Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait

Cops EJ, Sashindranath M, Daglas M, Short KM, da Fonseca Pereira C, Pang TY, Lijnen RH, Smyth IM, Hannan AJ, Samson AL, Medcalf RL

(2013), Exp Neurol, 249, 8-19

Limitations of targeted therapy with sorafenib in elderly high-risk myelodysplastic syndrome and acute myeloid leukemia

Wei A, Tan P

(2013), Leuk Lymphoma, 54(4), 675-6

GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations

Perugini M, Iarossi DG, Kok CH, Cummings N, Diakiw SM, Brown AL, Danner S, Bardy P, Bik To L, Wei AH, Lewis ID, D'Andrea RJ

(2013), Leukemia, 27(7), 1588-92

High-dose cytarabine (24 g/m2) in combination with idarubicin (HiDAC-3) results in high first-cycle response with limited gastrointestinal toxicity in adult acute myeloid leukaemia

Low M, Lee D, Coutsouvelis J, Patil S, Opat S, Walker P, Schwarer A, Salem H, Avery S, Spencer A, Wei A

(2013), Intern Med J, 43(3), 294-7

Fludarabine, cytarabine, granulocyte-colony stimulating factor and amsacrine: an effective salvage therapy option for acute myeloid leukemia at first relapse

Fong CY, Grigoriadis G, Hocking J, Coutsouvelis J, Muirhead J, Campbell P, Paul E, Walker P, Avery S, Patil S, Spencer A, Schwarer A, Wei A

(2013), Leuk Lymphoma, 54(2), 336-41

Effectiveness of a single fixed dose of rasburicase 3 mg in the management of tumour lysis syndrome

Coutsouvelis J, Wiseman M, Hui L, Poole S, Dooley M, Patil S, Avery S, Wei A, Spencer A

(2013), Br J Clin Pharmacol, 75(2), 550-3

Two missense mutations identified in venous thrombosis patients impair the inhibitory function of the protein Z dependent protease inhibitor

Young LK, Birch NP, Browett PJ, Coughlin PB, Horvath AJ, Van de Water NS, Ockelford PA, Harper PL

(2012), Thromb Haemost, 107(5), 854-63

How to manage neutropenia in multiple myeloma

Palumbo A, Bladé J, Boccadoro M, Palladino C, Davies F, Dimopoulos M, Dmoszynska A, Einsele H, Moreau P, Sezer O, Spencer A, Sonneveld P, San Miguel J

(2012), Clin Lymphoma Myeloma Leuk, 12(1), 5-11

MyelomA Genetics International Consortium

Morgan G, Johnsen HE, Goldschmidt H, Palumbo A, Cavo M, Sonneveld P, Miguel JS, Chim CS, Browne P, Einsele H, Waage A, Turesson I, Spencer A, Hajek R, Ludwig H, Hemminki K, Houlston R

(2012), Leuk Lymphoma, 53(5), 796-800

Validation of whole blood impedance aggregometry as a new diagnostic tool for HIT: results of a large Australian study

Morel-Kopp MC, Tan CW, Brighton TA, McRae S, Baker R, Tran H, Mollee P, Kershaw G, Joseph J, Ward C; ASTH Clinical Trials Group

(2012), Thromb Haemost, 107(3), 575-83

Recommendations for the prevention of pregnancy-associated venous thromboembolism

McLintock C, Brighton T, Chunilal S, Dekker G, McDonnell N, McRae S, Muller P, Tran H, Walters BN, Young L; Councils of the Society of Obstetric Medicine of Australia and New Zealand; Australasian Society of Thrombosis and Haemostasis

(2012), Aust N Z J Obstet Gynaecol, 52(1), 3-13

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function

Mazharian A, Wang YJ, Mori J, Bem D, Finney B, Heising S, Gissen P, White JG, Berndt MC, Gardiner EE, Nieswandt B, Douglas MR, Campbell RD, Watson SP, Senis YA

(2012), Sci Signal, 5(248), ra78

Overcoming aspirin treatment failure in diabetes

Linden MD, Tran HA

(2012), Crit Rev Clin Lab Sci, 49(5-6), 183-98

Antithrombotic phosphoinositide 3-kinase β inhibitors in humans: a 'shear' delight!

Jackson SP, Schoenwaelder SM

(2012), J Thromb Haemost, 10(10), 2123-6

c-Rel: shaping CD4 regulatory T cell development in unexpected ways

Gerondakis S, Fulford T, Grumont RJ

(2012), Transcription, 3(5), 245-9

Neutrophil extracellular traps (NETs) and infection-related vascular dysfunction

Gardiner EE, Andrews RK

(2012), Blood Rev, 26(6), 255-9

Regulation of delta-aminolevulinic acid dehydratase by krüppel-like factor 1

Desgardin AD, Abramova T, Rosanwo TO, Kartha S, Shim EH, Jane SM, Cunningham JM

(2012), PLoS One, 7(10), e46482

MDS with del(5q) and associated cKIT D816V positive mastocytosis

Chan N, Tan SY, Opat S, Shortt J

(2012), Pathology, 44(5), 492-3

Peptide nucleic acid monomers: a convenient and efficient synthetic approach to Fmoc/Boc monomers

Browne EC, Langford SJ, Abbott BM

(2012), Aust J Chem, 65(5), 539-44

How we use recombinant activated Factor VII in patients with haemophilia A or B complicated by inhibitors

Brown SA, Barnes C, Curtin J, Dunkley S, Ockelford P, Phillips J, Rowell J, Smith M, Tran H

(2012), Intern Med J, 42(11), 1243-50