Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Pharmacological outcomes in teenagers with newly diagnosed epilepsy: A 30-year cohort study

Alsfouk, Bshra A.; Alsfouk, Aisha A.; Chen, Zhibin; Kwan, Patrick; Brodie, Martin J.

(2019), EPILEPSIA, 60(6), 1083-1090

DOI: 10.1111/epi.15664

Novel features for capturing temporal variations of rhythmic limb movement to distinguish convulsive epileptic and psychogenic nonepileptic seizures

Kusmakar, Shitanshu; Karmakar, Chandan; Yan, Bernard; Muthuganapathy, Ramanathan; Kwan, Patrick; O'Brien, Terence J.; Palaniswami, Marimuthu Swami

(2019), EPILEPSIA, 60(1), 165-174

DOI: 10.1111/epi.14619

Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: A Meta-Analysis of Individual Patient-Level Data

Campbell, Bruce C.V.; Majoie, Charles B.L.M.; Albers, Gregory W.; Menon, Bijoy K.; Yassi, Nawaf; Sharma, Gagan; van Zwam, Wim H.; van Oostenbrugge, Robert J.; Demchuk, Andrew M.; Guillemin, Francis; White, Philip; Dávalos, Antoni; van der Lugt, Aad; Butcher, Kenneth S.; Cherifi, Aboubaker; Marquering, Henk A.; Cloud, Geoffrey; Macho Fernández, Juan M.; Madigan, Jeremy; Oppenheim, Catherine; Donnan, Geoffrey A.; Roos, Yvo B.W.E.M.; Shankar, Jai; Lingsma, Hester; Bonafé, Alain; Raoult, Hélène; Hernández-Pérez, María; Bharatha, Aditya; Jahan, Reza; Jansen, Olav; Richard, Sébastien; Levy, Elad I.; Berkhemer, Olvert A.; Soudant, Marc; Aja, Lucia; Davis, Stephen M.; Krings, Timo; Tisserand, Marie; San Román, Luis; Tomasello, Alejandro; Beumer, Debbie; Brown, Scott; Liebeskind, David S.; Bracard, Serge; Muir, Keith W.; Dippel, Diederik W.J.; Goyal, Mayank; Saver, Jeffrey L.; Jovin, Tudor G.; Hill, Michael D.; Mitchell, Peter J.; ,

(2019), LANCET NEUROL, 18(1), 46-55

DOI: 10.1016/S1474-4422(18)30314-4

In search of antiepileptogenic treatments for post-traumatic epilepsy

Saletti, Patricia G.; Ali, Idrish; Casillas-Espinosa, Pablo M.; Semple, Bridgette D.; Lisgaras, Christos Panagiotis; Moshé, Solomon L.; Galanopoulou, Aristea S.

(2019), NEUROBIOL DIS, (123), 86-99

DOI: 10.1016/j.nbd.2018.06.017

Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures

Wang, Albert D.; Leong, Michelle; Johnstone, Benjamin; Rayner, Genevieve; Kalincik, Tomas; Roos, Izanne; Kwan, Patrick; O'Brien, Terence J.; Velakoulis, Dennis; Malpas, Charles B.

(2019), EPILEPSY RES, 158, 106234

DOI: 10.1016/j.eplepsyres.2019.106234

Raloxifene recovers effects of prenatal immune activation on cognitive task-induced gamma power

Schroeder, Anna; Nakamura, Jay P.; Hudson, Matthew; Jones, Nigel C.; Du, Xin; Sundram, Suresh; Hill, Rachel A.

(2019), PSYCHONEUROENDOCRINO, 110, 104448

DOI: 10.1016/j.psyneuen.2019.104448

Abbreviated assessment of psychopathology in patients with suspected seizure disorders

Malpas, Charles B.; Wang D., Albert; Leong, Michelle; Johnstone, Benjamin; Rayner, Genevieve; Kalincik, Tomas; Kwan, Patrick; O'Brien, Terence J.; Velakoulis, Dennis

(2019), EPILEPSY BEHAV, 100, 106530

DOI: 10.1016/j.yebeh.2019.106530

Personality profiles differ between patients with epileptic seizures and patients with psychogenic non-epileptic seizures

Leong, Michelle; Wang, Albert D.; Trainor, David; Johnstone, Ben; Rayner, Genevieve; Kalincik, Tomas; Roos, Izanne; Kwan, Patrick; O'Brien, Terence J.; Velakoulis, Dennis; Malpas, Charles B.

(2019), SEIZURE-EUR J EPILEP, (73), 1-8

DOI: 10.1016/j.seizure.2019.10.011

Ultra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals

Feng, Yen Chen Anne; Howrigan, Daniel P.; Abbott, Liam E.; Tashman, Katherine; Cerrato, Felecia; Singh, Tarjinder; Heyne, Henrike; Byrnes, Andrea; Churchhouse, Claire; Watts, Nick; Solomonson, Matthew; Lal, Dennis; Heinzen, Erin L.; Dhindsa, Ryan S.; Stanley, Kate E.; Cavalleri, Gianpiero L.; Hakonarson, H.; Helbig, Ingo; Krause, Roland; May, Patrick; Weckhuysen, S.; Petrovski, Slavé; Kamalakaran, Sitharthan; Sisodiya, Sanjay M.; Cossette, Patrick; Cotsapas, C.; De Jonghe, P.; Dixon-Salazar, T.; Guerrini, R.; Kwan, Patrick; Marson, Anthony G.; Stewart, R.; Depondt, Chantal; Dlugos, Dennis J.; Scheffer, Ingrid E.; Striano, Pasquale; Freyer, Catharine; McKenna, K.; Regan, Brigid M.; Bellows, Susannah T.; Leu, Costin; Bennett, Caitlin A.; Johns, Esther M.C.; Macdonald, Alexandra; Shilling, Hannah; Burgess, Rosemary; Weckhuysen, Dorien; Bahlo, Melanie; O'Brien, Terence J.; Todaro, Marian; Stamberger, Hannah; Andrade, Danielle M.; Sadoway, Tara R.; Mo, K.; Krestel, H.; Gallati, Sabina; Papacostas, Savvas S.; Kousiappa, Ioanna; Tanteles, George A.; Štěrbová, Katalin; Vlčková, Markéta; Sedláčková, L.; Laššuthová, P.; Klein, Karl Martin; Rosenow, F.; Reif, Philipp S.; Knake, Susanne; Kunz, Wolfram S.; Zsurka, Gábor; Elger, Christian E.; Bauer, Jürgen; Rademacher, Michael; Pendziwiat, Manuela; Muhle, Hiltrud; Rademacher, Annika; van Baalen, Andreas; von Spiczak, S.; Stephani, Ulrich; Afawi, Zaid; Korczyn, Amos D.; Kanaan, M.; Canavati, Christina; Kurlemann, Gerhard; Müller-Schlüter, K.; Kluger, Gerhard; Häusler, Martin; Blatt, Ilan; Lemke, Johannes R.; Krey, I.; Weber, Yvonne G.; Wolking, Stefan; Becker, Felicitas; Hengsbach, Christian; Rau, S.; Maisch, A. F.; Steinhoff, Bernhard J.; Schulze-Bonhage, Andreas; Schubert-Bast, Susanne; Schreiber, Herbert; Borggräfe, Ingo; Schankin, Christoph J.; Mayer, Thomas; Korinthenberg, Rudolf; Brockmann, Knut; Dennig, Dieter; Madeleyn, Rene; Kälviäinen, Reetta; Auvinen, Pia; Saarela, Anni; Linnankivi, T.; Lehesjoki, Anna Elina; Rees, Mark I.; Chung, Seo Kyung; Pickrell, William O.; Powell, Robert; Schneider, Natascha; Balestrini, Simona; Zagaglia, Sara; Braatz, Vera; Johnson, Michael R.; Auce, P.; Sills, Graeme J.; Baum, Larry W.; Sham, P. C.; Cherny, Stacey S.; Lui, Colin H.T.; Barišić, Nina; Delanty, Norman; Doherty, Colin P.; Shukralla, Arif; McCormack, Mark; El-Naggar, Hany; Canafoglia, L.; Franceschetti, Silvana; Castellotti, Barbara; Granata, Tiziana; Zara, Federico; Iacomino, Michele; Madia, Francesca; Vari, Maria Stella; Mancardi, Maria Margherita; Salpietro, Vincenzo; Bisulli, Francesca; Tinuper, P.; Licchetta, L.; Pippucci, Tommaso; Stipa, Carlotta; Minardi, Raffaella; Gambardella, Antonio; Labate, Angelo; Annesi, Grazia; Manna, Lorella; Gagliardi, Monica; Parrini, E.; Mei, Davide; Vetro, Annalisa; Bianchini, Claudia; Montomoli, Martino; Doccini, V.; Marini, C.; Suzuki, Toshimitsu; Inoue, Y.; Yamakawa, Kazuhiro; Tumiene, Birute; Sadleir, Lynette G.; King, Chontelle; Mountier, E.; Caglayan, S. Hande; Arslan, Mutluay; Yapıcı, Z.; Yis, Uluc; Topaloglu, Pınar; Kara, Bulent; Turkdogan, Dilsad; Gundogdu-Eken, Aslı; Bebek, Nerses; Uğur-İşeri, S.; Baykan, Betül; Salman, Barış; Haryanyan, G.; Yücesan, E.; Kesim, Yeşim; Özkara, Çiğdem; Poduri, Annapurna; Shiedley, Beth R.; Shain, Catherine; Buono, Russell J.; Ferraro, Thomas N.; Sperling, Michael R.; Lo, Warren; Privitera, Michael; French, Jacqueline A.; Schachter, Steven; Kuzniecky, Ruben I.; Devinsky, O.; Hegde, Manu; Khankhanian, P.; Helbig, Katherine L.; Ellis, Colin A.; Spalletta, Gianfranco; Piras, Fabrizio; Piras, Federica; Gili, Tommaso; Ciullo, Valentina; Reif, Andreas; McQuillin, Andrew; Bass, Nick; McIntosh, Andrew; Blackwood, Douglas; Johnstone, M.; Palotie, A.; Pato, Michele T.; Pato, Carlos N.; Bromet, Evelyn J.; Carvalho, Celia Barreto; Achtyes, Eric D.; Azevedo, Maria Helena; Kotov, R.; Lehrer, Douglas S.; Malaspina, Dolores; Marder, Stephen R.; Medeiros, Helena; Morley, Christopher P.; et al.

(2019), AM J HUM GENET, 105(2), 267-282

DOI: 10.1016/j.ajhg.2019.05.020

Transactive Response DNA-Binding Protein 43 Abnormalities after Traumatic Brain Injury

Tan, Xin Lin; Sun, Mujun; Brady, Rhys Daniel; Liu, Shijie; Llanos, Roxana M; Cheung, Steve; Wright, David Keith; Casillas-Espinosa, Pablo Miguel; Sashindranath, Maithili; O'Brien, Terence John; McDonald, Stuart J.; Turner, Bradley J; Shultz, Sandy

(2019), J NEUROTRAUM, 36(1), 87-99

DOI: 10.1089/neu.2017.5491

Tau Related Pathways as a Connecting Link between Epilepsy and Alzheimer's Disease

Paudel, Yam Nath; Angelopoulou, Efthalia; Jones, Nigel C.; O'brien, Terence J.; Kwan, Patrick; Piperi, Christina; Othman, Iekhsan; Shaikh, Mohd Farooq

(2019), ACS CHEM NEUROSCI, 10(10), 4199-4212

DOI: 10.1021/acschemneuro.9b00460

Randomized trial of add-on triheptanoin vs medium chain triglycerides in adults with refractory epilepsy

Borges K, Kaul N, Germaine J, Kwan P, O'Brien TJ

(2019), Epilepsia Open, 4(1), 153-63

DOI: 10.1002/epi4.12308

Limiting Neuronal Nogo Receptor 1 Signaling during Experimental Autoimmune Encephalomyelitis Preserves Axonal Transport and Abrogates Inflammatory Demyelination

Lee JY, Kim MJ, Thomas S, Oorschot V, Ramm G, Aui PM, Sekine Y, Deliyanti D, Wilkinson-Berka J, Niego B, Harvey AR, Theotokis P, McLean C, Strittmatter SM, Petratos S

(2019), J Neurosci, 39(28), 5562-80

DOI: 10.1523/JNEUROSCI.1760-18.2019

A systematic review protocol of timing, efficacy and cost effectiveness of upper limb therapy for motor recovery post-stroke

Hayward KS, Kramer SF, Thijs V, Ratcliffe J, Ward NS, Churilov L, Jolliffe L, Corbett D, Cloud G, Kaffenberger T, Brodtmann A, Bernhardt J, Lannin NA

(2019), Systematic Reviews, 8(1), 187

DOI: 10.1186/s13643-019-1093-6

Hospital organizational context and delivery of evidence-based stroke care: a cross-sectional study

Andrew NE, Middleton S, Grimley R, Anderson CS, Donnan GA, Lannin NA, Stroil-Salama E, Grabsch B, Kilkenny MF, Squires JE, Cadilhac DA; the Stroke123 Investigators

(2019), Implement Sci, 14(1), 6

DOI: 10.1186/s13012-018-0849-z

Prognosis of Acute Subdural Hematoma in the Elderly: A Systematic Review

Evans LR, Jones J, Lee HQ, Gantner D, Jaison A, Matthew J, Fitzgerald MC, Rosenfeld JV, Hunn MK, Tee JW

(2019), J NEUROTRAUM, 36(4), 517-22

DOI: 10.1089/neu.2018.5829

Prognosticating autoimmune encephalitis: A systematic review

Broadley J, Seneviratne U, Beech P, Buzzard K, Butzkueven H, O'Brien T, Monif M

(2019), J Autoimmun, 96, 24-34

DOI: 10.1016/j.jaut.2018.10.014

Ammirati innovation in neurosurgery

Brokeman M, Rosenfeld JV

(2019), In: Ethics in Neurosurgical Practice. Ed: S Honeybul. Cambridge University Press, Chapter 20,

Deep brain stimulation and psychosurgery

Komesarrof P, Rosenfeld JV

(2019), In: Ethics in Neurosurgical Practice. Ed: S Honeybul. Cambridge University Press, Chapter 18,

The brain-machine interface technology in neurosurgery

Rosenfeld JV, Broekman M

(2019), In: Ethics in Neurosurgical Practice. Ed: S Honeybul. Cambridge University Press, Chapter 22,