 19(4), 583-9

Prevalence of transfusion-acquired hepatitis C in an Australian bleeding disorder population

Northcott MJ, Ong WL, Walsh M, McCarthy P, Belleli D, Tran H, Street A, Kemp W, Davis AK

(2013), Haemophilia, 19(6), 847-52

Central nervous system multiple myeloma--potential roles for intrathecal therapy and measurement of cerebrospinal fluid light chains

Lee D, Kalff A, Low M, Gangatharan S, Ho P, Bajel A, Ritchie D, Grigg A, Spencer A

(2013), Br J Haematol, 162(3), 371-5

An unusual case of microangiopathic haemolytic anaemia resulting from metastatic angiosarcoma

Fong CY, Low M

(2013), Blood, 122(1), 7

Effects of daily iron supplementation in primary-school-aged children: systematic review and meta-analysis of randomized controlled trials

Low M, Farrell A, Biggs BA, Pasricha SR

(2013), CMAJ, 185(17), E791-802

Macrophage migration inhibitory factor for the early prediction of infarct size

Chan W, White DA, Wang XY, Bai RF, Liu Y, Yu HY, Zhang YY, Fan F, Schneider HG, Duffy SJ, Taylor AJ, Du XJ, Gao W, Gao XM, Dart AM

(2013), J Am Heart Assoc, 2(5), e000226

Improved sensitivity of point of care troponin I values using reporting to below the 99th percentile of normals

Schneider HG, Ablitt P, Taylor J

(2013), Clin Biochem, 46(12), 979-82

Age-related reference intervals for bone turnover markers from an Australian reference population

Jenkins N, Black M, Paul E, Pasco JA, Kotowicz MA, Schneider HG

(2013), Bone, 55(2), 271-6

Prescribing trends before and after implementation of an antimicrobial stewardship program

Cairns KA, Jenney AW, Abbott IJ, Skinner MJ, Doyle JS, Dooley M, Cheng AC

(2013), Med J Aust, 198(5), 262-6

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