Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Oncogenic mutations of p110α isoform of PI 3-kinase upregulate its protein kinase activity

Buchanan CM, Dickson JM, Lee WJ, Guthridge MA, Kendall JD, Shepherd PR

(2013), PLoS One, 8(8), e71337

ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level

Brown FC, Scott N, Rank G, Collinge JE, Vadolas J, Vickaryous N, Whitelaw N, Whitelaw E, Kile BT, Jane SM, Curtis DJ

(2013), Blood Cells Mol Dis, 50(2), 86-92

A single-arm, phase II study of the anti-Blys monoclonal antibody belimumab in symptomatic Waldenstrom macroglobulinemia

Bishton M, Spencer A, Dickinson M, Ritchie D

(2013), Clin Lymphoma Myeloma Leuk, 13(5), 575-8

Histone deacetylase inhibitors reduce glycoprotein VI expression and platelet responses to collagen related peptide

Bishton MJ, Gardiner EE, Harrison SJ, Prince HM, Johnstone RW

(2013), Thromb Res, 131(6), 514-20

Platelet hem-immunoreceptor tyrosine-based activation motif receptors: at least one required

Berndt MC, Andrews RK

(2013), Arterioscler Thromb Vasc Biol, 33(5), 884-5

Platelet transport rates and binding kinetics at high shear over a thrombus

Bark DL Jr, Ku DN

(2013), Biophys J, 105(2), 502-11

Exacerbation of glycoprotein VI-dependent platelet responses in a rhesus monkey model of type 1 diabetes

Arthur JF, Shen Y, Chen Y, Qiao J, Ni R, Lu Y, Andrews RK, Gardiner EE, Cheng J

(2013), J Diabetes Res, 2013, 370212

Bernard-Soulier syndrome: an update

Andrews RK, Berndt MC

(2013), Semin Thromb Hemost, 39(6), 656-62

Factor XIII assays

Opat S, Butler J, Malan E, Duncan E, Tran HA

(2013), In: Monagle P (ed), Haemostasis: Methods and Protocols, Methods in Molecular Biology, Volume 992, Humana Press, Springer, USA, Chapter 13, 171-80

A multimode-TIRFM and microfluidic technique to examine platelet adhesion dynamics

Nesbitt WS, Tovar-Lopez FJ, Westein E, Harper IS, Jackson SP

(2013), In: Coutts AS (ed), Adhesion Protein Protocols, Methods in Molecular Biology, Volume 1046, Humana Press, Springer, USA, Chapter 3, 39-58

Cre/loxP - Transgenics

Haenebalcke L, Haigh J

(2013), In: Maloy S, Hughes K (eds), Brenner's Encyclopedia of Genetics, Academic Press Elsevier, USA, 212-7

Platelet thrombus formation in flowing blood

Ruggeri ZM, Jackson S

(2013), In: Michelson AD (ed), Platelets, Academic Press Elsevier, UK, Chapter 20, 399-423

The GPIb-IX-V complex

Andrews RK, Berndt MC

(2013), In: Michelson AD (ed), Platelets, Academic Press Elsevier, UK, Chapter 10, 195-213

Mocarhagin

Andrews RK, Berndt MC

(2013), In: Rawlings ND, Salvesen GS (eds), Handbook of Proteolytic Enzymes, 3rd edition, Academic Press Elsevier, UK, 1073-5

Cytomegalovirus in pregnancy: to screen or not to screen

Walker SP, Palma-Dias R, Wood EM, Shekleton P, Giles ML

(2013), BMC Pregnancy Childbirth, 13, 96

Improving the transition of highly complex patients into the community: impact of a pharmacist in an allogeneic stem cell transplant (SCT) outpatient clinic

Chieng R, Coutsouvelis J, Poole S, Dooley MJ, Booth D, Wei A

(2013), Support Care Cancer, 21(12), 3491-5

Discovery of potent and selective benzothiazole hydrazone inhibitors of Bcl-XL

Sleebs BE, Kersten WJ, Kulasegaram S, Nikolakopoulos G, Hatzis E, Moss RM, Parisot JP, Yang H, Czabotar PE, Fairlie WD, Lee EF, Adams JM, Chen L, van Delft MF, Lowes KN, Wei A, Huang DC, Colman PM, Street IP, Baell JB, Watson K, Lessene G

(2013), J Med Chem, 56(13), 5514-40

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription

Thomas D, Powell JA, Vergez F, Segal DH, Nguyen NY, Baker A, Teh TC, Barry EF, Sarry JE, Lee EM, Nero TL, Jabbour AM, Pomilio G, Green BD, Manenti S, Glaser SP, Parker MW, Lopez AF, Ekert PG, Lock RB, Huang DC, Nilsson SK, Récher C, Wei AH, Guthridge MA

(2013), Blood, 122(5), 738-48

Utility of a clinical risk score to identify high-risk patients with de novo acute myeloid leukaemia in first remission after high-dose cytarabine (HiDAC) based induction chemotherapy

Ling V, Burnett AK, Bradstock K, Seymour JF, Hills RK, Wei A

(2013), Br J Haematol, 160(6), 861-3

Methylation of KLF5 contributes to reduced expression in acute myeloid leukaemia and is associated with poor overall survival

Diakiw SM, Perugini M, Kok CH, Engler GA, Cummings N, To LB, Wei AH, Lewis ID, Brown AL, D'Andrea RJ

(2013), Br J Haematol, 161(6), 884-8

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