Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Accelerating early drug development: come on down under!

Wei A

(2017), Ann Oncol, 28(7), 1655-7

DOI: 10.1093/annonc/mdx101

Utility of CRISPR/Cas9 systems in hematology research

Lucas D, O'Leary HA, Ebert BL, Cowan CA, Tremblay CS

(2017), Exp Hematol, 54, 1-3

DOI: 10.1016/j.exphem.2017.06.006

Up-Regulation of the Vitamin D Pathway in Acute Myeloid Leukemia

Casan JML, Ghotb S, Morgan S, Wei AH, Ting SB

(2017), Ann Hematol Oncol, 4(3), 1141

Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel

Dàhner H, Estey E, Grimwade D, Amadori S, Appelbaum FR, B?chner T, Dombret H, Ebert BL, Fenaux P, Larson RA, Levine RL, Lo-Coco F, Naoe T, Niederwieser D, Ossenkoppele GJ, Sanz M, Sierra J, Tallman MS, Tien HF, Wei AH, Làwenberg B, Bloomfield CD

(2017), Blood, 129(4), 424-47

DOI: 10.1182/blood-2016-08-733196

Venetoclax and obinutuzumab in chronic lymphocytic leukemia

Fischer K, Al-Sawaf O, Fink AM, Dixon M, Bahlo J, Warburton S, Kipps TJ, Weinkove R, Robinson S, Seiler T, Opat S, Owen C, L?pez J, Humphrey K, Humerickhouse R, Tausch E, Frenzel L, Eichhorst B, Wendtner CM, Stilgenbauer S, Langerak AW, van Dongen JJM, Bàttcher S, Ritgen M, Goede V, Mobasher M, Hallek M

(2017), Blood, 129(19), 2702-5

DOI: 10.1182/blood-2017-01-761973

Challenges and opportunities in protease-activated receptor drug development

Hamilton JR, Trejo J

(2017), Annu Rev Pharmacol Toxicol, 57, 349-73

DOI: 10.1146/annurev-pharmtox-011613-140016

Malaria after international travel: a GeoSentinel analysis, 2003-2016

Angelo KM, Libman M, Caumes E, Hamer DH, Kain KC, Leder K, Grobusch MP, Hagmann SH, Kozarsky P, Lalloo DG, Lim PL, Patimeteeporn C, Gautret P, Odolini S, Chappuis F, Esposito DH; GeoSentinel Network

(2017), Malar J, 16, 293

DOI: 10.1186/s12936-017-1936-3

Lenalidomide maintenance compared with placebo in responding elderly patients with diffuse large B-cell lymphoma treated with first-line rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone

Thieblemont C, Tilly H, Gomes da Silva M, Casasnovas RO, Fruchart C, Morschhauser F, Haioun C, Lazarovici J, Grosicka A, Perrot A, Trotman J, Sebban C, Caballero D, Greil R, van Eygen K, Cohen AM, Gonzalez H, Bouabdallah R, Oberic L, Corront B, Choufi B, Lopez-Guillermo A, Catalano J, Van Hoof A, Briere J, Cabe¡adas J, Salles G, Gaulard P, Bosly A, Coiffier B

(2017), J Clin Oncol, 35(22), 2473-81

DOI: 10.1200/JCO.2017.72.6984

Diagnosis in subdural myeloid sarcoma

Lackey A, Laing B, Perkins A, Bryant M

(2017), Neuroradiol J, 30(3), 269-73

DOI: 10.1177/1971400916689343

Resveratrol mitigates trophoblast and endothelial dysfunction partly via activation of nuclear factor erythroid 2-related factor-2

Gurusinghe S, Cox AG, Rahman R, Chan ST, Muljadi R, Singh H, Leaw B, Mockler JC, Marshall SA, Murthi P, Lim R, Wallace EM

(2017), Placenta, 60, 74-85

DOI: 10.1016/j.placenta.2017.10.008

The Snail Family in Normal and Malignant Haematopoiesis

Carmichael CL, Haigh JJ

(2017), Cells Tissues Organs, 203(2), 82-98

DOI: 10.1159/000448655

Grainyhead-like 3 (Grhl3) deficiency in brain leads to altered locomotor activity and decreased anxiety-like behaviors in aged mice

Dworkin S, Auden A, Partridge DD, Daglas M, Medcalf RL, Mantamadiotis T, Georgy SR, Darido C, Jane SM, Ting SB

(2017), Dev Neurobiol, 77(6), 775-88

DOI: 10.1002/dneu.22469

Did He Who Made the Lamb Make Thee? New Developments in Treating the Fearful Symmetry of Acute Myeloid Leukemia

Brumatti G, Lalaoui N, Wei AH, Silke J

(2017), Trends Mol Med, 23(3), 264-281

DOI: 10.1016/j.molmed.2017.01.005

Myeloma in the real world: what is really happening?

Bergin K, McQuilten Z, Moore E, Wood E, Spencer A

(2017), Clin Lymphoma Myeloma Leuk, 17(3), 133-44.e1

DOI: 10.1016/j.clml.2016.12.002

The mTOR inhibitor everolimus in combination with azacitidine in patients with relapsed/refractory acute myeloid leukemia

Tan P, Tiong IS, Fleming S, Pomilio G, Cummings N, Droogleever M, McManus J, Schwarer A, Catalano J, Patil S, Avery S, Spencer A, Wei A

(2017), Oncotarget, 8(32), 52269-80

DOI: 10.18632/oncotarget.13699

Blinatumomab versus chemotherapy for advanced acute lymphoblastic leukemia

Kantarjian H, Stein A, Gàkbuget N, Fielding AK, Schuh AC, Ribera JM, Wei A, Dombret H, Foá R, Bassan R, Arslan Ö, Sanz MA, Bergeron J, Demirkan F, Lech-Maranda E, Rambaldi A, Thomas X, Horst HA, Br?ggemann M, Klapper W, Wood BL, Fleishman A, Nagorsen D, Holland C, Zimmerman Z, Topp MS

(2017), N Engl J Med, 376(9), 836-47

DOI: 10.1056/NEJMoa1609783

Metabolic gatekeeper function of B-lymphoid transcription factors

Chan LN, Chen Z, Braas D, Lee JW, Xiao G, Geng H, Cosgun KN, Hurtz C, Shojaee S, Cazzaniga V, Schjerven H, Ernst T, Hochhaus A, Kornblau SM, Konopleva M, Pufall MA, Cazzaniga G, Liu GJ, Milne TA, Koeffler HP, Ross TS, S?nchez-GarcÃa I, Borkhardt A, Yamamoto KR, Dickins RA, Graeber TG, M?schen M

(2017), Nature, 542(7642), 479-83

DOI: 10.1038/nature21076

Idarubicin Dose Escalation During Consolidation Therapy for Adult Acute Myeloid Leukemia

Bradstock KF, Link E, Di Iulio J, Szer J, Marlton P, Wei AH, Enno A, Schwarer A, Lewis ID, D'Rozario J, Coyle L, Cull G, Campbell P, Leahy MF, Hahn U, Cannell P, Tiley C, Lowenthal RM, Moore J, Cartwright K, Cunningham I, Taper J, Grigg A, Roberts AW, Benson W, Hertzberg M, Deveridge S, Rowlings P, Mills AK, Gill D, Bardy P, Campbell L, Seymour JF; Australasian Leukaemia & Lymphoma Group

(2017), J Clin Oncol, 35(15), 1678-85

DOI: 10.1200/JCO.2016.70.6374

Circulating tumour DNA analysis demonstrates spatial mutational heterogeneity that coincides with disease relapse in myeloma

Mithraprabhu S, Khong T, Ramachandran M, Chow A, Klarica D, Mai L, Walsh S, Broemeling D, Marziali A, Wiggin M, Hocking J, Kalff A, Durie B, Spencer A

(2017), Leukemia, 31(8), 1695-705

DOI: 10.1038/leu.2016.366

Partial response after induction chemotherapy has clinical relevance in acute myeloid leukaemia

Fleming S, Ong DM, Jackson K, Avery S, Mollee P, Marlton P, Kennedy G, Wei AH

(2017), Br J Haematol, 177(2), 328-30

DOI: 10.1111/bjh.14063

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