Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Polyphenol-Functionalized Cubosomes as Thrombolytic Drug Carriers

Yu, Haitao; Palazzolo, Jason S; Ju, Yi; Niego, Be'eri; Pan, Shuaijun; Hagemeyer, Christoph E; Caruso, Frank

(2022), ADV HEALTHC MATER, 11(21), 2201151

DOI: 10.1002/adhm.202201151

Alcohol use in the year following approach bias modification during inpatient withdrawal: secondary outcomes from a double-blind, multi-site randomized controlled trial

Manning, Victoria; Garfield, Joshua BB; Reynolds, John; Staiger, Petra K; Piercy, Hugh; Bonomo, Yvonne; Lloyd-Jones, Martyn; Jacka, David; Wiers, Reinout W; Verdejo-Garcia, Antonio; Lubman, Dan I

(2022), ADDICTION, 117(11), 2837-2846

DOI: 10.1111/add.15989

Bioresponsive Polyphenol-Based Nanoparticles as Thrombolytic Drug Carriers

Yu, Haitao; Palazzolo, Jason S; Zhou, Jiajing; Hu, Yingjie; Niego, Be'Eri; Pan, Shuaijun; Ju, Yi; Wang, Ting Yi; Lin, Zhixing; Hagemeyer, Christoph E; Caruso, Frank

(2022), ACS APPL MATER INTER, 14(3), 3740-3751

DOI: 10.1021/acsami.1c19820

Pulmonary embolus

Dix, Caroline; Tran, Huyen

(2022), AUST J GEN PRACT, 51(9), 667-671

DOI: 10.31128/AJGP-05-22-6440

Identification of a Distinct Platelet Phenotype in the Elderly: ADP Hypersensitivity Coexists With Platelet PAR (Protease-Activated Receptor)-1 and PAR-4-Mediated Thrombin Resistance

Gnanenthiran, Sonali R; Pennings, Gabrielle J; Reddel, Caroline J; Campbell, Heather; Kockx, Maaike; Hamilton, Justin R; Chen, Vivien M; Kritharides, Leonard

(2022), ARTERIOSCL THROM VAS, 42(8), 960-972

DOI: 10.1161/ATVBAHA.120.316772

Tranexamic acid alters the immunophenotype of phagocytes after lower limb surgery

Draxler DF, Hanafi G, Zahra S, McCutcheon F, Ho H, Keragala CB, Liu Z, Daly D, Painter T, Wallace S, Plebanski M, Myles PS, Medcalf RL

(2022), Thromb J, 20(1), 17

DOI: 10.1186/s12959-022-00373-3

Characterisation of Plasma Mitochondrial DNA, MMP-9 and Neutrophil Elastase in Patients Undergoing Coronary Artery Bypass Grafting: Effects of Tranexamic Acid and Postoperative Pneumonia

Sandler N, Ho H, Draxler DF, Bain CR, Smith JA, Hauser CJ, Gruen RL, Myles PS, Medcalf RL

(2022), Heart Lung Circ, 31(3), 439-46

DOI: 10.1016/j.hlc.2021.08.008

Palifermin, administered for three doses only, reduces mucositis in patients undergoing HSCT and receiving chemoradiotherapy conditioning

Coutsouvelis J, Dooley M, Kirkpatrick CM, Avery S, Hopkins R, Spencer A

(2022), BONE MARROW TRANSPL, 57(8), 1329-31

DOI: 10.1038/s41409-022-01714-6

Receiving four or fewer cycles of therapy predicts poor survival in newly diagnosed transplant-ineligible patients with myeloma who are treated with bortezomib-based induction

Boyle, Stephen; Wellard, Cameron; Moore, Elizabeth M.; Blacklock, Hilary; Harrison, Simon J.; Ho, Phoebe Joy; Hocking, Jay; McQuilten, Zoe K.; Quach, Hang; Spearing, Ruth; Wood, Erica M.; Spencer, Andrew; Mollee, Peter; ,

(2021), EUR J HAEMATOL, 107(4), 497-499

DOI: 10.1111/ejh.13677

TOP2A expression predicts responsiveness to carfilzomib in myeloma and informs novel combinatorial strategies for enhanced proteasome inhibitor cell killing

Reale, Antonia; Khong, Tiffany; Mithraprabhu, Sridurga; Savvidou, Ioanna; Hocking, Jay John; Bergin, Krystal Frances; Ramachandran, Malarmathy; Chen, Maoshan; Dammacco, Francesco; Ria, Roberto; Silvestris, Francesco; Vacca, Angelo; Reynolds, John; Spencer

(2021), LEUKEMIA LYMPHOMA, 62(2), 337-347

DOI: 10.1080/10428194.2020.1832659

Estimating the Productivity Impact of Acute Myeloid Leukemia in Australia Between 2020 and 2029, Using a Novel Work Utility Measure

Parker, Catriona; Liew, Danny; Ademi, Zanfina; Owen, Alice; Ayton, Darshini R; Wei, Andrew H.; Zomer, Ella

(2021), JCO ONCOL PRACT, 17(11), E1803-E1810

DOI: 10.1200/OP.20.00904

The Myeloma Landscape in Australia and New Zealand: The First 8 Years of the Myeloma and Related Diseases Registry (MRDR)

Bergin, Krystal; Wellard, Cameron; Moore, Elizabeth; McQuilten, Zoe; Blacklock, Hilary; Harrison, Simon J.; Ho, P. Joy; King, Tracy; Quach, Hang; Mollee, Peter; Walker, Patricia; Wood, Erica; Spencer, Andrew; ,

(2021), CL LYMPH MYELOM LEUK, 21(6), e510-e520

DOI: 10.1016/j.clml.2021.01.016

Real-world utilisation of ASCT in multiple myeloma (MM)

Bergin, Krystal; Wellard, Cameron; Augustson, Bradley; Cooke, Rachel; Blacklock, Hilary; Harrison, Simon J.; Ho, Joy; King, Tracy; Quach, Hang; Mollee, Peter; Walker, Patricia; Moore, Elizabeth; McQuilten, Zoe; Wood, Erica; Spencer, Andrew; ,

(2021), BONE MARROW TRANSPL, 56(10), 2533-2543

DOI: 10.1038/s41409-021-01308-8

Induction of muscle-regenerative multipotent stem cells from human adipocytes by PDGF-AB and 5-azacytidine

Yeola, Avani; Subramanian, Shruthi; Oliver, Rema A.; Lucas, Christine A.; Thoms, Julie A.I.; Yan, Feng; Olivier, Jake; Chacon, Diego; Tursky, Melinda L.; Srivastava, Pallavi; Potas, Jason R.; Hung, Tzongtyng; Power, Carl; Hardy, Philip; Ma, David D.; Kili

(2021), SCI ADV, 7(3), eabd1929

DOI: 10.1126/sciadv.abd1929

Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity

Wang, Jueqiong; Farkas, Carlos; Benyoucef, Aissa; Carmichael, Catherine; Haigh, Katharina; Wong, Nick; Huylebroeck, Danny; Stemmler, Marc P.; Brabletz, Simone; Brabletz, Thomas; Nefzger, Christian M.; Goossens, Steven; Berx, Geert; Polo, Jose M.; Haigh, J

(2021), PLOS BIOL, 19(9), e3001394

DOI: 10.1371/journal.pbio.3001394

MOMENTUM: momelotinib vs danazol in patients with myelofibrosis previously treated with JAKi who are symptomatic and anemic

Verstovsek, Srdan; Chen, Chih Cheng; Egyed, Miklós; Ellis, Martin; Fox, Laura; Goh, Yeow T.; Gupta, Vikas; Harrison, Claire; Kiladjian, Jean Jacques; Lazaroiu, Mihaela C.; Mead, Adam; McLornan, Donal; McMullin, Mary F.; Oh, Stephen T.; Perkins, Andrew; Pl

(2021), FUTURE ONCOL, 17(12), 1449-1458

DOI: 10.2217/fon-2020-1048

Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia

Van Thillo, Quentin; De Bie, Jolien; Seneviratne, Janith A.; Demeyer, Sofie; Omari, Sofia; Balachandran, Anushree; Zhai, Vicki; Tam, Wai L.; Sweron, Bram; Geerdens, Ellen; Gielen, Olga; Provost, Sarah; Segers, Heidi; Boeckx, Nancy; Marshall, Glenn M.; Che

(2021), NAT COMMUN, 12(1), 4164

DOI: 10.1038/s41467-021-24442-9

Shutting the gate: targeting endocytosis in acute leukemia

Tremblay, Cedric S.; Ting, Stephen B.; McCluskey, Adam; Robinson, Phillip J.; Curtis, David J.

(2021), EXP HEMATOL, 104, 17-31

DOI: 10.1016/j.exphem.2021.09.003

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Thijssen, Rachel; Diepstraten, Sarah T.; Moujalled, Donia; Chew, Edward; Flensburg, Christoffer; Shi, Melissa X.; Dengler, Michael A.; Litalien, Veronique; MacRaild, Sarah; Chen, Maoshan; Anstee, Natasha S.; Reljić, Boris; Gabriel, Sarah S.; Djajawi, Tirt

(2021), BLOOD, 137(20), 2721-2735

DOI: 10.1182/blood.2020010167

Transglutaminase-2, RNA-binding proteins and mitochondrial proteins selectively traffic to MDCK cell-derived microvesicles following H-Ras-induced epithelial–mesenchymal transition

Shafiq, Adnan; Suwakulsiri, Wittaya; Rai, Alin; Chen, Maoshan; Greening, David W.; Zhu, Hong Jian; Xu, Rong; Simpson, Richard J.

(2021), PROTEOMICS, 21(13-14), 2000221

DOI: 10.1002/pmic.202000221