Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Global regulator MorA affects virulence-associated protease secretion in Pseudomonas aeruginosa PAO1

Ravichandran A, Ramachandran M, Suriyanarayanan T, Wong CC, Swarup S

(2015), PLoS One, 10(4), e0123805

The platelet Fc receptor, FcγRIIa

Qiao J, Al-Tamimi M, Baker RI, Andrews RK, Gardiner EE

(2015), Immunol Rev, 268(1), 241-52

Methods to determine the lagrangian shear experienced by platelets during thrombus growth

Pinar IP, Arthur JF, Andrews RK, Gardiner EE, Ryan K, Carberry J

(2015), PLoS One, 10(12), e0144860

Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9

Phillipson LJ, Segal DH, Nero TL, Parker MW, Wan SS, de Silva M, Guthridge MA, Wei AH, Burns CJ

(2015), Bioorg Med Chem, 23(19), 6280-96

Asymmetric cell division during T cell development controls downstream fate

Pham K, Shimoni R, Charnley M, Ludford-Menting MJ, Hawkins ED, Ramsbottom K, Oliaro J, Izon D, Ting SB, Reynolds J, Lythe G, Molina-Paris C, Melichar H, Robey E, Humbert PO, Gu M, Russell SM

(2015), J Cell Biol, 210(6), 933-50

MYB elongation is regulated by the nucleic acid binding of NFΚB p50 to the intronic stem-loop region

Pereira LA, Hugo HJ, Malaterre J, Huiling X, Sonza S, Cures A, Purcell DF, Ramsland PA, Gerondakis S, Gonda TJ, Ramsay RG

(2015), PLoS One, 10(4), e0122919

Loss of c-REL but not NF-ΚB2 prevents autoimmune disease driven by FasL mutation

O'Reilly LA, Hughes P, Lin A, Waring P, Siebenlist U, Jain R, Gray DH, Gerondakis S, Strasser A

(2015), Cell Death Differ, 22(5), 767-78

Class II but not second class-prospects for the development of class II PI3K inhibitors

Mountford SJ, Zheng Z, Sundaram K, Jennings IG, Hamilton JR, Thompson PE

(2015), ACS Med Chem Lett, 6(1), 3-6

The class II PI 3-kinase, PI3KC2{alpha}, links platelet internal membrane structure to shear-dependent adhesive function

Mountford JK, Petitjean C, Putra HW, McCafferty JA, Setiabakti NM, Lee H, TØnnesen LL, McFadyen JD, Schoenwaelder SM, Eckly A, Gachet C, Ellis S, Voss AK, Dickins RA, Hamilton JR, Jackson SP

(2015), Nat Commun, 6, 6535

Current state and novel approaches of antiplatelet therapy

Metharom P, Berndt MC, Baker RI, Andrews RK

(2015), Arterioscler Thromb Vasc Biol, 35(6), 1327-38

The traumatic side of fibrinolysis

Medcalf RL

(2015), Blood, 125(16), 2457-8

Monosomal karyotype predicts inferior survival independently of a complex karyotype in patients with myelodysplastic syndromes

McQuilten ZK, Sundararajan V, Andrianopoulos N, Curtis DJ, Wood EM, Campbell LJ, Wall M

(2015), Cancer, 121(17), 2892-9

Platelets are not just for clots

McFadyen JD, Kaplan ZS

(2015), Transfus Med Rev, 29(2), 110-9

Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression

Martin A, Salvador F, Moreno-Bueno G, Floristán A, Ruiz-Herguido C, Cuevas EP, Morales S, Santos V, Csiszar K, Dubus P, Haigh JJ, Bigas A, Portillo F, Cano A

(2015), EMBO J, 34(8), 1090-109

14-3-3ζ coordinates adipogenesis of visceral fat

Lim GE, Albrecht T, Piske M, Sarai K, Lee JT, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD

(2015), Nat Commun, 6, 7671

NOX2 is critical for heterotypic neutrophil-platelet interactions during vascular inflammation

Kim K, Li J, Tseng A, Andrews RK, Cho J

(2015), Blood, 126(16), 1952-64

Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4

Kaplan ZS, Zarpellon A, Alwis I, Yuan Y, McFadyen J, Ghasemzadeh M, Schoenwaelder SM, Ruggeri ZM, Jackson SP

(2015), Nat Commun, 6, 7835

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

Horvay K, Jardé T, Casagranda F, Perreau VM, Haigh K, Nefzger CM, Akhtar R, Gridley T, Berx G, Haigh JJ, Barker N, Polo JM, Hime GR, Abud HE

(2015), EMBO J, 34(10), 1319-35

The dynamics of adult haematopoiesis in the bone and bone marrow environment

Ho MS, Medcalf RL, Livesey SA, Traianedes K

(2015), Br J Haematol, 170(4), 472-86

Particle generation, functionalization and sortase A-mediated modification with targeting of single-chain antibodies for diagnostic and therapeutic use

Hagemeyer CE, Alt K, Johnston AP, Such GK, Ta HT, Leung MK, Prabhu S, Wang X, Caruso F, Peter K

(2015), Nat Protoc, 10(1), 90-105

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