Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Traumatic brain injury opens blood-brain barrier to stealth liposomes via an enhanced permeability and retention (EPR)-like effect

Boyd BJ, Galle A, Daglas M, Rosenfeld JV, Medcalf R

(2015), J Drug Target, 23(9), 847-53

Extracorporeal membrane oxygenation-hemostatic complications

Murphy DA, Hockings LE, Andrews RK, Aubron C, Gardiner EE, Pellegrino VA, Davis AK

(2015), Transfus Med Rev, 29(2), 90-101

Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model

Brown FC, Conway AJ, Cerruti L, Collinge JE, McLean C, Wiley JS, Kile BT, Jane SM, Curtis DJ

(2015), Blood, 126(26), 2863-70

Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML

Rijal S, Fleming S, Cummings N, Rynkiewicz NK, Ooms LM, Nguyen NY, Teh TC, Avery S, McManus JF, Papenfuss AT, McLean C, Guthridge MA, Mitchell CA, Wei AH

(2015), Blood, 125(18), 2815-24

Approval of the first protease-activated receptor antagonist: rationale, development, significance, and considerations of a novel anti-platelet agent

French SL, Arthur JF, Tran HA, Hamilton JR

(2015), Blood Rev, 29(3), 179-89

R-CHOP with or without bevacizumab in patients with previously untreated diffuse large B-cell lymphoma: final MAIN study outcomes

Seymour JF, Pfreundschuh M, Trnĕný M, Sehn LH, Catalano J, Csinady E, Moore N, Coiffier B; MAIN Study Investigators

(2014), Haematologica, 99(8), 1343-9

Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies

Mesa RA, Kiladjian JJ, Verstovsek S, Al-Ali HK, Gotlib J, Gisslinger H, Levy R, Siulnik A, Gupta V, Khan M, DiPersio JF, McQuitty M, Catalano JV, Hunter DS, Knoops L, Deininger M, Cervantes F, Miller C, Vannucchi AM, Silver RT, Barbui T, Talpaz M, Barosi

(2014), Haematologica, 99(2), 292-8

Changing microbial epidemiology in hematopoietic stem cell transplant recipients: increasing resistance over a 9-year period

Macesic N, Morrissey CO, Cheng AC, Spencer A, Peleg AY

(2014), Transpl Infect Dis, 16(6), 887-96

A multicentre retrospective comparison of central nervous system prophylaxis strategies among patients with high-risk diffuse large B-cell lymphoma

Cheah CY, Herbert KE, O'Rourke K, Kennedy GA, George A, Fedele PL, Gilbertson M, Tan SY, Ritchie DS, Opat SS, Prince HM, Dickinson M, Burbury K, Wolf M, Januszewicz EH, Tam CS, Westerman DA, Carney DA, Harrison SJ, Seymour JF

(2014), Br J Cancer, 111(6), 1072-9

Lenalidomide and dexamethasone in transplant-ineligible patients with myeloma

Benboubker L, Dimopoulos MA, Dispenzieri A, Catalano J, Belch AR, Cavo M, Pinto A, Weisel K, Ludwig H, Bahlis N, Banos A, Tiab M, Delforge M, Cavenagh J, Geraldes C, Lee JJ, Chen C, Oriol A, de la Rubia J, Qiu L, White DJ, Binder D, Anderson K, Fermand JP

(2014), N Engl J Med, 371(10), 906-17

Consensus guidelines for the use of empiric and diagnostic-driven antifungal treatment strategies in haematological malignancy, 2014

Morrissey CO, Gilroy NM, Macesic N, Walker P, Ananda-Rajah M, May M, Heath CH, Grigg A, Bardy PG, Kwan J, Kirsa SW, Slavin M, Gottlieb T, Chen S

(2014), Intern Med J, 44(12b), 1298-314

The dual-specificity phosphatase 2 (DUSP2) does not regulate obesity-associated inflammation or insulin resistance in mice

Lancaster GI, Kraakman MJ, Kammoun HL, Langley KG, Estevez E, Banerjee A, Grumont RJ, Febbraio MA, Gerondakis S

(2014), PLoS One, 9(11), e111524

Lethal giant larvae 1 tumour suppressor activity is not conserved in models of mammalian T and B cell leukaemia

Hawkins ED, Oliaro J, Ramsbottom KM, Ting SB, Sacirbegovic F, Harvey M, Kinwell T, Ghysdael J, Johnstone RW, Humbert PO, Russell SM

(2014), PLoS One, 9(1), e87376

c-Rel regulates Ezh2 expression in activated lymphocytes and malignant lymphoid cells

Neo WH, Lim JF, Grumont R, Gerondakis S, Su IH

(2014), J Biol Chem, 289(46), 31693-707

Author reply

Wei A, Fleming S

(2014), Intern Med J, 44(8), 825

Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets

Wang X, Palasubramaniam J, Gkanatsas Y, Hohmann JD, Westein E, Kanojia R, Alt K, Huang D, Jia F, Ahrens I, Medcalf RL, Peter K, Hagemeyer CE

(2014), Circ Res, 114(7), 1083-93

The clonal evolution of leukemic stem cells in T-cell acute lymphoblastic leukemia

Tremblay CS, Curtis DJ

(2014), Curr Opin Hematol, 21(4), 320-5

New oral anticoagulants: a practical guide on prescription, laboratory testing and peri-procedural/bleeding management. Australasian Society of Thrombosis and Haemostasis

Tran H, Joseph J, Young L, McRae S, Curnow J, Nandurkar H, Wood P, McLintock C

(2014), Intern Med J, 44(6), 525-36

Species-Specific Regulation of t-PA and PAI-1 Gene Expression in Human and Rat Astrocytes

Tjärnlund-Wolf A, Hultman K, Blomstrand F, Nilsson M, Medcalf RL, Jern C

(2014), Gene Regul Syst Bio, 8, 113-8

ZEB2-transgene expression in the epidermis compromises the integrity of the epidermal barrier through the repression of different tight junction proteins

Tatari MN, De Craene B, Soen B, Taminau J, Vermassen P, Goossens S, Haigh K, Cazzola S, Lambert J, Huylebroeck D, Haigh JJ, Berx G

(2014), Cell Mol Life Sci, 71(18), 3599-609

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