Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice

Qin CX, May LT, Li R, Cao N, Rosli S, Deo M, Alexander AE, Horlock D, Bourke JE, Yang YH, Stewart AG, Kaye DM, Du XJ, Sexton PM, Christopoulos A, Gao XM, Ritchie RH

(2017), Nat Commun, 8, 14232

DOI: 10.1038/ncomms14232

High-fiber diet and acetate supplementation change the gut microbiota and prevent the development of hypertension and heart failure in hypertensive mice

Marques FZ, Nelson E, Chu PY, Horlock D, Fiedler A, Ziemann M, Tan JK, Kuruppu S, Rajapakse NW, El-Osta A, Mackay CR, Kaye DM

(2017), Circulation, 135(10), 964-77

DOI: 10.1161/CIRCULATIONAHA.116.024545

Cardiac gene delivery using recirculating devices

Byrne MJ, Kaye DM

(2017), In: Ishikawa K (ed), Methods in Molecular Biology, volume 1521, Cardiac Gene Therapy: Methods and Protocols, Springer, Chapter 19, 261-9

Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling

Furtado MB, Wilmanns JC, Chandran A, Perera J, Hon O, Biben C, Willow TJ, Nim HT, Kaur G, Simonds S, Wu Q, Willians D, Salimova E, Plachta N, Denegre JM, Murray SA, Fatkin D, Cowley M, Pearson JT, Kaye D, Ramialison M, Harvey RP, Rosenthal NA, Costa MW

(2017), JCI Insight, 2(6), e88271

DOI: 10.1172/jci.insight.88271

Atrial fibrillation and heart failure - cause or effect?

Prabhu S, Voskoboinik A, Kaye DM, Kistler PM

(2017), Heart Lung Circ, 26(9), 967-74

DOI: 10.1016/j.hlc.2017.05.117

Catheter ablation versus medical rate control in atrial fibrillation and systolic dysfunction: the CAMERA-MRI study

Prabhu S, Taylor AJ, Costello BT, Kaye DM, McLellan AA, Voskoboinik A, Sugumar H, Lockwood SM, Stokes MB, Pathik B, Nalliah CJ, Wong GR, Azzopardi SM, Gutman S, Lee G, Layland J, Mariani JA, Ling LH, Kalman JM, Kistler PM

(2017), J Am Coll Cardiol, 70(16), 1949-61

DOI: 10.1016/j.jacc.2017.08.041

Impact of atrial fibrillation on rest and exercise haemodynamics in heart failure with mid-range and preserved ejection fraction

Kaye DM, Silvestry FE, Gustafsson F, Cleland JG, van Veldhuisen DJ, Ponikowski P, Komtebedde J, Nanayakkara S, Burkhoff D, Shah SJ

(2017), Eur J Heart Fail, 19(12), 1690-7

DOI: 10.1002/ejhf.930

A randomized double-blind trial of an interventional device treatment of functional mitral regurgitation in patients with symptomatic congestive heart failure-Trial design of the REDUCE FMR study

Goldberg SL, Meredith I, Marwick T, Haluska BA, Lipiecki J, Siminiak T, Mehta N, Kaye DM, Sievert H; REDUCE FMR Investigators

(2017), Am Heart J, 188, 167-74

DOI: 10.1016/j.ahj.2017.02.032

Hemodynamic profile of patients with heart failure and preserved ejection fraction vary by age

Nanayakkara S, Haykowsky M, Mariani J, Van Empel V, Maeder MT, Vizi D, Kaye DM

(2017), J Am Heart Assoc, 6(9), e005434

DOI: 10.1161/JAHA.116.005434

Extended release oral milrinone as an adjunct to heart failure therapy

Nanayakkara S, Bergin P, Mak V, Crannitch K, Kaye D

(2017), Intern Med J, 47(8), 973-4

DOI: 10.1111/imj.13503

Emerging therapies for heart failure with preserved ejection fraction

Nanayakkara S, Mariani J, Kaye D

(2017), Cardiol Today, 7, 26-8

Targets for heart failure with preserved ejection fraction

Nanayakkara S, Kaye DM

(2017), Clin Pharmacol Ther, 102, 228-37

DOI: 10.1002/cpt.723

Heart failure with preserved ejection fraction: improving diagnosis and management

Nanayakkara S, Mariani J, Kaye D

(2017), Med Today, 18(1), 37-42

Exercise hemodynamics as a predictor of myocardial recovery in LVAD patients

Segan L, Nanayakkara S, Leet A, Vizi D, Kaye DM

(2017), ASAIO J, 63(3), 342-5

DOI: 10.1097/MAT.0000000000000490

Outcomes of halo immobilization in the management of subaxial cervical facet fractures

Sime D, Gabbe B, Liew S

(2017), ANZ J Surg, 87(3), 159-64

DOI: 10.1111/ans.13656

Fracture fixation in the operative management of hip fractures (FAITH): an international, multicentre, randomised controlled trial

Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) Investigators

(2017), Lancet, 389(10078), 1519-27

DOI: 10.1016/S0140-6736(17)30066-1

Variation in prosthetic joint iInfection and treatment strategies during 4.5Üyears of follow-up after primary joint arthroplasty using administrative data of 41397 patients across Australian, European and United States hospitals

Marang-van de Mheen PJ, Bragan Turner E, Liew S, Mutalima N, Tran T, Rasmussen S, Nelissen RGHH, Gordon A

(2017), BMC Musculoskelet Disord, 18, 207

DOI: 10.1186/s12891-017-1569-2

Vitamin D use and health outcomes after surgery for hip fracture

Sprague S, Slobogean GP, Bogoch E, Petrisor B, Garibaldi A, O'Hara N, Bhandari M; FAITH Investigators

(2017), Orthopedics, 40(5), e868-75

DOI: 10.3928/01477447-20170907-01

Predictors of recovery in cyclists hospitalised for orthopaedic trauma following an on-road crash

Beck B, Ekegren CL, Cameron P, Edwards ER, Bucknill A, Judson R, Page R, Hau R, Stevenson M, Gabbe BJ

(2017), Accid Anal Prev, 106, 341-7

DOI: 10.1016/j.aap.2017.06.019

Twelve-month work-related outcomes following hip fracture in patients under 65 years of age

Ekegren CL, Edwards ER, Oppy A, Liew S, Page R, de Steiger R, Cameron PA, Bucknill A, Hau R, Gabbe BJ

(2017), Injury, 48(3), 701-7

DOI: 10.1016/j.injury.2017.01.033

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