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Alfred Health research outcomes are published in a wide range of peer reviewed journals.
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Global regulator MorA affects virulence-associated protease secretion in Pseudomonas aeruginosa PAO1
Ravichandran A, Ramachandran M, Suriyanarayanan T, Wong CC, Swarup S
(2015), PLoS One, 10(4), e0123805
The platelet Fc receptor, FcγRIIa
Qiao J, Al-Tamimi M, Baker RI, Andrews RK, Gardiner EE
(2015), Immunol Rev, 268(1), 241-52
Methods to determine the lagrangian shear experienced by platelets during thrombus growth
Pinar IP, Arthur JF, Andrews RK, Gardiner EE, Ryan K, Carberry J
(2015), PLoS One, 10(12), e0144860
Discovery and SAR of novel pyrazolo[1,5-a]pyrimidines as inhibitors of CDK9
Phillipson LJ, Segal DH, Nero TL, Parker MW, Wan SS, de Silva M, Guthridge MA, Wei AH, Burns CJ
(2015), Bioorg Med Chem, 23(19), 6280-96
Asymmetric cell division during T cell development controls downstream fate
Pham K, Shimoni R, Charnley M, Ludford-Menting MJ, Hawkins ED, Ramsbottom K, Oliaro J, Izon D, Ting SB, Reynolds J, Lythe G, Molina-Paris C, Melichar H, Robey E, Humbert PO, Gu M, Russell SM
(2015), J Cell Biol, 210(6), 933-50
MYB elongation is regulated by the nucleic acid binding of NFΚB p50 to the intronic stem-loop region
Pereira LA, Hugo HJ, Malaterre J, Huiling X, Sonza S, Cures A, Purcell DF, Ramsland PA, Gerondakis S, Gonda TJ, Ramsay RG
(2015), PLoS One, 10(4), e0122919
Loss of c-REL but not NF-ΚB2 prevents autoimmune disease driven by FasL mutation
O'Reilly LA, Hughes P, Lin A, Waring P, Siebenlist U, Jain R, Gray DH, Gerondakis S, Strasser A
(2015), Cell Death Differ, 22(5), 767-78
Class II but not second class-prospects for the development of class II PI3K inhibitors
Mountford SJ, Zheng Z, Sundaram K, Jennings IG, Hamilton JR, Thompson PE
(2015), ACS Med Chem Lett, 6(1), 3-6
The class II PI 3-kinase, PI3KC2{alpha}, links platelet internal membrane structure to shear-dependent adhesive function
Mountford JK, Petitjean C, Putra HW, McCafferty JA, Setiabakti NM, Lee H, TØnnesen LL, McFadyen JD, Schoenwaelder SM, Eckly A, Gachet C, Ellis S, Voss AK, Dickins RA, Hamilton JR, Jackson SP
(2015), Nat Commun, 6, 6535
Current state and novel approaches of antiplatelet therapy
Metharom P, Berndt MC, Baker RI, Andrews RK
(2015), Arterioscler Thromb Vasc Biol, 35(6), 1327-38
The traumatic side of fibrinolysis
Medcalf RL
(2015), Blood, 125(16), 2457-8
Monosomal karyotype predicts inferior survival independently of a complex karyotype in patients with myelodysplastic syndromes
McQuilten ZK, Sundararajan V, Andrianopoulos N, Curtis DJ, Wood EM, Campbell LJ, Wall M
(2015), Cancer, 121(17), 2892-9
Platelets are not just for clots
McFadyen JD, Kaplan ZS
(2015), Transfus Med Rev, 29(2), 110-9
Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression
Martin A, Salvador F, Moreno-Bueno G, Floristán A, Ruiz-Herguido C, Cuevas EP, Morales S, Santos V, Csiszar K, Dubus P, Haigh JJ, Bigas A, Portillo F, Cano A
(2015), EMBO J, 34(8), 1090-109
14-3-3ζ coordinates adipogenesis of visceral fat
Lim GE, Albrecht T, Piske M, Sarai K, Lee JT, Ramshaw HS, Sinha S, Guthridge MA, Acker-Palmer A, Lopez AF, Clee SM, Nislow C, Johnson JD
(2015), Nat Commun, 6, 7671
NOX2 is critical for heterotypic neutrophil-platelet interactions during vascular inflammation
Kim K, Li J, Tseng A, Andrews RK, Cho J
(2015), Blood, 126(16), 1952-64
Thrombin-dependent intravascular leukocyte trafficking regulated by fibrin and the platelet receptors GPIb and PAR4
Kaplan ZS, Zarpellon A, Alwis I, Yuan Y, McFadyen J, Ghasemzadeh M, Schoenwaelder SM, Ruggeri ZM, Jackson SP
(2015), Nat Commun, 6, 7835
Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium
Horvay K, Jardé T, Casagranda F, Perreau VM, Haigh K, Nefzger CM, Akhtar R, Gridley T, Berx G, Haigh JJ, Barker N, Polo JM, Hime GR, Abud HE
(2015), EMBO J, 34(10), 1319-35
The dynamics of adult haematopoiesis in the bone and bone marrow environment
Ho MS, Medcalf RL, Livesey SA, Traianedes K
(2015), Br J Haematol, 170(4), 472-86
Particle generation, functionalization and sortase A-mediated modification with targeting of single-chain antibodies for diagnostic and therapeutic use
Hagemeyer CE, Alt K, Johnston AP, Such GK, Ta HT, Leung MK, Prabhu S, Wang X, Caruso F, Peter K
(2015), Nat Protoc, 10(1), 90-105