Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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MEK inhibitors as a chemotherapeutic intervention in multiple myeloma

Chang-Yew Leow C, Gerondakis S, Spencer A

(2013), Blood Cancer J, 3, e105

The PAR1 antagonist, SCH79797, alters platelet morphology and function independently of PARs

Lee H, Hamilton JR

(2013), Thromb Haemost, 109(1), 164-7

Adhesion maturation of neutrophils on nanoscopically presented platelet glycoprotein Ibα

Kruss S, Erpenbeck L, Amschler K, Mundinger TA, Boehm H, Helms HJ, Friede T, Andrews RK, Schön MP, Spatz JP

(2013), ACS Nano, 7(11), 9984-96

The potential role of homocysteine mediated DNA methylation and associated epigenetic changes in abdominal aortic aneurysm formation

Krishna SM, Dear A, Craig JM, Norman PE, Golledge J

(2013), Atherosclerosis, 228(2), 295-305

The role of leukemia inhibitory factor in tubal ectopic pregnancy

Krishnan T, Winship A, Sonderegger S, Menkhorst E, Horne AW, Brown J, Zhang JG, Nicola NA, Tong S, Dimitriadis E

(2013), Placenta, 34(11), 1014-9

Fanconi anemia proteins interact with CtBP1 and modulate the expression of the Wnt antagonist Dickkopf-1

Huard CC, Tremblay CS, Helsper K, Delisle MC, Schindler D, Lévesque G, Carreau M

(2013), Blood, 121(10), 1729-39

Phase I pilot clinical trial of antenatal maternally administered melatonin to decrease the level of oxidative stress in human pregnancies affected by pre-eclampsia (PAMPR): study protocol

Hobson SR, Lim R, Gardiner EE, Alers NO, Wallace EM

(2013), BMJ Open, 3(9), e003788

Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein

Herold MJ, Rohrbeck L, Lang MJ, Grumont R, Gerondakis S, Tai L, Bouillet P, Kaufmann T, Strasser A

(2013), EMBO Rep, 14(11), 992-8

AKT Isoforms 1 and 3 regulate basal and epidermal growth factor-stimulated SGHPL-5 trophoblast cell migration in humans

Haslinger P, Haider S, Sonderegger S, Otten JV, Pollheimer J, Whitley G, Knöfler M

(2013), Biol Reprod, 88(3), 54

The effect of dabigatran on the activated partial thromboplastin time and thrombin time as determined by the Hemoclot thrombin inhibitor assay in patient plasma samples

Hapgood G, Butler J, Malan E, Chunilal S, Tran H

(2013), Thromb Haemost, 110(2), 308-15

Efficient ROSA26-based conditional and/or inducible transgenesis using RMCE-compatible F1 hybrid mouse embryonic stem cells

Haenebalcke L, Goossens S, Naessens M, Kruse N, Farhang Ghahremani M, Bartunkova S, Haigh K, Pieters T, Dierickx P, Drogat B, Nyabi O, Wirth D, Haigh JJ

(2013), Stem Cell Rev Rep, 9(6), 774-85

Rituximab is associated with improved survival for aggressive B cell CNS lymphoma

Gregory G, Arumugaswamy A, Leung T, Chan KL, Abikhair M, Tam C, Bajel A, Cher L, Grigg A, Ritchie D, Opat S

(2013), Neuro Oncol, 15(8), 1068-73

Akt1 is the principal Akt isoform regulating apoptosis in limiting cytokine concentrations

Green BD, Jabbour AM, Sandow JJ, Riffkin CD, Masouras D, Daunt CP, Salmanidis M, Brumatti G, Hemmings BA, Guthridge MA, Pearson RB, Ekert PG

(2013), Cell Death Differ, 20(10), 1341-9

The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi

Ghasemzadeh M, Kaplan ZS, Alwis I, Schoenwaelder SM, Ashworth KJ, Westein E, Hosseini E, Salem HH, Slattery R, McColl SR, Hickey MJ, Ruggeri ZM, Yuan Y, Jackson SP

(2013), Blood, 121(22), 4555-66

Platelet-leukocyte crosstalk: linking proinflammatory responses to procoagulant state

Ghasemzadeh M, Hosseini E

(2013), Thromb Res, 131(3), 191-7

Platelets: envoys at the infection frontline

Gardiner EE, Andrews RK

(2013), J Infect Dis, 208(6), 871-3

The challenges of measuring bleeding outcomes in clinical trials of platelet transfusions

Estcourt LJ, Heddle N, Kaufman R, McCullough J, Murphy MF, Slichter S, Wood EM, Stanworth SJ; Biomedical Excellence for Safer Transfusion Collaborative

(2013), Transfusion, 53(7), 1531-43

Derivation of endothelial cells from human embryonic stem cells in fully defined medium enables identification of lysophosphatidic acid and platelet activating factor as regulators of eNOS localization

Costa M, Sourris K, Lim SM, Yu QC, Hirst CE, Parkington HC, Jokubaitis VJ, Dear AE, Liu HB, Micallef SJ, Koutsis K, Elefanty AG, Stanley EG

(2013), Stem Cell Res, 10(1), 103-17

Safety of withholding anticoagulation in pregnant women with suspected deep vein thrombosis following negative serial compression ultrasound and iliac vein imaging

Chan WS, Spencer FA, Lee AY, Chunilal S, Douketis JD, Rodger M, Ginsberg JS

(2013), CMAJ, 185(4), E194-200

RNAi screen identifies Jarid1b as a major regulator of mouse HSC activity

Cellot S, Hope KJ, Chagraoui J, Sauvageau M, Deneault É, MacRae T, Mayotte N, Wilhelm BT, Landry JR, Ting SB, Krosl J, Humphries K, Thompson A, Sauvageau G

(2013), Blood, 122(9), 1545-55

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