Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Multiple sclerosis

Clough, Meaghan; Foletta, Paige Joan; Frohman, Ashley N; Frohman, Elliot; Sears, Derek; White, Owen Bruce; Fielding, Joanne

(2018), Mult Scler J, 4(2), 2055217318771781

DOI: 10.1177/2055217318771781

Novel functional MRI task for studying the neural correlates of upper limb tremor

Boonstra, Frederique M.C.; Perera, Thushara; Noffs, Gustavo; Marotta, Cassandra; Vogel, Adam P.; Evans, Andrew H.; Butzkueven, Helmut; Moffat, Bradford A.; van der Walt, Anneke; Kolbe, Scott C.

(2018), Front Neurol, 9, 513

DOI: 10.3389/fneur.2018.00513

Neuropeptide Y affects thalamic reticular nucleus neuronal firing and network synchronization associated with suppression of spike-wave discharges

Ali, Idrish; Gandrathi, Arun; Zheng, Thomas; Morris, Margaret J.; O'Brien, Terence J.; French, Chris

(2018), Epilepsia, 59(7), 1444-1454

DOI: 10.1111/epi.14451

Gene therapy mediated seizure suppression in Genetic Generalised Epilepsy

Powell, Kim L.; Fitzgerald, Xavier; Shallue, Claire; Jovanovska, Valentina; Klugmann, Matthias; Von Jonquieres, Georg; O'Brien, Terence J.; Morris, Margaret J.

(2018), Neurobiol Dis, 113(2), 23-32

DOI: 10.1016/j.nbd.2018.01.016

The influence of immunological stressors on traumatic brain injury

Sun, Mujun; McDonald, Stuart J.; Brady, Rhys D.; O'Brien, Terence J.; Shultz, Sandy R.

(2018), Brain Behav Immun, 69, 618-628

DOI: 10.1016/j.bbi.2018.01.007

Telomere length and advanced diffusion MRI as biomarkers for repetitive mild traumatic brain injury in adolescent rats

Wright, David K.; O'Brien, Terence J.; Mychasiuk, Richelle; Shultz, Sandy R.

(2018), NeuroImage Clin, 18, 315-324

DOI: 10.1016/j.nicl.2018.01.033

The phenotype of bilateral hippocampal sclerosis and its management in “real life” clinical settings

Sen, Arjune; Dugan, Patricia; Perucca, Piero; Costello, Daniel; Choi, Hyunmi; Bazil, Carl; Radtke, Rod; Andrade, Danielle; Depondt, Chantal; Heavin, Sinead; Adcock, Jane; Pickrell, W. Owen; McGinty, Ronan; Nascimento, Fábio; Smith, Philip; Rees, Mark I.; Kwan, Patrick; O'Brien, Terence J.; Goldstein, David; Delanty, Norman

(2018), Epilepsia, 59(7), 1410-1420

DOI: 10.1111/epi.14436

Repeated mild traumatic brain injury can cause acute neurologic impairment without overt structural damage in juvenile rats

Meconi, Alicia; Wortman, Ryan C.; Wright, David K.; Neale, Katie J.; Clarkson, Melissa; Shultz, Sandy R.; Christie, Brian R.

(2018), PLoS One, 13(5), e0197187

DOI: 10.1371/journal.pone.0197187

Human Ischaemic Cascade Studies Using SH-SY5Y Cells

Liu, Ye; Eaton, Emma D.; Wills, Taryn E.; McCann, Sarah K.; Antonic, Ana; Howells, David W.

(2018), TRANSL STROKE RES, 9(6), 564-574

DOI: 10.1007/s12975-018-0620-4

Derivation of phenotypically diverse neural culture from hESC by combining adherent and dissociation methods

Liu, Ye; Antonic, Ana; Yang, Xuan; Korte, Nils; Lim, Katherine; Michalska, Anna E.; Dottori, Mirella; Howells, David W.

(2018), J Neurosci Methods, 308, 286-293

DOI: 10.1016/j.jneumeth.2018.07.005

NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons

Antonic, Ana; Dottori, Mirella; Macleod, Malcolm R.; Donnan, Geoffrey A.; Howells, David W.

(2018), J Stroke Cerebrovasc Dis, 27(8), 2158-2165

DOI: 10.1016/j.jstrokecerebrovasdis.2018.03.015

Gambogic amide, a selective TrkA agonist, does not improve outcomes from traumatic brain injury in mice

Johnstone, Maddison R.; Sun, Mujun; Taylor, Caroline J.; Brady, Rhys D.; Grills, Brian L.; Church, Jarrod E.; Shultz, Sandy R.; McDonald, Stuart J.

(2018), Brain Inj, 32(2), 257-268

DOI: 10.1080/02699052.2017.1394492

Mild traumatic brain injury in adolescent mice alters skull bone properties to influence a subsequent brain impact at adulthood

McColl, Thomas J.; Brady, Rhys D.; Shultz, Sandy R.; Lovick, Lauren; Webster, Kyria M.; Sun, Mujun; McDonald, Stuart J.; O'Brien, Terence J.; Semple, Bridgette D.

(2018), Front Neurol, 9, 372

DOI: 10.3389/fneur.2018.00372

CaV3.2 drives sustained burst-firing, which is critical for absence seizure propagation in reticular thalamic neurons

Cain, Stuart M.; Tyson, John R.; Choi, Hyun Beom; Ko, Rebecca; Lin, Paulo J.C.; Ledue, Jeffrey M.; Powell, Kim L.; Bernier, Louis Philippe; Rungta, Ravi L.; Yang, Yi; Cullis, Pieter R.; O'Brien, Terence J.; Macvicar, Brian A.; Snutch, Terrance P.

(2018), Epilepsia, 59(4), 778-791

DOI: 10.1111/epi.14018

Genetics of focal epilepsies

Perucca, Piero

(2018), EPILEPSY CURR, 18(6), 356-362

DOI: 10.5698/1535-7597.18.6.356

Diffusion MRI abnormalities in adolescent rats given repeated mild traumatic brain injury

Wortman, Ryan C.; Meconi, Alicia; Neale, Katie J.; Brady, Rhys D.; McDonald, Stuart J.; Christie, Brian R.; Wright, David K.; Shultz, Sandy R.

(2018), Ann Clin Transl Neurol, 5(12), 1588-1598

DOI: 10.1002/acn3.667

Association of Inflammation and Disability Accrual in Patients with Progressive-Onset Multiple Sclerosis

Hughes, Jordana; Jokubaitis, Vilija; Lugaresi, Alessandra; Hupperts, Raymond; Izquierdo, Guillermo; Prat, Alexandre; Girard, Marc; Duquette, Pierre; Grand'maison, Francois; Grammond, Pierre; Sola, Patrizia; Ferraro, DIana; Ramo-Tello, Cristina; Trojano, Maria; Slee, Mark; Shaygannejad, Vahid; Boz, Cavit; Lechner-Scott, Jeanette; Van Pesch, Vincent; Pucci, Eugenio; Solaro, Claudio; Verheul, Freek; Terzi, Murat; Granella, Franco; Spitaleri, Daniele; Alroughani, Raed; Jun, Jae Kwan; Fambiatos, Adam; Van Der Walt, Anneke; Butzkueven, Helmut; Kalincik, Tomas; ,

(2018), JAMA Neurol, 75(11), 1407-1415

DOI: 10.1001/jamaneurol.2018.2109

Oculomotor Cognitive Control Abnormalities in Australian Rules Football Players with a History of Concussion

Clough, Meaghan; Mutimer, Steven; Wright, David K.; Tsang, Adrian; Costello, Daniel M.; Gardner, Andrew J.; Stanwell, Peter; Mychasiuk, Richelle; Sun, Mujun; Brady, Rhys D.; McDonald, Stuart J.; Webster, Kyria M.; Johnstone, Maddison R.; Semple, Bridgette D.; Agoston, Denes V.; White, Owen B.; Frayne, Richard; Fielding, Joanne; O'Brien, Terence J.; Shultz, Sandy R.

(2018), J Neurotrauma, 35(5), 730-738

DOI: 10.1089/neu.2017.5204

The Study of Neurocognitive Outcomes, Radiological and Retinal Effects of Aspirin in Sleep Apnoea- rationale and methodology of the SNORE-ASA study

Ward, Stephanie Alison; Storey, Elsdon; Woods, Robyn L.; Hamilton, Garun S.; Kawasaki, Ryo; Janke, Andrew L.; Naughton, Matthew T.; O'Donoghue, Fergal; Wolfe, Rory; Wong, Tien Y.; Reid, Christopher M.; Abhayaratna, Walter P.; Stocks, Nigel; Trevaks, Ruth; Fitzgerald, Sharyn; Hodgson, Lauren A.B.; Robman, Liubov; Workman, Barbara; McNeil, John J.; ,

(2018), Contemp Clin Trials, 64, 101-111.

DOI: 10.1016/j.cct.2017.10.016

Delivery of full predicted energy from nutrition and the effect on mortality in critically ill adults

Ridley, Emma J.; Davies, Andrew R.; Hodgson, Carol L.; Deane, Adam; Bailey, Michael; Cooper, D. Jamie

(2018), Clin Nutr, 37(6), 1913-1925

DOI: 10.1016/j.clnu.2017.09.026