Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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AKT Isoforms 1 and 3 regulate basal and epidermal growth factor-stimulated SGHPL-5 trophoblast cell migration in humans

Haslinger P, Haider S, Sonderegger S, Otten JV, Pollheimer J, Whitley G, Knöfler M

(2013), Biol Reprod, 88(3), 54

The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma samples

Hapgood G, Butler J, Malan E, Chunilal S, Tran H

(2013), Thromb Haemost, 110(2), 308-15

Efficient ROSA26-based conditional and/or inducible transgenesis using RMCE-compatible F1 hybrid mouse embryonic stem cells

Haenebalcke L, Goossens S, Naessens M, Kruse N, Farhang Ghahremani M, Bartunkova S, Haigh K, Pieters T, Dierickx P, Drogat B, Nyabi O, Wirth D, Haigh JJ

(2013), Stem Cell Rev Rep, 9(6), 774-85

Rituximab is associated with improved survival for aggressive B cell CNS lymphoma

Gregory G, Arumugaswamy A, Leung T, Chan KL, Abikhair M, Tam C, Bajel A, Cher L, Grigg A, Ritchie D, Opat S

(2013), Neuro Oncol, 15(8), 1068-73

Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations

Green BD, Jabbour AM, Sandow JJ, Riffkin CD, Masouras D, Daunt CP, Salmanidis M, Brumatti G, Hemmings BA, Guthridge MA, Pearson RB, Ekert PG

(2013), Cell Death Differ, 20(10), 1341-9

The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi

Ghasemzadeh M, Kaplan ZS, Alwis I, Schoenwaelder SM, Ashworth KJ, Westein E, Hosseini E, Salem HH, Slattery R, McColl SR, Hickey MJ, Ruggeri ZM, Yuan Y, Jackson SP

(2013), Blood, 121(22), 4555-66

Platelet-leukocyte crosstalk: linking proinflammatory responses to procoagulant state

Ghasemzadeh M, Hosseini E

(2013), Thromb Res, 131(3), 191-7

Platelets: envoys at the infection frontline

Gardiner EE, Andrews RK

(2013), J Infect Dis, 208(6), 871-3

The challenges of measuring bleeding outcomes in clinical trials of platelet transfusions

Estcourt LJ, Heddle N, Kaufman R, McCullough J, Murphy MF, Slichter S, Wood EM, Stanworth SJ; Biomedical Excellence for Safer Transfusion Collaborative

(2013), Transfusion, 53(7), 1531-43

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

Costa M, Sourris K, Lim SM, Yu QC, Hirst CE, Parkington HC, Jokubaitis VJ, Dear AE, Liu HB, Micallef SJ, Koutsis K, Elefanty AG, Stanley EG

(2013), Stem Cell Res, 10(1), 103-17

Safety of withholding anticoagulation in pregnant women with suspected deep vein thrombosis following negative serial compression ultrasound and iliac vein imaging

Chan WS, Spencer FA, Lee AY, Chunilal S, Douketis JD, Rodger M, Ginsberg JS

(2013), CMAJ, 185(4), E194-200

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

Cellot S, Hope KJ, Chagraoui J, Sauvageau M, Deneault É, MacRae T, Mayotte N, Wilhelm BT, Landry JR, Ting SB, Krosl J, Humphries K, Thompson A, Sauvageau G

(2013), Blood, 122(9), 1545-55

Oncogenic mutations of p110α isoform of PI 3-kinase upregulate its protein kinase activity

Buchanan CM, Dickson JM, Lee WJ, Guthridge MA, Kendall JD, Shepherd PR

(2013), PLoS One, 8(8), e71337

ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level

Brown FC, Scott N, Rank G, Collinge JE, Vadolas J, Vickaryous N, Whitelaw N, Whitelaw E, Kile BT, Jane SM, Curtis DJ

(2013), Blood Cells Mol Dis, 50(2), 86-92

A single-arm, phase II study of the anti-Blys monoclonal antibody belimumab in symptomatic Waldenstrom macroglobulinemia

Bishton M, Spencer A, Dickinson M, Ritchie D

(2013), Clin Lymphoma Myeloma Leuk, 13(5), 575-8

Histone deacetylase inhibitors reduce glycoprotein VI expression and platelet responses to collagen related peptide

Bishton MJ, Gardiner EE, Harrison SJ, Prince HM, Johnstone RW

(2013), Thromb Res, 131(6), 514-20

Platelet hem-immunoreceptor tyrosine-based activation motif receptors: at least one required

Berndt MC, Andrews RK

(2013), Arterioscler Thromb Vasc Biol, 33(5), 884-5

Platelet transport rates and binding kinetics at high shear over a thrombus

Bark DL Jr, Ku DN

(2013), Biophys J, 105(2), 502-11

Exacerbation of glycoprotein VI-dependent platelet responses in a rhesus monkey model of type 1 diabetes

Arthur JF, Shen Y, Chen Y, Qiao J, Ni R, Lu Y, Andrews RK, Gardiner EE, Cheng J

(2013), J Diabetes Res, 2013, 370212

Bernard-Soulier syndrome: an update

Andrews RK, Berndt MC

(2013), Semin Thromb Hemost, 39(6), 656-62

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