Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Planned withdrawal of dexamethasone after pomalidomide low-dose dexamethasone induction for lenalidomide-refractory multiple myeloma (ALLG MM14)

Kalff, Anna; Khong, Tiffany; Ramachandran, Malarmathy; Joy Ho, P; Mollee, Peter; D’Rozario, James; Taylor, Kerry; Estell, Jane; Norton, Sam; Kemp, Roslyn; Mitchell, Andrew J; Reynolds, John; Kennedy, Nola; Quach, Hang; Spencer, Andrew

(2022), HAEMATOLOGICA, 107(1), 321-325

DOI: 10.3324/haematol.2021.278655

Idiopathic upper extremity deep vein thrombosis: A systematic review

Yuen, Hiu Lam Agnes; Tan, Ee; Tran, Huyen; Chunilal, Sanjeev Daya

(2022), EUR J HAEMATOL, 109(5), 542-558

DOI: 10.1111/ejh.13842

Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia

So, Joan; Lewis, Alexander C; Smith, Lorey K; Stanley, Kym; Franich, Rheana; Yoannidis, David; Pijpers, Lizzy; Dominguez, Pilar; Hogg, Simon J; Vervoort, Stephin J; Brown, Fiona C; Johnstone, Ricky W; McDonald, Gabrielle; Ulanet, Danielle B; Murtie

(2022), EMBO MOL MED, 14(7), e15203

DOI: 10.15252/emmm.202115203

Mopping up crystals to keep the blood flowing

Hagemeyer, Christoph E

(2022), EBIOMEDICINE, 75, 103786

DOI: 10.1016/j.ebiom.2021.103786

Overall Hemostatic Potential Assay Detects Risk of Progression to Post-Thrombotic Syndrome in Anticoagulated Patients following Deep Vein Thrombosis

McLeod, Blake; Lim, Hui Yin; Nandurkar, Harshal; Ho, Prahlad; Wang, Julie

(2022), DIAGNOSTICS, 12(12), 3165

DOI: 10.3390/diagnostics12123165

SOHO State of the Art Updates and Next Questions | Mechanisms of Resistance to BCL2 Inhibitor Therapy in Chronic Lymphocytic Leukemia and Potential Future Therapeutic Directions

Bennett, Rory; Thompson, Ella; Tam, Constantine

(2022), CL LYMPH MYELOM LEUK, 22(11), 795-804

DOI: 10.1016/j.clml.2022.07.013

Template-Assisted Antibody Assembly: A Versatile Approach for Engineering Functional Antibody Nanoparticles

Hu, Yingjie; Li, Jianhua; Ju, Yi; Houston, Zachary H; Fletcher, Nicholas L; De Rose, Robert; Fernandes, Soraia; Hagemeyer, Christoph E; Alt, Karen; Thurecht, Kristofer J; Cortez-Jugo, Christina; Caruso, Frank

(2022), CHEM MATER, 34(8), 3694-3704

DOI: 10.1021/acs.chemmater.1c04397

Combination of Histone Deacetylase Inhibitor Panobinostat (LBH589) with ß-Catenin Inhibitor Tegavivint (BC2059) Exerts Significant Anti-Myeloma Activity Both In Vitro and In Vivo

Savvidou, Ioanna; Khong, Tiffany; Whish, Sophie; Carmichael, Irena; Sepehrizadeh, Tara; Mithraprabhu, Sridurga; Horrigan, Stephen K; de Veer, Michael; Spencer, Andrew

(2022), CANCERS, 14(3), 840

DOI: 10.3390/cancers14030840

Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death

Garciaz, Sylvain; Guirguis, Andrew A; Müller, Sebastian; Brown, Fiona C; Chan, Yih-Chih; Motazedian, Ali; Rowe, Caitlin L; Kuzich, James A; Chan, Kah Lok; Tran, Kevin; Smith, Lorey; MacPherson, Laura; Liddicoat, Brian; Lam, Enid YN; Cañeque, Tatiana

(2022), CANCER DISCOV, 12(3), 774-791

DOI: 10.1158/2159-8290.CD-21-0522

Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML

Salmon, Jessica M; Todorovski, Izabela; Stanley, Kym L; Bruedigam, Claudia; Kearney, Conor J; Martelotto, Luciano G; Rossello, Fernando; Semple, Timothy; Arnau, Gisela Mir; Zethoven, Magnus; Bots, Michael; Bjelosevic, Stefan; Cluse, Leonie A; Fraser,

(2022), CANCER DISCOV, 12(6), 1560-1579

DOI: 10.1158/2159-8290.CD-20-1145

Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses

Chan, Kah Lok; Gomez, Juliana; Cardinez, Chelisa; Kumari, Nishi; Sparbier, Christina E; Lam, Enid YN; Yeung, Miriam M; Garciaz, Sylvain; Kuzich, James A; Ong, Doen Ming; Brown, Fiona C; Chan, Yih-Chih; Vassiliadis, Dane; Wainwright, Elanor N; Motaz

(2022), CANCER CELL, 40(10), 1190-1206e9

DOI: 10.1016/j.ccell.2022.09.007

Ibrutinib use, treatment duration, and concomitant medications in Australian patients with relapsed or refractory chronic lymphocytic leukaemia

Mulligan, Stephen P; Opat, Stephen; Marlton, Paula; Kuss, Bryone; Gerungan, Poppy; Puig, Andrea; McGeachie, Marija; Tam, Constantine S

(2022), BRIT J HAEMATOL, 198(4), 790-793

DOI: 10.1111/bjh.18306

An extensional strain sensing mechanosome drives adhesion-independent platelet activation at supraphysiological hemodynamic gradients

Zainal Abidin, Nurul A; Poon, Eric KW; Szydzik, Crispin; Timofeeva, Mariia; Akbaridoust, Farzan; Brazilek, Rose J; Tovar Lopez, Francisco J; Ma, Xiao; Lav, Chitrarth; Marusic, Ivan; Thompson, Philip E; Mitchell, Arnan; Ooi, Andrew SH; Hamilton, Ju

(2022), BMC BIOL, 20(1), 73

DOI: 10.1186/s12915-022-01274-7

A novel ex vivo approach for measuring plasminogen activation upon established plasma clots

Palazzolo, Jason S; Medcalf, Robert L; Hagemeyer, Christoph E; Niego, Be'eri

(2022), RES PRACT THROMB HAE, 6(5),

DOI: 10.1002/rth2.12771

Age, sex and racial differences in fibrin formation and fibrinolysis within the healthy population

Wang, Julie; Lim, Hui Y; Nandurkar, Harshal; Ho, Prahlad

(2022), BLOOD COAGUL FIBRIN, 33(2), 141-144

DOI: 10.1097/MBC.0000000000001115

The Potential Role of Protease Systems in Hemophilic Arthropathy

Hauw, Wei Say Wayne; Chia, Joanne SJ; Nandurkar, Harshal H; Sashindranath, Maithili

(2022), BLOOD ADV, 6(18), 5505-5515

DOI: 10.1182/bloodadvances.2022007028

A novel flow cytometry procoagulant assay for diagnosis of vaccine-induced immune thrombotic thrombocytopenia

Lee, Christine SM; Liang, Hai Po Helena; Connor, David E; Dey, Agnibesh; Tohidi-Esfahani, Ibrahim; Campbell, Heather; Whittaker, Shane; Capraro, David; Favaloro, Emmanuel J; Donikian, Dea; Kondo, Mayuko; Hicks, Sarah M; Choi, Philip YI; Gardiner, E

(2022), BLOOD ADV, 6(11), 3494-3506

DOI: 10.1182/bloodadvances.2021006698

Neutrophil cathepsin G proteolysis of protease-activated receptor 4 generates a novel, functional tethered ligand

Stoller, Michelle L; Basak, Indranil; Denorme, Frederik; Rowley, Jesse W; Alsobrooks, James; Parsawar, Krishna; Nieman, Marvin T; Yost, Christian Con; Hamilton, Justin R; Bray, Paul F; Campbell, Robert A

(2022), BLOOD ADV, 6(7), 2303-2308

DOI: 10.1182/bloodadvances.2021006133

Microlyse: a thrombolytic agent that targets VWF for clearance of microvascular thrombosis

de Maat, Steven; Clark, Chantal C; Barendrecht, Arjan D; Smits, Simone; van Kleef, Nadine D; El Otmani, Hinde; Waning, Manon; van Moorsel, Marc; Szardenings, Michael; Delaroque, Nicolas; Vercruysse, Kristof; Urbanus, Rolf T; Sebastian, Silvie; Lenting

(2022), BLOOD, 139(4), 597-607

DOI: 10.1182/blood.2021011776

Self-Assembly of Oriented Antibody-Decorated Metal–Organic Framework Nanocrystals for Active-Targeting Applications

Alt, Karen; Carraro, Francesco; Jap, Edwina; Linares-Moreau, Mercedes; Riccò, Raffaele; Righetto, Marcello; Bogar, Marco; Amenitsch, Heinz; Hashad, Rania A; Doonan, Christian; Hagemeyer, Christoph E; Falcaro, Paolo

(2022), ADV MATER, 34(21), 2106607

DOI: 10.1002/adma.202106607

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