Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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ADAMTS13 antibody depletion by bortezomib in thrombotic thrombocytopenic purpura

Shortt J, Oh DH, Opat SS

(2013), N Engl J Med, 368(1), 90-2

Plasminogen-stimulated inflammatory cytokine production by airway smooth muscle cells is regulated by annexin A2

Schuliga M, Langenbach S, Xia YC, Qin C, Mok JS, Harris T, Mackay GA, Medcalf RL, Stewart AG

(2013), Am J Respir Cell Mol Biol, 49(5), 751-8

The fusion partner specifies the oncogenic potential of NUP98 fusion proteins

Saw J, Curtis DJ, Hussey DJ, Dobrovic A, Aplan PD, Slape CI

(2013), Leuk Res, 37(12), 1668-73

Low adhesion receptor levels on circulating platelets in patients with lymphoproliferative diseases before receiving Navitoclax (ABT-263)

Qiao J, Schoenwaelder SM, Mason KD, Tran H, Davis AK, Kaplan ZS, Jackson SP, Kile BT, Andrews RK, Roberts AW, Gardiner EE

(2013), Blood, 121(8), 1479-81

Improved method for the preparation of a human cell-based, contact model of the blood-brain barrier

Niego B, Medcalf RL

(2013), J Vis Exp, 81, e50934

Histone deacetylase (HDAC) inhibitors as single agents induce multiple myeloma cell death principally through the inhibition of class I HDAC

Mithraprabhu S, Khong T, Jones SS, Spencer A

(2013), Br J Haematol, 162(4), 559-62

The p53 family and VEGF regulation: "it's complicated"

Farhang Ghahremani M, Goossens S, Haigh JJ

(2013), Cell Cycle, 12(9), 1331-2

Effect of ruxolitinib therapy on myelofibrosis-related symptoms and other patient-reported outcomes in COMFORT-I: a randomized, double-blind, placebo-controlled trial

Mesa RA, Gotlib J, Gupta V, Catalano JV, Deininger MW, Shields AL, Miller CB, Silver RT, Talpaz M, Winton EF, Harvey JH, Hare T, Erickson-Viitanen S, Sun W, Sandor V, Levy RS, Kantarjian HM, Verstovsek S

(2013), J Clin Oncol, 31(10), 1285-92

Differentiating haemostasis from thrombosis for therapeutic benefit

McFadyen JD, Jackson SP

(2013), Thromb Haemost, 110(5), 859-67

LIM-domain-only proteins in cancer

Matthews JM, Lester K, Joseph S, Curtis DJ

(2013), Nat Rev Cancer, 13(2), 111-22

Phosphorylation of serine 779 in fibroblast growth factor receptor 1 and 2 by protein kinase C(epsilon) regulates Ras/mitogen-activated protein kinase signaling and neuronal differentiation

Lonic A, Powell JA, Kong Y, Thomas D, Holien JK, Truong N, Parker MW, Guthridge MA

(2013), J Biol Chem, 288(21), 14874-85

Endothelial VEGF sculpts cortical cytoarchitecture

Li S, Haigh K, Haigh JJ, Vasudevan A

(2013), J Neurosci, 33(37), 14809-15

MEK inhibitors as a chemotherapeutic intervention in multiple myeloma

Chang-Yew Leow C, Gerondakis S, Spencer A

(2013), Blood Cancer J, 3, e105

The PAR1 antagonist, SCH79797, alters platelet morphology and function independently of PARs

Lee H, Hamilton JR

(2013), Thromb Haemost, 109(1), 164-7

Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein Ibα

Kruss S, Erpenbeck L, Amschler K, Mundinger TA, Boehm H, Helms HJ, Friede T, Andrews RK, Schön MP, Spatz JP

(2013), ACS Nano, 7(11), 9984-96

The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation

Krishna SM, Dear A, Craig JM, Norman PE, Golledge J

(2013), Atherosclerosis, 228(2), 295-305

The role of leukemia inhibitory factor in tubal ectopic pregnancy

Krishnan T, Winship A, Sonderegger S, Menkhorst E, Horne AW, Brown J, Zhang JG, Nicola NA, Tong S, Dimitriadis E

(2013), Placenta, 34(11), 1014-9

Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1

Huard CC, Tremblay CS, Helsper K, Delisle MC, Schindler D, Lévesque G, Carreau M

(2013), Blood, 121(10), 1729-39

Phase I pilot clinical trial of antenatal maternally administered melatonin to decrease the level of oxidative stress in human pregnancies affected by pre-eclampsia (PAMPR): study protocol

Hobson SR, Lim R, Gardiner EE, Alers NO, Wallace EM

(2013), BMJ Open, 3(9), e003788

Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein

Herold MJ, Rohrbeck L, Lang MJ, Grumont R, Gerondakis S, Tai L, Bouillet P, Kaufmann T, Strasser A

(2013), EMBO Rep, 14(11), 992-8

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