Research publications

Alfred Health research outcomes are published in a wide range of peer reviewed journals. 

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The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes

Gray LR, Tachedjian G, Ellett AM, Roche MJ, Cheng WJ, Guillemin GJ, Brew BJ, Turville SG, Wesselingh SL, Gorry PR, Churchill MJ

(2013), PLoS One, 8(4), e62196

The magnitude of HIV-1 resistance to the CCR5 antagonist maraviroc may impart a differential alteration in HIV-1 tropism for macrophages and T-cell subsets

Flynn JK, Paukovics G, Moore MS, Ellett A, Gray LR, Duncan R, Salimi H, Jubb B, Westby M, Purcell DF, Lewin SR, Lee B, Churchill MJ, Gorry PR, Roche M

(2013), Virology, 442(1), 51-8

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations

Roche M, Salimi H, Duncan R, Wilkinson BL, Chikere K, Moore MS, Webb NE, Zappi H, Sterjovski J, Flynn JK, Ellett A, Gray LR, Lee B, Jubb B, Westby M, Ramsland PA, Lewin SR, Payne RJ, Churchill MJ, Gorry PR

(2013), Retrovirology, 10, 43

Galactomannan and PCR versus culture and histology for directing use of antifungal treatment for invasive aspergillosis in high-risk haematology patients: a randomised controlled trial

Morrissey CO, Chen SC, Sorrell TC, Milliken S, Bardy PG, Bradstock KF, Szer J, Halliday CL, Gilroy NM, Moore J, Schwarer AP, Guy S, Bajel A, Tramontana AR, Spelman T, Slavin MA; Australasian Leukaemia Lymphoma Group and the Australia and New Zealand Mycol

(2013), Lancet Infect Dis, 13(6), 519-28

Maintenance of Th1 hepatitis C virus (HCV)-specific responses in individuals with acute HCV who achieve sustained virological clearance after treatment

Flynn JK, Dore GJ, Hellard M, Yeung B, Rawlinson WD, White PA, Kaldor JM, Lloyd AR, Ffrench RA; ATAHC Study Group

(2013), J Gastroenterol Hepatol, 28(11), 1770-81

An unusual case of HIV virologic failure during treatment with boosted atazanavir

Duncan A, Mills J

(2013), AIDS, 27(8), 1361-2

HIV epidemic in men who have sex with men in Philippines

Ross AG, Ditangco RA, Belimac JG, Olveda RM, Mercado ES, Rogers GD, Cripps AW, Lam A, Crowe SM

(2013), Lancet Infect Dis, 13(6), 472-3

Characteristics of a sexual network of behaviorally bisexual men in Vientiane, Lao PDR, 2010

van Gemert C, Vongsaiya K, Hughes C, Jenkinson R, Bowring AL, Sihavong A, Phimphachanh C, Chanlivong N, Toole M, Hellard M

(2013), AIDS Educ Prev, 25(3), 232-43

Longitudinal analysis of CCR5 and CXCR4 usage in a cohort of antiretroviral therapy-naive subjects with progressive HIV-1 subtype C infection

Jakobsen MR, Cashin K, Roche M, Sterjovski J, Ellett A, Borm K, Flynn J, Erikstrup C, Gouillou M, Gray LR, Saksena NK, Wang B, Purcell DF, Kallestrup P, Zinyama-Gutsire R, Gomo E, Ullum H, Ostergaard L, Lee B, Ramsland PA, Churchill MJ, Gorry PR

(2013), PLoS One, 8(6), e65950

Cryptococcosis-IRIS is associated with lower cryptococcus-specific IFN-γ responses before antiretroviral therapy but not higher T-cell responses during therapy

Chang CC, Lim A, Omarjee S, Levitz SM, Gosnell BI, Spelman T, Elliott JH, Carr WH, Moosa MY, Ndung'u T, Lewin SR, French MA

(2013), J Infect Dis, 208(6), 898-906

A cure for HIV: where we've been, and where we're headed

Lewin SR

(2013), Lancet, 381(9883), 2057-8

HIV and co-infections

Chang CC, Crane M, Zhou J, Mina M, Post JJ, Cameron BA, Lloyd AR, Jaworowski A, French MA, Lewin SR

(2013), Immunol Rev, 254(1), 114-42

Introduction of a sexual health practice nurse is associated with increased STI testing of men who have sex with men in primary care

Snow AF, Vodstrcil LA, Fairley CK, El-Hayek C, Cummings R, Owen L, Roth N, Hellard ME, Chen MY

(2013), BMC Infect Dis, 13, 298

Altering cell death pathways as an approach to cure HIV infection

Badley AD, Sainski A, Wightman F, Lewin SR

(2013), Cell Death Dis, 4, e718

Impact of HIV-associated conditions on mortality in people commencing anti-retroviral therapy in resource limited settings

Marshall CS, Curtis AJ, Spelman T, O'Brien DP, Greig J, Shanks L, du Cros P, Casas EC, da Fonseca MS, Athan E, Elliott JH

(2013), PLoS One, 8(7), e68445

Treatment of hepatitis C virus infection among people who are actively injecting drugs: a systematic review and meta-analysis

Aspinall EJ, Corson S, Doyle JS, Grebely J, Hutchinson SJ, Dore GJ, Goldberg DJ, Hellard ME

(2013), Clin Infect Dis, 57 Suppl 2, S80-9

Chemokine levels and chemokine receptor expression in the blood and the cerebrospinal fluid of HIV-infected patients with cryptococcal meningitis and cryptococcosis-associated immune reconstitution inflammatory syndrome

Chang CC, Omarjee S, Lim A, Spelman T, Gosnell BI, Carr WH, Elliott JH, Moosa MY, Ndung'u T, French MA, Lewin SR

(2013), J Infect Dis, 208(10), 1604-12

Improved neurocognitive test performance in both arms of the SMART study: impact of practice effect

Grund B, Wright EJ, Brew BJ, Price RW, Roediger MP, Bain MP, Hoy JF, Shlay JC, Vjecha MJ, Robertson KR; INSIGHT SMART Study Group

(2013), J Neurovirol, 19(4), 383-92

Are Australian sexual health clinics attracting priority populations?

Ali H, Donovan B, Fairley CK, Ryder N, McNulty A, Chen MY, Marshall L, O'Connor CC, Dickson B, Grulich AE, Hellard ME, Kaldor JM, Guy RJ; ACCESS Collaboration

(2013), Sex Health, 10(5), 456-9

Opt-out and opt-in testing increases syphilis screening of HIV-positive men who have sex with men in Australia

Guy R, El-Hayek C, Fairley CK, Wand H, Carr A, McNulty A, Hoy J, Bourne C, McAllister J, Tee BK, Baker D, Roth N, Stoove M, Chen M

(2013), PLoS One, 8(8), e71436