Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Allelic imbalance of tissue-type plasminogen activator (t-PA) gene expression in human brain tissue

Tjarnlund-Wolf A, Hultman K, Curtis MA, Faull RL, Medcalf RL, Jern C

(2011), Thromb Haemost, 105(6), 945-53

Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF-ΚB pathway

Stankovic S, Gugasyan R, Kyparissoudis K, Grumont R, Banerjee A, Tsichlis P, Gerondakis S, Godfrey DI

(2011), Immunol Cell Biol, 89(2), 294-303

Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets

Schoenwaelder SM, Jarman KE, Gardiner EE, Hua M, Qiao J, White MJ, Josefsson EC, Alwis I, Ono A, Willcox A, Andrews RK, Mason KD, Salem HH, Huang DC, Kile BT, Roberts AW, Jackson SP

(2011), Blood, 118(6), 1663-74

Managing multiple myeloma in the elderly: are we making progress?

Quach H, Prince HM, Spencer A

(2011), Expert Rev Hematol, 4(3), 301-15

Asparaginase in the management of adult acute lymphoblastic leukaemia: is it used appropriately?

Patil S, Coutsouvelis J, Spencer A

(2011), Cancer Treat Rev, 37(3), 202-7

Rapid platelet accumulation leading to thrombotic occlusion

Para A, Bark D, Lin A, Ku D

(2011), Ann Biomed Eng, 39(7), 1961-71

Personalized therapy in multiple myeloma according to patient age and vulnerability: a report of the European Myeloma Network (EMN)

Palumbo A, Bringhen S, Ludwig H, Dimopoulos MA, Bladé J, Mateos MV, Rosiñol L, Boccadoro M, Cavo M, Lokhorst H, Zweegman S, Terpos E, Davies F, Driessen C, Gimsing P, Gramatzki M, Hàjek R, Johnsen HE, Leal Da Costa F, Sezer O, Spencer A, Beksac M, Morgan

(2011), Blood, 118(17), 4519-29

Thrombin-induced activation of astrocytes in mixed rat hippocampal cultures is inhibited by soluble thrombomodulin

Niego B, Samson AL, Petersen KU, Medcalf RL

(2011), Brain Res, 1381, 38-51

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation

Nguyen NY, Maxwell MJ, Ooms LM, Davies EM, Hilton AA, Collinge JE, Hilton DJ, Kile BT, Mitchell CA, Hibbs ML, Jane SM, Curtis DJ

(2011), Blood, 117(20), 5362-71

The role of the bone marrow microenvironment in multiple myeloma

Monaghan K, Spencer A

(2011), Eur J Clin Med Oncol, 3(2), 8

CYT997 causes apoptosis in human multiple myeloma

Monaghan K, Khong T, Smith G, Spencer A

(2011), Invest New Drugs, 29(2), 232-5

Antiplatelet drugs, anticoagulants and elective surgery

Merriman E, Tran H

(2011), Aust Prescr, 34(5), 139-43

Plasminogen activation-based thrombolysis for ischaemic stroke: the diversity of targets may demand new approaches

Medcalf RL

(2011), Curr Drug Targets, 12(12), 1772-81

The anti-leukemic effect and molecular mechanisms of novel hydroxamate and benzamide histone deacetylase inhibitors with 5-aza-cytidine

Liu HB, Mayes PA, Perlmutter P, McKendrick JJ, Dear AE

(2011), Int J Oncol, 38(5), 1421-5

Targeting HSP 90 induces apoptosis and inhibits critical survival and proliferation pathways in multiple myeloma

Khong T, Spencer A

(2011), Mol Cancer Ther, 10(10), 1909-17

The role of platelets in atherothrombosis

Kaplan ZS, Jackson SP

(2011), Hematology Am Soc Hematol Educ Program, 2011, 51-61

Arterial thrombosis - insidious, unpredictable and deadly

Jackson SP

(2011), Nat Med, 17(11), 1423-36

PPARγ-independent thiazolidinedione-mediated inhibition of NUR77 expression in vascular endothelial cells

Hu Y, Liu HB, Simpson RW, Dear AE

(2011), J Endocrinol, 208(1), R1-7

Collagen surfaces to measure thrombus formation under flow: possibilities for standardization

Heemskerk JW, Sakariassen KS, Zwaginga JJ, Brass LF, Jackson SP, Farndale RW; Biorheology Subcommittee of the SSC of the ISTH

(2011), J Thromb Haemost, 9(4), 856-8

A sensitized RNA interference screen identifies a novel role for the PI3K p110γ isoform in medulloblastoma cell proliferation and chemoresistance

Guerreiro AS, Fattet S, Kulesza DW, Atamer A, Elsing AN, Shalaby T, Jackson SP, Schoenwaelder SM, Grotzer MA, Delattre O, Arcaro A

(2011), Mol Cancer Res, 9(7), 925-35

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