Research publications

A microfluidics device to monitor platelet aggregation dynamics in response to strain rate micro-gradients in flowing blood

Tovar-Lopez FJ, Rosengarten G, Westein E, Khoshmanesh K, Jackson SP, Mitchell A, Nesbitt WS

(2010), Lab Chip, 10(3), 291-302

Transgenic, inducible RNAi in megakaryocytes and platelets in mice

Takiguchi M, James C, Josefsson EC, Carmichael CL, Premsrirut PK, Lowe SW, Hamilton JR, Huang DC, Kile BT, Dickins RA

(2010), J Thromb Haemost, 8(12), 2751-6

The plasminogen activator inhibitor 2 transcript is destabilized via a multi-component 3' UTR localized adenylate and uridylate-rich instability element in an analogous manner to cytokines and oncogenes

Stasinopoulos S, Mariasegaram M, Gafforini C, Nagamine Y, Medcalf RL

(2010), FEBS J, 277(5), 1331-44

No longer the poor relations

Spencer A

(2010), Blood, 116(19), 3685-6

Phosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces

Schoenwaelder SM, Ono A, Nesbitt WS, Lim J, Jarman K, Jackson SP

(2010), J Biol Chem, 285(4), 2886-96

Generation and characterization of mice with null mutation of the chloride intracellular channel 1 gene

Qiu MR, Jiang L, Matthaei KI, Schoenwaelder SM, Kuffner T, Mangin P, Joseph JE, Low J, Connor D, Valenzuela SM, Curmi PM, Brown LJ, Mahaut-Smith M, Jackson SP, Breit SN

(2010), Genesis, 48(2), 127-36

Proteolysis of platelet receptors in humans and other species

Qiao JL, Shen Y, Gardiner EE, Andrews RK

(2010), Biol Chem, 391(8), 893-900

Reduced-intensity conditioned allogeneic haematopoietic stem cell transplantation results in durable disease-free and overall survival in patients with poor prognosis myeloid and lymphoid malignancies: eighty-month follow-up

Patil S, Spencer A, Schwarer A, Lewis I, Hertzberg M, Avery S, Wei A, Noutsos T, Paul E, Taouk Y, Muirhead J

(2010), Bone Marrow Transplant, 45(7), 1154-60

Transmembrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibalpha

Mo X, Nguyen NX, Mu FT, Yang W, Luo SZ, Fan H, Andrews RK, Berndt MC, Li R

(2010), J Biol Chem, 285(42), 32096-104

Functional association of phosphoinositide-3-kinase with platelet glycoprotein Ibalpha, the major ligand-binding subunit of the glycoprotein Ib-IX-V complex

Mu FT, Cranmer SL, Andrews RK, Berndt MC

(2010), J Thromb Haemost, 8(2), 324-30

Deactylase inhibition in myeloproliferative neoplasms

Mithraprabhu S, Grigoriadis G, Khong T, Spencer A

(2010), Invest New Drugs, 28(Suppl 1), S50-7

Revisiting late relapses in acute myeloid leukemia

Minden M, Wei A

(2010), Leuk Lymphoma, 51(5), 735-6

Primary cardiac lymphoma

Mariani JA, Dawson MA, Avery S, Taylor AJ

(2010), J Am Coll Cardiol, 55(13), e23

Structural basis for apoptosis inhibition by Epstein-Barr virus BHRF1

Kvansakul M, Wei AH, Fletcher JI, Willis SN, Chen L, Roberts AW, Huang DC, Colman PM

(2010), PLoS Pathog, 6(12), e1001236

SR-BI and fatty platelets

Kaplan ZS, Jackson SP

(2010), Blood, 116(11), 1827-8

Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1

Jarman KE, Moretti PA, Zebol JR, Pitson SM

(2010), J Biol Chem, 285(1), 483-92

Procoagulant platelets: are they necrotic?

Jackson SP, Schoenwaelder SM

(2010), Blood, 116(12), 2011-8

Better quality of response to lenalidomide plus dexamethasone is associated with improved clinical outcomes in patients with relapsed or refractory multiple myeloma

Harousseau JL, Dimopoulos MA, Wang M, Corso A, Chen C, Attal M, Spencer A, Yu Z, Olesnyckyj M, Zeldis JB, Knight RD, Weber DM

(2010), Haematologica, 95(10), 1738-44

GPIbalpha-selective activation of platelets induces platelet signaling events comparable to GPVI activation events

Gardiner EE, Arthur JF, Shen Y, Karunakaran D, Moore LA, Am Esch JS 2nd, Andrews RK, Berndt MC

(2010), Platelets, 21(4), 244-52

Restored platelet function after romiplostim treatment in a patient with immune thrombocytopenic purpura

Gardiner EE, Thom JY, Al-Tamimi M, Hughes A, Berndt MC, Andrews RK, Baker RI

(2010), Br J Haematol, 149(4), 625-8

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