Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival

Thomas D, Powell JA, Green BD, Barry EF, Ma Y, Woodcock J, Fitter S, Zannettino AC, Pitson SM, Hughes TP, Lopez AF, Shepherd PR, Wei AH, Ekert PG, Guthridge MA

(2013), PLoS Biol, 11(3), e1001515

Stage I of a phase 2 study assessing the efficacy, safety, and tolerability of barasertib (AZD1152) versus low-dose cytosine arabinoside in elderly patients with acute myeloid leukemia

Kantarjian HM, Martinelli G, Jabbour EJ, Quintás-Cardama A, Ando K, Bay JO, Wei A, Gröpper S, Papayannidis C, Owen K, Pike L, Schmitt N, Stockman PK, Giagounidis A; SPARK-AML1 Investigators

(2013), Cancer, 19(14), 2611-9

Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma

Smeets MF, Chan AC, Dagger S, Bradley CK, Wei A, Izon DJ

(2013), PLoS One, 8(5), e62346

Modulating T regulatory cells in cancer: how close are we?

Banerjee A, Vasanthakumar A, Grigoriadis G

(2013), Immunol Cell Biol, 91(5), 340-9

Thymic regulatory T cell development: role of signalling pathways and transcription factors

Engel M, Sidwell T, Vasanthakumar A, Grigoriadis G, Banerjee A

(2013), Clin Dev Immunol, 2013, 617595

Tranexamic acid without prophylactic factor replacement for prevention of bleeding in hereditary bleeding disorder patients undergoing endoscopy: a pilot study

Davis A, Walsh M, McCarthy P, Brown G, Roberts S, Tran H, Street A, Fong CY, Kemp W

(2013), Haemophilia, 19(4), 583-9

Prevalence of transfusion-acquired hepatitis C in an Australian bleeding disorder population

Northcott MJ, Ong WL, Walsh M, McCarthy P, Belleli D, Tran H, Street A, Kemp W, Davis AK

(2013), Haemophilia, 19(6), 847-52

Central nervous system multiple myeloma--potential roles for intrathecal therapy and measurement of cerebrospinal fluid light chains

Lee D, Kalff A, Low M, Gangatharan S, Ho P, Bajel A, Ritchie D, Grigg A, Spencer A

(2013), Br J Haematol, 162(3), 371-5

Tissue-type plasminogen activator is an extracellular mediator of Purkinje cell damage and altered gait

Cops EJ, Sashindranath M, Daglas M, Short KM, da Fonseca Pereira C, Pang TY, Lijnen RH, Smyth IM, Hannan AJ, Samson AL, Medcalf RL

(2013), Exp Neurol, 249, 8-19

Limitations of targeted therapy with sorafenib in elderly high-risk myelodysplastic syndrome and acute myeloid leukemia

Wei A, Tan P

(2013), Leuk Lymphoma, 54(4), 675-6

GADD45A methylation predicts poor overall survival in acute myeloid leukemia and is associated with IDH1/2 and DNMT3A mutations

Perugini M, Iarossi DG, Kok CH, Cummings N, Diakiw SM, Brown AL, Danner S, Bardy P, Bik To L, Wei AH, Lewis ID, D'Andrea RJ

(2013), Leukemia, 27(7), 1588-92

High-dose cytarabine (24 g/m2) in combination with idarubicin (HiDAC-3) results in high first-cycle response with limited gastrointestinal toxicity in adult acute myeloid leukaemia

Low M, Lee D, Coutsouvelis J, Patil S, Opat S, Walker P, Schwarer A, Salem H, Avery S, Spencer A, Wei A

(2013), Intern Med J, 43(3), 294-7

Fludarabine, cytarabine, granulocyte-colony stimulating factor and amsacrine: an effective salvage therapy option for acute myeloid leukemia at first relapse

Fong CY, Grigoriadis G, Hocking J, Coutsouvelis J, Muirhead J, Campbell P, Paul E, Walker P, Avery S, Patil S, Spencer A, Schwarer A, Wei A

(2013), Leuk Lymphoma, 54(2), 336-41

Effectiveness of a single fixed dose of rasburicase 3 mg in the management of tumour lysis syndrome

Coutsouvelis J, Wiseman M, Hui L, Poole S, Dooley M, Patil S, Avery S, Wei A, Spencer A

(2013), Br J Clin Pharmacol, 75(2), 550-3

Two missense mutations identified in venous thrombosis patients impair the inhibitory function of the protein Z dependent protease inhibitor

Young LK, Birch NP, Browett PJ, Coughlin PB, Horvath AJ, Van de Water NS, Ockelford PA, Harper PL

(2012), Thromb Haemost, 107(5), 854-63

How to manage neutropenia in multiple myeloma

Palumbo A, Bladé J, Boccadoro M, Palladino C, Davies F, Dimopoulos M, Dmoszynska A, Einsele H, Moreau P, Sezer O, Spencer A, Sonneveld P, San Miguel J

(2012), Clin Lymphoma Myeloma Leuk, 12(1), 5-11

MyelomA Genetics International Consortium

Morgan G, Johnsen HE, Goldschmidt H, Palumbo A, Cavo M, Sonneveld P, Miguel JS, Chim CS, Browne P, Einsele H, Waage A, Turesson I, Spencer A, Hajek R, Ludwig H, Hemminki K, Houlston R

(2012), Leuk Lymphoma, 53(5), 796-800

Validation of whole blood impedance aggregometry as a new diagnostic tool for HIT: results of a large Australian study

Morel-Kopp MC, Tan CW, Brighton TA, McRae S, Baker R, Tran H, Mollee P, Kershaw G, Joseph J, Ward C; ASTH Clinical Trials Group

(2012), Thromb Haemost, 107(3), 575-83

Recommendations for the prevention of pregnancy-associated venous thromboembolism

McLintock C, Brighton T, Chunilal S, Dekker G, McDonnell N, McRae S, Muller P, Tran H, Walters BN, Young L; Councils of the Society of Obstetric Medicine of Australia and New Zealand; Australasian Society of Thrombosis and Haemostasis

(2012), Aust N Z J Obstet Gynaecol, 52(1), 3-13

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function

Mazharian A, Wang YJ, Mori J, Bem D, Finney B, Heising S, Gissen P, White JG, Berndt MC, Gardiner EE, Nieswandt B, Douglas MR, Campbell RD, Watson SP, Senis YA

(2012), Sci Signal, 5(248), ra78

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