Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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The anti-platelet effects of apocynin in mice are not mediated by inhibition of NADPH oxidase activity

Dharmarajah J, Arthur JF, Sobey CG, Drummond GR

(2010), Naunyn Schmiedebergs Arch Pharmacol, 382(4), 377-84

Cord blood transplants: one, two or more units?

Avery S, Barker JN

(2010), Curr Opin Hematol, 17(6), 531-7

Platelet recruitment to the inflamed glomerulus occurs via an alphaIIbbeta3/GPVI-dependent pathway

Devi S, Kuligowski MP, Kwan RY, Westein E, Jackson SP, Kitching AR, Hickey MJ

(2010), Am J Pathol, 177(3), 1131-42

PI 3-kinase p110beta regulation of platelet integrin alphaIIbbeta3

Jackson SP, Schoenwaelder SM

(2010), In: Rommel C, Vanhaesebroeck B, Vogt PK (eds), Current Topics in Microbiology and Immunology, Vol 346, Phosphoinositide 3-kinase in Health and Disease, Springer-Verlag, Berlin, Germany, 203-24

New insights into the haemostatic function of platelets

Wei AH, Schoenwaelder SM, Andrews RK, Jackson SP

(2009), Br J Haematol, 147(4), 415-30

An open-label, phase 2 trial of denosumab in the treatment of relapsed or plateau-phase multiple myeloma

Vij R, Horvath N, Spencer A, Taylor K, Vadhan-Raj S, Vescio R, Smith J, Qian Y, Yeh H, Jun S

(2009), Am J Hematol, 84(10), 650-6

Consolidation therapy with low-dose thalidomide and prednisolone prolongs the survival of multiple myeloma patients undergoing a single autologous stem-cell transplantation procedure

Spencer A, Prince HM, Roberts AW, Prosser IW, Bradstock KF, Coyle L, Gill DS, Horvath N, Reynolds J, Kennedy N

(2009), J Clin Oncol, 27(11), 1788-93

Two distinct pathways regulate platelet phosphatidylserine exposure and procoagulant function

Schoenwaelder SM, Yuan Y, Josefsson EC, White MJ, Yao Y, Mason KD, O'Reilly LA, Henley KJ, Ono A, Hsiao S, Willcox A, Roberts AW, Huang DC, Salem HH, Kile BT, Jackson SP

(2009), Blood, 114(3), 663-6

A nonfibrin macromolecular cofactor for tPA-mediated plasmin generation following cellular injury

Samson AL, Borg RJ, Niego B, Wong CH, Crack PJ, Yongqing T, Medcalf RL

(2009), Blood, 114(9), 1937-46

A novel histone deacetylase inhibitor augments tamoxifen-mediated attenuation of breast carcinoma growth

Restall C, Doherty J, Liu HB, Genovese R, Paiman L, Byron KA, Anderson RL, Dear AE

(2009), Int J Cancer, 125(2), 483-7

Vascular endothelial growth factor inhibition is not an effective therapeutic strategy for relapsed or refractory multiple myeloma: a phase 2 study of pazopanib (GW786034)

Prince HM, Hönemann D, Spencer A, Rizzieri DA, Stadtmauer EA, Roberts AW, Bahlis N, Tricot G, Bell B, Demarini DJ, Benjamin Suttle A, Baker KL, Pandite LN

(2009), Blood, 113(19), 4819-20

International Myeloma Working Group guidelines for the management of multiple myeloma patients ineligible for standard high-dose chemotherapy with autologous stem cell transplantation

Palumbo A, Sezer O, Kyle R, Miguel JS, Orlowski RZ, et al; IMWG

(2009), Leukemia, 23(10), 1716-30

A shear gradient-dependent platelet aggregation mechanism drives thrombus formation

Nesbitt WS, Westein E, Tovar-Lopez FJ, Tolouei E, Mitchell A, Fu J, Carberry J, Fouras A, Jackson SP

(2009), Nat Med, 15(6), 665-73

Long-term follow-up on overall survival from the MM-009 and MM-010 phase III trials of lenalidomide plus dexamethasone in patients with relapsed or refractory multiple myeloma

Dimopoulos MA, Chen C, Spencer A, Niesvizky R, Attal M, Stadtmauer EA, Petrucci MT, Yu Z, Olesnyckyj M, Zeldis JB, Knight RD, Weber DM

(2009), Leukemia, 23(11), 2147-52

Glycoprotein Ibalpha inhibitor complex structure reveals a combined steric and allosteric mechanism of von Willebrand factor antagonism

McEwan PA, Andrews RK, Emsley J

(2009), Blood, 114(23), 4883-5

Specific function of phosphoinositide 3-kinase beta in the control of DNA replication

Marqués M, Kumar A, Poveda AM, Zuluaga S, Hernández C, Jackson S, Pasero P, Carrera AC

(2009), Proc Natl Acad Sci USA, 106(18), 7525-30

The anti-leukemic effect of a novel histone deacetylase inhibitor MCT-1 and 5-aza-cytidine involves augmentation of Nur77 and inhibition of MMP-9 expression

Liu HB, Voso MT, Gumiero D, Duong J, McKendrick JJ, Dear AE

(2009), Int J Oncol, 34(2), 573-9

A long-acting glucagon-like peptide-1 analogue attenuates induction of plasminogen activator inhibitor type-1 and vascular adhesion molecules

Liu H, Dear AE, Knudsen LB, Simpson RW

(2009), J Endocrinol, 201(1), 59-66

The identification of a calmodulin-binding domain within the cytoplasmic tail of angiotensin-converting enzyme-2

Lai ZW, Lew RA, Yarski MA, Mu FT, Andrews RK, Smith AI

(2009), Endocrinology, 150(5), 2376-81

Role of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets

Kim S, Mangin P, Dangelmaier C, Lillian R, Jackson SP, Daniel JL, Kunapuli SP

(2009), J Biol Chem, 284(49), 33763-72

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