Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Prosthetic pulmonary valve thrombosis in pregnancy successfully treated with thrombolysis

Wei A, Alison J, Goldstein J, Tippett C, Coughlan PB

(2008), Intern Med J, 38(2), 142-3

Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure

Wang M, Dimopoulos MA, Chen C, Cibeira MT, Attal M, Spencer A, Rajkumar SV, Yu Z, Olesnyckyj M, Zeldis JB, Knight RD, Weber DM

(2008), Blood, 112(12), 4445-51

A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice

Vinh A, Gaspari TA, Liu HB, Dousha LF, Widdop RE, Dear AE

(2008), J Vasc Res, 45(2), 143-52

Dual P2Y 12 receptor signaling in thrombin-stimulated platelets--involvement of phosphoinositide 3-kinase beta but not gamma isoform in Ca2+ mobilization and procoagulant activity

van der Meijden PE, Schoenwaelder SM, Feijge MA, Cosemans JM, Munnix IC, Wetzker R, Heller R, Jackson SP, Heemskerk JW

(2008), FEBS J, 275(2), 371-85

Enhanced immune system regeneration in humans following allogeneic or autologous hemopoietic stem cell transplantation by temporary sex steroid blockade

Sutherland JS, Spyroglou L, Muirhead JL, Heng TS, Prieto-Hinojosa A, Prince HM, Chidgey AP, Schwarer AP, Boyd RL

(2008), Clin Cancer Res, 14(4), 1138-49

Renal safety of zoledronic acid with thalidomide in patients with myeloma: a pharmacokinetic and safety sub-study

Spencer A, Roberts A, Kennedy N, Ravera C, Cremers S, Bilic S, Neeman T, Copeman M, Schran H, Lynch K

(2008), BMC Clin Pharmacol, 8, 2

Guidelines for the prevention of sepsis in asplenic and hyposplenic patients

Spelman D, Buttery J, Daley A, Isaacs D, Jennens I, Kakakios A, Lawrence R, Roberts S, Torda A, Watson DA, Woolley I, Anderson T, Street A; Australasian Society for Infectious Diseases

(2008), Intern Med J, 38(5), 349-56

Combined pegylated liposomal doxorubicin and bortezomib is highly effective in patients with recurrent or refractory multiple myeloma who received prior thalidomide/lenalidomide therapy

Sonneveld P, Hajek R, Nagler A, Spencer A, Blade J, Robak T, Zhuang SH, Harousseau JL, Orlowski RZ; DOXIL-MMY-3001 Study Investigators

(2008), Cancer, 112(7), 1529-37

Low molecular weight contaminants in commercial preparations of plasmin and t-PA activate neurons

Samson AL, Nevin ST, Medcalf RL

(2008), J Thromb Haemost, 6(12), 2218-20

Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function

Samson AL, Nevin ST, Croucher D, Niego B, Daniel PB, Weiss TW, Moreno E, Monard D, Lawrence DA, Medcalf RL

(2008), J Neurochem, 107(4), 1091-101

A drop of vitriol: microspherocytosis following sulphuric acid exposure

Polizzotto MN, Shortt J, Opat SS, Cole-Sinclair MF

(2008), Br J Haematol, 140(6), 596

Expression of the serpin centerin defines a germinal center phenotype in B-cell lymphomas

Paterson MA, Hosking PS, Coughlin PB

(2008), Am J Clin Pathol, 130(1), 117-26

A multicenter phase 2 study of risk-adjusted salvage chemotherapy incorporating vinorelbine and gemcitabine for relapsed and refractory lymphoma

Pasricha SR, Grigg A, Catalano J, Leahy M, Underhill C, Arthur C, D'Rozario J, Lowenthal R, Reed K, Spencer A

(2008), Cancer, 113(11), 3192-8

Thalidomide for treatment of multiple myeloma: 10 years later

Palumbo A, Facon T, Sonneveld P, Blade J, Offidani M, Gay F, Moreau P, Waage A, Spencer A, Ludwig H, Boccadoro M, Harousseau JL

(2008), Blood, 111(8), 3968-77

Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth

Ono A, Westein E, Hsiao S, Nesbitt WS, Hamilton JR, Schoenwaelder SM, Jackson SP

(2008), Blood, 112(1), 90-9

Desmoteplase-mediated plasminogen activation and clot lysis are inhibited by the lysine analogue tranexamic acid

Niego B, Horvath A, Coughlin PB, Pugsley MK, Medcalf RL

(2008), Blood Coagul Fibrinolysis, 19(4), 322-4

Refinement in the production and purification of recombinant HCMV IE1-pp65 protein for the generation of epitope-specific T cell immunity

Nguyen TH, Mifsud NA, Stewart LA, Rose MJ, Etto TL, Williamson NA, Purcell AW, Kotsimbos T, Schwarer AP

(2008), Protein Expr Purif, 61(1), 22-30

Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin

Newbold A, Lindemann RK, Cluse LA, Whitecross KF, Dear AE, Johnstone RW

(2008), Mol Cancer Ther, 7(5), 1066-79

Mannose-binding lectin status is associated with risk of major infection following myeloablative sibling allogeneic hematopoietic stem cell transplantation

Mullighan CG, Heatley SL, Danner S, Dean MM, Doherty K, Hahn U, Bradstock KF, Minchinton R, Schwarer AP, Szer J, Bardy PG

(2008), Blood, 112(5), 2120-8

A functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex

Mu FT, Andrews RK, Arthur JF, Munday AD, Cranmer SL, Jackson SP, Stomski FC, Lopez AF, Berndt MC

(2008), Blood, 111(9), 4580-7

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