Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals.

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Urinary antibacterial activity of fosfomycin and nitrofurantoin at registered dosages in healthy volunteers

Wijma, Rixt A.; Huttner, Angela; van Dun, Sven; Kloezen, Wendy; Abbott, Iain J.; Muller, Anouk E.; Koch, Birgit C.P.; Mouton, Johan W.

(2019), INT J ANTIMICROB AG, 54(4), 435-441.

DOI: 10.1016/j.ijantimicag.2019.07.018

Identification of 5-Substituted 2-Acylaminothiazoles That Activate Tat-Mediated Transcription in HIV-1 Latency Models

Nguyen, William; Jacobson, Jonathan; Jarman, Kate E.; Jousset Sabroux, Helene; Harty, Leigh; McMahon, James; Lewin, Sharon R.; Purcell, Damian F.; Sleebs, Brad E.

(2019), J MED CHEM, 62(10), 5148-5175.

DOI: 10.1021/acs.jmedchem.9b00462

Infectious diseases physician attitudes to long-term antibiotic use

Kiss, Christopher R.; Lau, Jillian S.Y.; Yeung, Alex; Woolley, Ian

(2019), INT J CLIN PHARM-NET, 41(1), 18-21.

DOI: 10.1007/s11096-018-00781-4

Differential Roles of Plasma Protein Corona on Immune Cell Association and Cytokine Secretion of Oligomeric and Fibrillar Beta-Amyloid

Faridi, Ava; Yang, Wen; Kelly, Hannah Gabrielle; Wang, Chuanyu; Faridi, Pouya; Purcell, Anthony Wayne; Davis, Thomas P.; Chen, Pengyu; Kent, Stephen J.; Ke, Pu Chun

(2019), BIOMACROMOLECULES, 20(11), 4208-4217.

DOI: 10.1021/acs.biomac.9b01116

Synergistic meropenem-tobramycin combination dosage regimens against clinical hypermutable Pseudomonas aeruginosa at simulated epithelial lining fluid concentrations in a dynamic biofilm model.

Bilal, Hajira; Bergen, Phillip J.; Kim, Tae Hwan; Chung, Seung Eun; Peleg, Anton Y.; Oliver, Antonio; Nation, Roger L.; Landersdorfer, Cornelia B.

(2019), ANTIMICROB AGENTS CH, 63(11, e01293-19)

DOI: 10.1128/AAC.01293-19

The pharmacokinetics of nitrofurantoin in healthy female volunteers

Huttner, Angela; Wijma, Rixt A.; Stewardson, Andrew J.; Olearo, Flaminia; Von Dach, Elodie; Harbarth, Stephan; Brüggemann, Roger J.M.; Mouton, Johan W.; Muller, Anouk E.

(2019), J ANTIMICROB CHEMOTH, 74(6), 1656-1661.

DOI: 10.1093/jac/dkz095

Evolution of daptomycin resistance in coagulase-negative staphylococci involves mutations of the essential two-component regulator WALKR

Jiang, Jhih-Hang; Dexter, Carina; Cameron, David R.; Monk, Ian R.; Baines, Sarah L.; Abbott, Iain J.; Spelman, Denis W.; Kostoulias, Xenia; Nethercott, Cara; Howden, Benjamin P.; Peleg, Anton Y.

(2019), ANTIMICROB AGENTS CH, 63(3), e01926-18.

DOI: 10.1128/AAC.01926-18

The Mechanisms of Disease Caused by Acinetobacter baumannii

Morris, Faye C.; Dexter, Carina; Kostoulias, Xenia; Uddin, Muhammad Ikhtear; Peleg, Anton Y.

(2019), FRONT MICROBIOL, 10, 1601

DOI: 10.3389/fmicb.2019.01601

Antibiotic resistance and host immune evasion in Staphylococcus aureus mediated by a metabolic adaptation

Jiang, Jhih-Hang; Bhuiyan, Md Saruar; Shen, Hsin-Hui; Cameron, David R.; Rupasinghe, Thusitha W.T.; Wu, Chun Ming; Le Brun, Anton P.; Kostoulias, Xenia; Domene, Carmen; Fulcher, Alex J.; McConville, Malcolm J.; Howden, Benjamin P.; Lieschke, Graham J.; Peleg, Anton Y.

(2019), P NATL ACAD SCI USA, 116(9), 3722-3727.

DOI: 10.1073/pnas.1812066116

Strategies to reduce non-ventilator-associated hospital-acquired pneumonia

Mitchell, Brett G.; Russo, Philip L.; Cheng, Allen C.; Stewardson, Andrew J.; Rosebrock, Hannah; Curtis, Stephanie J.; Robinson, Sophia; Kiernan, Martin

(2019), Infect Dis Health, 24(4), 229-239.

DOI: 10.1016/j.idh.2019.06.002

Influenza Epidemiology, Vaccine Coverage and Vaccine Effectiveness in Children Admitted to Sentinel Australian Hospitals in 2017

Blyth, Christopher C.; Macartney, Kristine K.; McRae, Jocelynne; Clark, Julia E.; Marshall, Helen S.; Buttery, Jim; Francis, Joshua R.; Kotsimbos, Tom; Kelly, Paul M.; Cheng, Allen C.; ,

(2019), CLIN INFECT DIS, 68(6), 940-948.

DOI: 10.1093/cid/ciy597

Effect of carbapenem resistance on outcomes of bloodstream infection caused by Enterobacteriaceae in low-income and middle-income countries (PANORAMA)

Stewardson, Andrew J.; Marimuthu, Kalisvar; Sengupta, Sharmila; Allignol, Arthur; El-Bouseary, Maisra; Carvalho, Maria J.; Hassan, Brekhna; Delgado-Ramirez, Monica A.; Arora, Anita; Bagga, Ruchika; Owusu-Ofori, Alex K.; Ovosi, Joseph O.; Aliyu, Shamsudin; Saad, Hala; Kanj, Souha S.; Khanal, Basudha; Bhattarai, Balkrishna; Saha, Samir K.; Uddin, Jamal; Barman, Purabi; Sharma, Latika; El-Banna, Tarek; Zahra, Rabaab; Saleemi, Mansab Ali; Kaur, Amarjeet; Iregbu, Kenneth; Uwaezuoke, Nkolika SC; Abi Hanna, Pierre; Feghali, Rita; Correa, Ana L.; Munera, Maria I.; Le, Thi Anh Thu; Tran, Thi Thanh Nga; Phukan, Chimanjita; Phukan, Chiranjita; Valderrama-Beltrán, Sandra L.; Alvarez-Moreno, Carlos; Walsh, Timothy R.; Harbarth, Stephan

(2019), LANCET INFECT DIS, 19(6), 601-610.

DOI: 10.1016/S1473-3099(18)30792-8

Cardiovascular disease and diabetes in HIV-positive and HIV-negative gay and bisexual men over the age of 55 years in Australia

Puhr, R.; Petoumenos, K.; Huang, R.; Templeton, D. J.; Woolley, I.; Bloch, M.; Russell, D.; Law, M. G.; Cooper, D. A.

(2019), HIV MED, 20(2), 121-130.

DOI: 10.1111/hiv.12689

Outcomes of an electronic medical record (EMR)-driven intensive care unit (ICU)-antimicrobial stewardship (AMS) ward round

Devchand, Misha; Stewardson, Andrew J.; Urbancic, Karen F.; Khumra, Sharmila; Mahony, Andrew A.; Walker, Steven; Garrett, Kent; Lindsay Grayson, M.; Trubiano, Jason A.

(2019), INFECT CONT HOSP EP, 40(10), 1170-1175.

DOI: 10.1017/ice.2019.218

Individual and community predictors of urinary ceftriaxone-resistant Escherichia coli isolates, Victoria, Australia

Chua, Kyra Y.L.; Stewardson, Andrew J.

(2019), ANTIMICROB RESIST IN, 8, 36

DOI: 10.1186/s13756-019-0492-8

Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection (GEMINI-1 and GEMINI-2)

Cahn, Pedro; Madero, Juan Sierra; Arribas, José Ramón; Antinori, Andrea; Ortiz, Roberto; Clarke, Amanda E.; Hung, Chien Ching; Rockstroh, Jürgen K.; Girard, Pierre Marie; Sievers, Jörg; Man, Choy; Currie, Alexander; Underwood, Mark; Tenorio, Allan R.; Pappa, Keith; Wynne, Brian; Fettiplace, Anna; Gartland, Martin; Aboud, Michael; Smith, Kimberly; Cassetti, Lidia; David, Daniel; Figueras, Laura; Losso, Marcelo; Lopardo, Gustavo; Lupo, Sergio; Porteiro, Norma; Sánchez, Marisa; Bloch, Mark; Cooper, David; Finlayson, Robert; Kelleher, Anthony; Koh, Kenneth; Lewis, David; McMahon, James; Moore, Richard; Roth, Norman; Shields, Matthew; De Wit, Stephane; Florence, Eric; Goffard, Jean Christophe; Demeester, Remy; Lacor, Patrick; Vandercam, Bernard; Vandekerckhove, Linos; Angel, Jonathan; Baril, Jean Guy; Conway, Brian; De Pokomandy, Alexandra; Szabo, Jason; Walmsley, Sharon; Bouchaud, Olivier; Chidiac, Christian; Delobel, Pierre; Goujard, Cecile; Katlama, Christine; Molina, Jean Michel; Pialoux, Gilles; Philibert, Patrick; Bogner, Johannes; Esser, Stefan; Krznaric, Ivanka; Lehmann, Clara; Spinner, Christoph; Stellbrink, Hans Jurgen; Stephan, Christoph; Stoehr, Albrecht; Barchi, Enrico; Caramello, Pietro; Castelli, Francesco; Cattelan, Anna Maria; D'Arminio Monforte, Antonella; Di Biagio, Antonio; Di Perri, Giovanni; Gori, Andrea; Maggiolo, Franco; Menzaghi, Barbara; Migliorino, Guglielmo; Mussini, Cristina; Penco, Giovanni; Puoti, Massimo; Rizzardini, Giuliano; Gulminetti, Roberto; Lazzarin, Adriano; Quirino, Tiziano; Sighinolfi, Laura; Viale, Pierluigi; Amaya Tapia, Gerardo; Andrade Villanueva, Jaime; Granados Reyes, Enrique R.; Perez Rios, Alma; Santoscoy Gomez, Mario; Den Hollander, Jan; Rijnders, Bart; Hidalgo, José A.; Hercilla Vasquez, Luis; Illescas, Luis; Olczak, Anita; Mansinho, Kamal; Correia Pacheco, Patricia Paula; Teófilo, Eugénio; Saraiva da Cunha, Jose; Sarmento e Castro, Rui; Serrão, Rosário; Arbune, Manuela; Jianu, Cristian; Oprea, Anca; Preotescu, Liliana; Prisacariu, Liviu Jany; Belonosova, Elena; Borodkina, Olga; Chernova, Oxana; Gankina, Natalia; Kizhlo, Svetlana; Kulagin, Valeriy; Kurina, Nadezhda; Nagimova, Firaya; Pokrovsky, Vadim; Ryamova, Elena; Voronin, Evgeny; Yakovlev, Alexey; Kaplan, Richard; Lee, Sun Hee; Kim, Shin Woo; Kim, Sang Il; Kim, Woo Joo; Antela Lopez, Antonio; Casado Osorio, Jose L.; Castaño Carracedo, Manuel A.; De Los Santos Gil, Ignacio; Estrada Perez, Vicente; Falco Ferrer, Vicenç; Force, Luis; Galinda Puerto, Maria Jose; Garcia Deltoro, Miguel; Gatell, Josep M.; Goenaga Sanchez, Miguel A.; González Cordón, Ana; Knobel, Hernando; Lopez Bernaldo de Quiros, Juan Carlos; Losa Garcia, Juan E.; Masia, Mar; Montero-Alsonso, Marta; Ocampo Hermida, Antonio; Pasquau Liaño, Juan; Portilla Sogorb, Joaquin; Pulido Ortega, Federico; Rivera Roman, Antonio; Santos Fernandez, Jose Ramon; Torres Perea, Rafael; Troya Garcia, Jesus; Viciana Fernandez, Pompeyo; Calmy, Alexandra; Hauser, Christoph; Fehr, Jan; Cheng, Shu Hsing; Ko, Wen Chien; Lin, Hsi Hsun; Lu, Po Liang; Tseng, Yu Ting; Wang, Ning Chi; Wong, Wing Wai; Yang, Chia Jui; Arduino, Roberto; Benson, Paul; Berhe, Mezgebe; Bredeek, Fritz; Brinson, Cynthia; Campbell, Thomas; Crofoot, Gordon; Cunningham, Douglas; DeJesus, Edwin; Dretler, Robin; Eron, Joseph; Fife, Kenneth; Fichtenbaum, Carl; Flamm, Jason; Goldstein, Deborah; Gupta, Samir; Hagins, Debbie; Hoffman-Terry, Margaret; Jayaweera, Dushyantha; Kinder, Clifford; Klein, Daniel; McDonald, Cheryl; Mills, Anthony; Nahass, Ronald; Osiyemi, Olayemi; Overton, Edgar; Parks, David; Prelutsky, David; Ramgopal, Moti; Schrader, Shannon; Sha, Beverly; Simon, Gary; Sims, James; Skiest, Daniel; Slim, Jihad; Tashima, Karen; Thedinger, Blair; Gazzard, Brian; Fox, Julie; Johnson, Margaret; Kegg, Stephen; Khoo, Saye; Mazhude, Charles; Orkin, Chloe; Schembri, Gabriel; Ustianowski, Andrew; ,

(2019), LANCET, 393(10167), 143-155.

DOI: 10.1016/S0140-6736(18)32462-0

Colonizing multidrug-resistant bacteria and the longitudinal evolution of the intestinal microbiome after liver transplantation

Annavajhala, Medini K.; Gomez-Simmonds, Angela; Macesic, Nenad; Sullivan, Sean B.; Kress, Anna; Khan, Sabrina D.; Giddins, Marla J.; Stump, Stephania; Kim, Grace I.; Narain, Ryan; Verna, Elizabeth C.; Uhlemann, Anne-Catrin

(2019), NAT COMMUN, 10(1), 4715

DOI: 10.1038/s41467-019-12633-4

Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome Is Associated With Dysregulation of IL-7/IL-7 Receptor Signaling Pathway in T Cells and Monocyte Activation

Akilimali, Ngomu Akeem; Muema, Daniel M.; Specht, Charles; Chang, Christina C.; Moosa, Mahomed Yunus S.; Levitz, Stuart M.; Lewin, Sharon R.; French, Martyn A.; Ndungʼu, Thumbi

(2019), JAIDS-J ACQ IMM DEF, 80(5), 596-604.

DOI: 10.1097/QAI.0000000000001946

Spectrum of illness among returned Australian travellers from Bali, Indonesia

Sohail, Asma; McGuinness, Sarah L.; Lightowler, Rachel; Leder, Karin; Jomon, Bismi; Bain, Christopher A.; Peleg, Anton Y.

(2019), INTERN MED J, 49(1), 34-40.

DOI: 10.1111/imj.13993

The World Association against Infection in Orthopaedics and Trauma (WAIOT) procedures for Microbiological Sampling and Processing for Periprosthetic Joint Infections (PJIs) and other Implant-Related Infections

Drago, Lorenzo; Clerici, Pierangelo; Morelli, Ilaria; Ashok, Johari; Benzakour, Thami; Bozhkova, Svetlana; Alizadeh, Chingiz; del Sel, Hernán; Sharma, Hemant K; Peel, Trisha; Mattina, Roberto; Romanò, Carlo Luca

(2019), J CLIN MED, 8(7), 933

DOI: 10.3390/jcm8070933

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