Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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Prognostically significant cytotoxic T cell clones are stimulated after thalidomide therapy in patients with multiple myeloma

Brown RD, Spencer A, Ho PJ, Kennedy N, Kabani K, Yang S, Sze DM, Aklilu E, Gibson J, Joshua DE

(2009), Leuk Lymphoma, 50(11), 1860-4

Is thrombin the problem or (dis)solution?

Arthur JF, Jackson SP

(2009), Blood, 113(24), 6046-7

Measuring soluble platelet glycoprotein VI in human plasma by ELISA

Al-Tamimi M, Mu FT, Moroi M, Gardiner EE, Berndt MC, Andrews RK

(2009), Platelets, 20(3), 143-9

Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding

Al-Tamimi M, Mu FT, Arthur JF, Shen Y, Moroi M, Berndt MC, Andrews RK, Gardiner EE

(2009), Platelets, 20(2), 75-82

Disease status at autologous stem cell transplantation and the cell of origin phenotype are important predictors of outcome in patients with neurologic (central nervous system) relapse of diffuse large B-cell lymphoma undergoing autologous stem cell......

Patil S, Spencer A, Schwarer A, Avery S, Ritchie D, Opat S, Wei A, McLean C

(2009), Leuk Lymphoma, 50(12), 1964-8

The novel histone deacetylase inhibitors metacept-1 and metacept-3 potently increase HIV-1 transcription in latently infected cells

Shehu-Xhilaga M, Rhodes D, Wightman F, Liu HB, Solomon A, Saleh S, Dear AE, Cameron PU, Lewin SR

(2009), AIDS, 23(15), 2047-50

Bortezomib: putting mantle cell lymphoma on death row

Wei AH, Roberts AW

(2008), Leuk Lymphoma, 49(4), 657-8

Boosting platelet production

Wei A, Jackson SP

(2008), Nat Med, 14(9), 917-8

Prosthetic pulmonary valve thrombosis in pregnancy successfully treated with thrombolysis

Wei A, Alison J, Goldstein J, Tippett C, Coughlan PB

(2008), Intern Med J, 38(2), 142-3

Lenalidomide plus dexamethasone is more effective than dexamethasone alone in patients with relapsed or refractory multiple myeloma regardless of prior thalidomide exposure

Wang M, Dimopoulos MA, Chen C, Cibeira MT, Attal M, Spencer A, Rajkumar SV, Yu Z, Olesnyckyj M, Zeldis JB, Knight RD, Weber DM

(2008), Blood, 112(12), 4445-51

A novel histone deacetylase inhibitor reduces abdominal aortic aneurysm formation in angiotensin II-infused apolipoprotein E-deficient mice

Vinh A, Gaspari TA, Liu HB, Dousha LF, Widdop RE, Dear AE

(2008), J Vasc Res, 45(2), 143-52

Dual P2Y 12 receptor signaling in thrombin-stimulated platelets--involvement of phosphoinositide 3-kinase beta but not gamma isoform in Ca2+ mobilization and procoagulant activity

van der Meijden PE, Schoenwaelder SM, Feijge MA, Cosemans JM, Munnix IC, Wetzker R, Heller R, Jackson SP, Heemskerk JW

(2008), FEBS J, 275(2), 371-85

Enhanced immune system regeneration in humans following allogeneic or autologous hemopoietic stem cell transplantation by temporary sex steroid blockade

Sutherland JS, Spyroglou L, Muirhead JL, Heng TS, Prieto-Hinojosa A, Prince HM, Chidgey AP, Schwarer AP, Boyd RL

(2008), Clin Cancer Res, 14(4), 1138-49

Renal safety of zoledronic acid with thalidomide in patients with myeloma: a pharmacokinetic and safety sub-study

Spencer A, Roberts A, Kennedy N, Ravera C, Cremers S, Bilic S, Neeman T, Copeman M, Schran H, Lynch K

(2008), BMC Clin Pharmacol, 8, 2

Guidelines for the prevention of sepsis in asplenic and hyposplenic patients

Spelman D, Buttery J, Daley A, Isaacs D, Jennens I, Kakakios A, Lawrence R, Roberts S, Torda A, Watson DA, Woolley I, Anderson T, Street A; Australasian Society for Infectious Diseases

(2008), Intern Med J, 38(5), 349-56

Combined pegylated liposomal doxorubicin and bortezomib is highly effective in patients with recurrent or refractory multiple myeloma who received prior thalidomide/lenalidomide therapy

Sonneveld P, Hajek R, Nagler A, Spencer A, Blade J, Robak T, Zhuang SH, Harousseau JL, Orlowski RZ; DOXIL-MMY-3001 Study Investigators

(2008), Cancer, 112(7), 1529-37

Low molecular weight contaminants in commercial preparations of plasmin and t-PA activate neurons

Samson AL, Nevin ST, Medcalf RL

(2008), J Thromb Haemost, 6(12), 2218-20

Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function

Samson AL, Nevin ST, Croucher D, Niego B, Daniel PB, Weiss TW, Moreno E, Monard D, Lawrence DA, Medcalf RL

(2008), J Neurochem, 107(4), 1091-101

A drop of vitriol: microspherocytosis following sulphuric acid exposure

Polizzotto MN, Shortt J, Opat SS, Cole-Sinclair MF

(2008), Br J Haematol, 140(6), 596

Expression of the serpin centerin defines a germinal center phenotype in B-cell lymphomas

Paterson MA, Hosking PS, Coughlin PB

(2008), Am J Clin Pathol, 130(1), 117-26