Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Arterial thrombosis: going, gone!

Gardiner EE, Berndt MC

(2010), Blood, 116(13), 2201-2

Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways

Garcia A, Kim S, Bhavaraju K, Schoenwaelder SM, Kunapuli SP

(2010), Biochem J, 429(2), 369-77

Genetic and epigenetic mechanisms and their possible role in abdominal aortic aneurysm

Krishna SM, Dear AE, Norman PE, Golledge J

(2010), Atherosclerosis, 212(1), 16-29

Association of statin prescription with small abdominal aortic aneurysm progression

Ferguson CD, Clancy P, Bourke B, Walker PJ, Dear A, Buckenham T, Norman P, Golledge J

(2010), Am Heart J, 159(2), 307-13

European Myeloma Network: the 3rd Trialist Forum Consensus Statement from the European experts meeting on multiple myeloma

Engelhardt M, Udi J, Kleber M, Spencer A, Rocci A, Knop S, Bruno B, Bringhen S, Pérez-Simón JA, Zweegman S, Driessen C, Patriarca F, Gramatzki M, Terpos E, Sezer O, Kropff M, Straka C…….

(2010), Leuk Lymphoma, 51(11), 2006-11

Consensus statement from European experts on the diagnosis, management, and treatment of multiple myeloma: from standard therapy to novel approaches

Engelhardt M, Kleber M, Udi J, Wäsch R, Spencer A, Patriarca F, Knop S, Bruno B, Gramatzki M, Morabito F, Kropff M, Neri A, Sezer O, Hajek R, Bunjes D, Boccadoro M, Straka C, Cavo M, Polliack A, Einsele H, Palumbo A

(2010), Leuk Lymphoma, 51(8), 1424-43

The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity

Dharmarajah J, Arthur JF, Sobey CG, Drummond GR

(2010), Naunyn Schmiedebergs Arch Pharmacol, 382(4), 377-84

Cord blood transplants: one, two or more units?

Avery S, Barker JN

(2010), Curr Opin Hematol, 17(6), 531-7

Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway

Devi S, Kuligowski MP, Kwan RY, Westein E, Jackson SP, Kitching AR, Hickey MJ

(2010), Am J Pathol, 177(3), 1131-42

PI 3-kinase p110beta regulation of platelet integrin alphaIIbbeta3

Jackson SP, Schoenwaelder SM

(2010), In: Rommel C, Vanhaesebroeck B, Vogt PK (eds), Current Topics in Microbiology and Immunology, Vol 346, Phosphoinositide 3-kinase in Health and Disease, Springer-Verlag, Berlin, Germany, 203-24

New insights into the haemostatic function of platelets

Wei AH, Schoenwaelder SM, Andrews RK, Jackson SP

(2009), Br J Haematol, 147(4), 415-30

An open-label, phase 2 trial of denosumab in the treatment of relapsed or plateau-phase multiple myeloma

Vij R, Horvath N, Spencer A, Taylor K, Vadhan-Raj S, Vescio R, Smith J, Qian Y, Yeh H, Jun S

(2009), Am J Hematol, 84(10), 650-6

Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure

Spencer A, Prince HM, Roberts AW, Prosser IW, Bradstock KF, Coyle L, Gill DS, Horvath N, Reynolds J, Kennedy N

(2009), J Clin Oncol, 27(11), 1788-93

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function

Schoenwaelder SM, Yuan Y, Josefsson EC, White MJ, Yao Y, Mason KD, O'Reilly LA, Henley KJ, Ono A, Hsiao S, Willcox A, Roberts AW, Huang DC, Salem HH, Kile BT, Jackson SP

(2009), Blood, 114(3), 663-6

A nonfibrin macromolecular cofactor for tPA-mediated plasmin generation following cellular injury

Samson AL, Borg RJ, Niego B, Wong CH, Crack PJ, Yongqing T, Medcalf RL

(2009), Blood, 114(9), 1937-46

A novel histone deacetylase inhibitor augments tamoxifen-mediated attenuation of breast carcinoma growth

Restall C, Doherty J, Liu HB, Genovese R, Paiman L, Byron KA, Anderson RL, Dear AE

(2009), Int J Cancer, 125(2), 483-7

Vascular endothelial growth factor inhibition is not an effective therapeutic strategy for relapsed or refractory multiple myeloma: a phase 2 study of pazopanib (GW786034)

Prince HM, Hönemann D, Spencer A, Rizzieri DA, Stadtmauer EA, Roberts AW, Bahlis N, Tricot G, Bell B, Demarini DJ, Benjamin Suttle A, Baker KL, Pandite LN

(2009), Blood, 113(19), 4819-20

International Myeloma Working Group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation

Palumbo A, Sezer O, Kyle R, Miguel JS, Orlowski RZ, et al; IMWG

(2009), Leukemia, 23(10), 1716-30

A shear gradient-dependent platelet aggregation mechanism drives thrombus formation

Nesbitt WS, Westein E, Tovar-Lopez FJ, Tolouei E, Mitchell A, Fu J, Carberry J, Fouras A, Jackson SP

(2009), Nat Med, 15(6), 665-73

Long-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma

Dimopoulos MA, Chen C, Spencer A, Niesvizky R, Attal M, Stadtmauer EA, Petrucci MT, Yu Z, Olesnyckyj M, Zeldis JB, Knight RD, Weber DM

(2009), Leukemia, 23(11), 2147-52